Cdc45 is limiting for replication initiation in humans

por Köhler, Carsten, Koalick, Dennis, Fabricius, Anja, Parplys, Ann Christin, Borgmann, Kerstin, Pospiech, Helmut, Grosse, Frank
Publicado 2016

Exploiting Chromosomal Instability of PTEN-Deficient Triple-Negative Breast Cancer Cell Lines for the Sensitization Against PARP1 Inhibition in a Replication-Dependent Manner

por Rieckhoff, Johanna, Meyer, Felix, Classen, Sandra, Zielinski, Alexandra, Riepen, Britta, Wikman, Harriet, Petersen, Cordula, Rothkamm, Kai, Borgmann, Kerstin, Parplys, Ann Christin
Publicado 2020

Constitutive gp130 activation rapidly accelerates the transformation of human hepatocytes via an impaired oxidative stress response

por Heim, Denise, Gil-Ibanez, Ines, Herden, Johannes, Parplys, Ann Christin, Borgmann, Kerstin, Schmidt-Arras, Dirk, Lohse, Ansgar W., Rose-John, Stefan, Wege, Henning
Publicado 2016

Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines

por Subtil, Florentine S. B., Gröbner, Carolin, Recknagel, Niklas, Parplys, Ann Christin, Kohl, Sibylla, Arenz, Andrea, Eberle, Fabian, Dikomey, Ekkehard, Engenhart-Cabillic, Rita, Schötz, Ulrike
Publicado 2022

Prevention of DNA Replication Stress by CHK1 Leads to Chemoresistance Despite a DNA Repair Defect in Homologous Recombination in Breast Cancer

por Meyer, Felix, Becker, Saskia, Classen, Sandra, Parplys, Ann Christin, Mansour, Wael Yassin, Riepen, Britta, Timm, Sara, Ruebe, Claudia, Jasin, Maria, Wikman, Harriet, Petersen, Cordula, Rothkamm, Kai, Borgmann, Kerstin
Publicado 2020

Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients

por de Buhr, Nicole, Parplys, Ann Christin, Schroeder, Maria, Henneck, Timo, Schaumburg, Berfin, Stanelle-Bertram, Stephanie, Jarczak, Dominik, Nierhaus, Axel, Hiller, Jens, Peine, Sven, Kluge, Stefan, Klingel, Karin, Gabriel, Gülsah, von Köckritz-Blickwede, Maren
Publicado 2022

Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities

por Struve, Nina, Hoffer, Konstantin, Weik, Anna-Sophie, Riepen, Britta, Krug, Leonie, Cetin, Meryem H, Burmester, Jasmin, Ott, Leonie, Liebing, Jana, Gatzemeier, Fruzsina, Müller-Goebel, Justus, Gerbach, Mirja, Bußmann, Lara, Parplys, Ann Christin, Unger, Kristian, Mansour, Wael Y, Schüller, Ulrich, Rieckmann, Thorsten, Petersen, Cordula, Rothkamm, Kai, Short, Susan C, Kriegs, Malte
Publicado 2021