Augmenting the logrank test in the design of clinical trials in which non-proportional hazards of the treatment effect may be anticipated

por Royston, Patrick, Parmar, Mahesh K.B.
Publicado 2016

A simulation study comparing the power of nine tests of the treatment effect in randomized controlled trials with a time-to-event outcome

por Royston, Patrick, B. Parmar, Mahesh K.
Publicado 2020

Take-Home Emergency Naloxone to Prevent Heroin Overdose Deaths after Prison Release: Rationale and Practicalities for the N-ALIVE Randomized Trial

por Strang, John, Bird, Sheila M., Parmar, Mahesh K. B.
Publicado 2013

Take-home naloxone to prevent fatalities from opiate-overdose: Protocol for Scotland's public health policy evaluation, and a new measure to assess impact

por Bird, Sheila M., Parmar, Mahesh K. B., Strang, John
Publicado 2015

The extension of total gain (TG) statistic in survival models: properties and applications

por Choodari-Oskooei, Babak, Royston, Patrick, Parmar, Mahesh K.B.
Publicado 2015

How do you design randomised trials for smaller populations? A framework

por Parmar, Mahesh K. B., Sydes, Matthew R., Morris, Tim P.
Publicado 2016

Effectiveness and acceptability of methods of communicating the results of clinical research to lay and professional audiences: protocol for a systematic review

por South, Annabelle, Bailey, Julia, Parmar, Mahesh K. B., Vale, Claire L.
Publicado 2019

A Quantitative Process for Enhancing End of Phase 2 Decisions

por Sabin, Tony, Matcham, James, Bray, Sarah, Copas, Andrew, Parmar, Mahesh K. B.
Publicado 2014

Combined test versus logrank/Cox test in 50 randomised trials

por Royston, Patrick, Choodari-Oskooei, Babak, Parmar, Mahesh K. B., Rogers, Jennifer K.
Publicado 2019

Is It Possible to Conduct a Multi-Arm Multi-Stage Platform Trial in Parkinson’s Disease: Lessons Learned from Other Neurodegenerative Disorders and Cancer

por Zeissler, Marie-Louise, Li, Vivien, Parmar, Mahesh K.B., Carroll, Camille Buchholz
Publicado 2020

Type I error rates of multi-arm multi-stage clinical trials: strong control and impact of intermediate outcomes

por Bratton, Daniel J., Parmar, Mahesh K. B., Phillips, Patrick P. J., Choodari-Oskooei, Babak
Publicado 2016

Randomized controlled pilot trial of naloxone‐on‐release to prevent post‐prison opioid overdose deaths

por Parmar, Mahesh K. B., Strang, John, Choo, Louise, Meade, Angela M., Bird, Sheila M.
Publicado 2016

Comparison of aggregate and individual participant data approaches to meta-analysis of randomised trials: An observational study

por Tierney, Jayne F., Fisher, David J., Burdett, Sarah, Stewart, Lesley A., Parmar, Mahesh K. B.
Publicado 2020

Uptake of the multi-arm multi-stage (MAMS) adaptive platform approach: a trial-registry review of late-phase randomised clinical trials

por Noor, Nurulamin M, Love, Sharon B, Isaacs, Talia, Kaplan, Richard, Parmar, Mahesh K B, Sydes, Matthew R
Publicado 2022

artbin: Extended sample size for randomized trials with binary outcomes

por Marley-Zagar, Ella, White, Ian R., Royston, Patrick, Barthel, Friederike M.-S., Parmar, Mahesh K. B., Babiker, Abdel G.
Publicado 2023

Should Tyrosine Kinase Inhibitors Be Considered for Advanced Non–Small-Cell Lung Cancer Patients With Wild Type EGFR? Two Systematic Reviews and Meta-Analyses of Randomized Trials(...

por Vale, Claire L., Burdett, Sarah, Fisher, David J., Navani, Neal, Parmar, Mahesh K.B., Copas, Andrew J., Tierney, Jayne F.
Publicado 2015

Estimating the Impact of Randomised Control Trial Results on Clinical Practice: Results from a Survey and Modelling Study of Androgen Deprivation Therapy plus Radiotherapy for Loca...

por South, Annabelle, Parulekar, Wendy R., Sydes, Matthew R., Chen, Bingshu E., Parmar, Mahesh K., Clarke, Noel, Warde, Padraig, Mason, Malcolm
Publicado 2016

Mind the gap? The platform trial as a working environment

por Morrell, Liz, Hordern, Joshua, Brown, Louise, Sydes, Matthew R., Amos, Claire L., Kaplan, Richard S., Parmar, Mahesh K. B., Maughan, Timothy S.
Publicado 2019

Handling an uncertain control group event risk in non-inferiority trials: non-inferiority frontiers and the power-stabilising transformation

por Quartagno, Matteo, Walker, A. Sarah, Babiker, Abdel G., Turner, Rebecca M., Parmar, Mahesh K. B., Copas, Andrew, White, Ian R.
Publicado 2020

External data required timely response by the Trial Steering-Data Monitoring Committee for the NALoxone InVEstigation (N-ALIVE) pilot trial

por Bird, Sheila M., Strang, John, Ashby, Deborah, Podmore, John, Robertson, J. Roy, Welch, Sarah, Meade, Angela M., Parmar, Mahesh K.B.
Publicado 2017