Predictive modelling of topology and loop variations in dimeric DNA quadruplex structures

por Hazel, Pascale, Parkinson, Gary N, Neidle, Stephen
Publicado 2006

G-Quadruplexes (GQU)

por Haider, Shozeb, Parkinson, Gary N., Marsh, Thomas C.
Publicado 2018

Crystal structures of PI3K-C2α PX domain indicate conformational change associated with ligand binding

por Parkinson, Gary N, Vines, David, Driscoll, Paul C, Djordjevic, Snezana
Publicado 2008

Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation

por Wei, Dengguo, Parkinson, Gary N., Reszka, Anthony P., Neidle, Stephen
Publicado 2012

Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter

por Todd, Alan K., Haider, Shozeb M., Parkinson, Gary N., Neidle, Stephen
Publicado 2007

A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex

por Collie, Gavin W., Haider, Shozeb M., Neidle, Stephen, Parkinson, Gary N.
Publicado 2010

Quadruplex DNA: sequence, topology and structure

por Burge, Sarah, Parkinson, Gary N., Hazel, Pascale, Todd, Alan K., Neidle, Stephen
Publicado 2006

A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3)

por Shih, Po-Chang, Yang, Yiwen, Parkinson, Gary N., Wilderspin, Andrew, Wells, Geoffrey
Publicado 2018

C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes

por Fratta, Pietro, Mizielinska, Sarah, Nicoll, Andrew J., Zloh, Mire, Fisher, Elizabeth M. C., Parkinson, Gary, Isaacs, Adrian M.
Publicado 2012

Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths

por Zhang, Yashu, El Omari, Kamel, Duman, Ramona, Liu, Sisi, Haider, Shozeb, Wagner, Armin, Parkinson, Gary N, Wei, Dengguo
Publicado 2020

Towards the Inhibition of Protein–Protein Interactions (PPIs) in STAT3: Insights into a New Class of Benzothiadiazole Derivatives

por Mori, Matteo, Gilardoni, Ettore, Regazzoni, Luca, Pedretti, Alessandro, Colombo, Diego, Parkinson, Gary, Asai, Akira, Meneghetti, Fiorella, Villa, Stefania, Gelain, Arianna
Publicado 2020

Mechanistic In Situ and Ex Situ Studies of Phase Transformations in Molecular Co‐Crystals

por Clout, Alexander E., Buanz, Asma B. M., Pang, Yuying, Tsui, Wing‐Mei, Yan, Dongpeng, Parkinson, Gary, Prior, Timothy J., Bučar, Dejan‐Krešimir, Gaisford, Simon, Williams, Gareth R.
Publicado 2020

BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers

por Gao, Chao, Liu, Zhu, Hou, Haitao, Ding, Jieqin, Chen, Xin, Xie, Congbao, Song, Zibing, Hu, Zhe, Feng, Mingqian, Mohamed, Hany I, Xu, Shengzhen, Parkinson, Gary N, Haider, Shozeb, Wei, Dengguo
Publicado 2020

Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin

por Stowe, Cassandra L, Burley, Thomas A, Allan, Helen, Vinci, Maria, Kramer-Marek, Gabriela, Ciobota, Daniela M, Parkinson, Gary N, Southworth, Tara L, Agliardi, Giulia, Hotblack, Alastair, Lythgoe, Mark F, Branchini, Bruce R, Kalber, Tammy L, Anderson, James C, Pule, Martin A
Publicado 2019

G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

por Simone, Roberto, Balendra, Rubika, Moens, Thomas G, Preza, Elisavet, Wilson, Katherine M, Heslegrave, Amanda, Woodling, Nathan S, Niccoli, Teresa, Gilbert‐Jaramillo, Javier, Abdelkarim, Samir, Clayton, Emma L, Clarke, Mica, Konrad, Marie‐Therese, Nicoll, Andrew J, Mitchell, Jamie S, Calvo, Andrea, Chio, Adriano, Houlden, Henry, Polke, James M, Ismail, Mohamed A, Stephens, Chad E, Vo, Tam, Farahat, Abdelbasset A, Wilson, W David, Boykin, David W, Zetterberg, Henrik, Partridge, Linda, Wray, Selina, Parkinson, Gary, Neidle, Stephen, Patani, Rickie, Fratta, Pietro, Isaacs, Adrian M
Publicado 2017