The Multiple Sclerosis (MS) Genetic Risk Factors Indicate both Acquired and Innate Immune Cell Subsets Contribute to MS Pathogenesis and Identify Novel Therapeutic Opportunities

por Parnell, Grant P., Booth, David R.
Publicado 2017

The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities

por Afrasiabi, Ali, Ahlenstiel, Chantelle, Swaminathan, Sanjay, Parnell, Grant P
Publicado 2023

The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis

por Afrasiabi, Ali, Parnell, Grant P., Swaminathan, Sanjay, Stewart, Graeme J., Booth, David R.
Publicado 2020

Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk

por Ong, Lawrence T. C., Schibeci, Stephen D., Fewings, Nicole L., Booth, David R., Parnell, Grant P.
Publicado 2021

Differences in common heritable blood immune cell populations may underlie MS susceptibility and progression

por Booth, David R, Fewings, Nicole L, Parnell, Grant P, McKay, Fiona C, Stewart, Graeme J
Publicado 2016

Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein–Barr Virus hypomethylated regions

por Ong, Lawrence T. C., Parnell, Grant P., Afrasiabi, Ali, Stewart, Graeme J., Swaminathan, Sanjay, Booth, David R.
Publicado 2019

Gender and the Sex Hormone Estradiol Affect Multiple Sclerosis Risk Gene Expression in Epstein-Barr Virus-Infected B Cells

por Keane, Jeremy T., Afrasiabi, Ali, Schibeci, Stephen D., Fewings, Nicole, Parnell, Grant P., Swaminathan, Sanjay, Booth, David R.
Publicado 2021

The Interaction of Human and Epstein–Barr Virus miRNAs with Multiple Sclerosis Risk Loci

por Afrasiabi, Ali, Fewings, Nicole L., Schibeci, Stephen D., Keane, Jeremy T., Booth, David R., Parnell, Grant P., Swaminathan, Sanjay
Publicado 2021

A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia

por Parnell, Grant P, McLean, Anthony S, Booth, David R, Armstrong, Nicola J, Nalos, Marek, Huang, Stephen J, Manak, Jan, Tang, Wilson, Tam, Oi-Yan, Chan, Stanley, Tang, Benjamin M
Publicado 2012

Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility

por Afrasiabi, Ali, Parnell, Grant P., Fewings, Nicole, Schibeci, Stephen D., Basuki, Monica A., Chandramohan, Ramya, Zhou, Yuan, Taylor, Bruce, Brown, David A., Swaminathan, Sanjay, McKay, Fiona C., Stewart, Graeme J., Booth, David R.
Publicado 2019

Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions

por Law, Samantha P. L., Gatt, Prudence N., Schibeci, Stephen D., McKay, Fiona C., Vucic, Steve, Hart, Prue, Byrne, Scott N., Brown, David, Stewart, Graeme J., Liddle, Christopher, Parnell, Grant P., Booth, David R.
Publicado 2021

Neutrophils-related host factors associated with severe disease and fatality in patients with influenza infection

por Tang, Benjamin M., Shojaei, Maryam, Teoh, Sally, Meyers, Adrienne, Ho, John, Ball, T. Blake, Keynan, Yoav, Pisipati, Amarnath, Kumar, Aseem, Eisen, Damon P., Lai, Kevin, Gillett, Mark, Santram, Rahul, Geffers, Robert, Schreiber, Jens, Mozhui, Khyobeni, Huang, Stephen, Parnell, Grant P., Nalos, Marek, Holubova, Monika, Chew, Tracy, Booth, David, Kumar, Anand, McLean, Anthony, Schughart, Klaus
Publicado 2019

A community approach to mortality prediction in sepsis via gene expression analysis

por Sweeney, Timothy E., Perumal, Thanneer M., Henao, Ricardo, Nichols, Marshall, Howrylak, Judith A., Choi, Augustine M., Bermejo-Martin, Jesús F., Almansa, Raquel, Tamayo, Eduardo, Davenport, Emma E., Burnham, Katie L., Hinds, Charles J., Knight, Julian C., Woods, Christopher W., Kingsmore, Stephen F., Ginsburg, Geoffrey S., Wong, Hector R., Parnell, Grant P., Tang, Benjamin, Moldawer, Lyle L., Moore, Frederick E., Omberg, Larsson, Khatri, Purvesh, Tsalik, Ephraim L., Mangravite, Lara M., Langley, Raymond J.
Publicado 2018

Human anogenital monocyte-derived dendritic cells and langerin+cDC2 are major HIV target cells

por Rhodes, Jake W., Botting, Rachel A., Bertram, Kirstie M., Vine, Erica E., Rana, Hafsa, Baharlou, Heeva, Vegh, Peter, O’Neil, Thomas R., Ashhurst, Anneliese S., Fletcher, James, Parnell, Grant P., Graham, J. Dinny, Nasr, Najla, Lim, Jake J. K., Barnouti, Laith, Haertsch, Peter, Gosselink, Martijn P., Di Re, Angelina, Reza, Faizur, Ctercteko, Grahame, Jenkins, Gregory J., Brooks, Andrew J., Patrick, Ellis, Byrne, Scott N., Hunter, Eric, Haniffa, Muzlifah A., Cunningham, Anthony L., Harman, Andrew N.
Publicado 2021