Pharmacokinetics, Safety, and Tolerability of Tezepelumab (AMG 157) in Healthy and Atopic Dermatitis Adult Subjects

por Parnes, Jane R., Sullivan, John T., Chen, Li, Dias, Clapton
Publicado 2019

T Cell Receptor (TCR) Engagement Leads to Activation-induced Splicing of  Tumor Necrosis Factor (TNF) Nuclear Pre-mRNA

por Yang, Yang, Chang, Ju-Fay, Parnes, Jane R., Garrison Fathman, C.
Publicado 1998

Tezepelumab Reduces Exacerbations Across All Seasons in Patients with Severe, Uncontrolled Asthma: A Post Hoc Analysis of the PATHWAY Phase 2b Study

por Corren, Jonathan, Karpefors, Martin, Hellqvist, Åsa, Parnes, Jane R, Colice, Gene
Publicado 2021

Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma with and without Nasal Polyposis: A Post Hoc Analysis of the Phase 2b PATHWAY Study

por Emson, Claire, Corren, Jonathan, Sałapa, Kinga, Hellqvist, Åsa, Parnes, Jane R, Colice, Gene
Publicado 2021

Targeting TSLP in Asthma

por Parnes, Jane R, Molfino, Nestor A, Colice, Gene, Martin, Ubaldo, Corren, Jonathan, Menzies-Gow, Andrew
Publicado 2022

Baseline type 2 biomarker levels and response to tezepelumab in severe asthma

por Corren, Jonathan, Pham, Tuyet‐Hang, Garcia Gil, Esther, Sałapa, Kinga, Ren, Pin, Parnes, Jane R., Colice, Gene, Griffiths, Janet M.
Publicado 2022

CASCADE: a phase 2, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the effect of tezepelumab on airway inflammation in patients with uncontrolled as...

por Emson, Claire, Diver, Sarah, Chachi, Latifa, Megally, Ayman, Small, Cherrie, Downie, John, Parnes, Jane R., Bowen, Karin, Colice, Gene, Brightling, Chris E.
Publicado 2020

Reply to Lipworth and Chan

por Ambrose, Christopher S., Israel, Elliot, Bowen, Karin, Llanos, Jean-Pierre, Martin, Neil, Cook, Bill, Hellqvist, Åsa, Korn, Stephanie, Menzies-Gow, Andrew, Roseti, Stephanie L., Molfino, Nestor A., Griffiths, Janet M., Parnes, Jane R.
Publicado 2023

Safety and Biological Activity of Rozibafusp alfa, a Bispecific Inhibitor of Inducible Costimulator Ligand and B Cell Activating Factor, in Patients With Rheumatoid Arthritis: Resu...

por Abuqayyas, Lubna, Cheng, Laurence E., Teixeira dos Santos, Marcia, Sullivan, Barbara A., Ruiz‐Santiago, Norma, Wang, Hui, Zhou, Yanchen, Chindalore, Vishala, Cohen, Stanley, Kivitz, Alan J., Posch, Maximilian G., Parnes, Jane R.
Publicado 2022

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

por Oliveira, Marta I, Gonçalves, Carine M, Pinto, Mafalda, Fabre, Stéphanie, Santos, Ana Mafalda, Lee, Simon F, Castro, Mónica A A, Nunes, Raquel J, Barbosa, Rita R, Parnes, Jane R, Yu, Chao, Davis, Simon J, Moreira, Alexandra, Bismuth, Georges, Carmo, Alexandre M
Publicado 2012

Immune Complex Formation Is Associated With Loss of Tolerance and an Antibody Response to Both Drug and Target

por Kroenke, Mark A., Barger, Troy E., Hu, Jenny, Miller, Mieke Jill, Kalenian, Kevin, He, Lidong, Hsu, Hailing, Bartley, Yessenia, Chow, Vincent Fung-Sing, Teixeira dos Santos, Marcia Cristina, Sullivan, Barbara A., Cheng, Laurence E., Parnes, Jane R., Padaki, Rupa, Kuhns, Scott, Mytych, Daniel T.
Publicado 2021