Therapeutic antibody engineering: Current and future advances driving the strongest growth area in the pharmaceutical industry

por Parren, Paul W.H.I., Lugovskoy, Alexey A.
Publicado 2013

The antiviral activity of antibodies in vitro and in vivo

por Parren, Paul W.H.I., Burton, Dennis R.
Publicado 2001

Fab-arm exchange: What’s in a name?

por Schuurman, Janine, Labrijn, Aran F., Parren, Paul W.H.I.
Publicado 2012

Changes to International Nonproprietary Names for antibody therapeutics 2017 and beyond: of mice, men and more

por Parren, Paul W. H. I., Carter, Paul J., Plückthun, Andreas
Publicado 2017

Avidity in antibody effector functions and biotherapeutic drug design

por Oostindie, Simone C., Lazar, Greg A., Schuurman, Janine, Parren, Paul W. H. I.
Publicado 2022

Editorial: Antibody Therapeutics for the Treatment of Filoviral Infection

por Murin, Charles D., Gunn, Bronwyn M., Parren, Paul W. H. I., Kobinger, Gary P.
Publicado 2022

High-Throughput Screening for Internalizing Antibodies by Homogeneous Fluorescence Imaging of a pH-Activated Probe

por Riedl, Thilo, van Boxtel, Egon, Bosch, Martijn, Parren, Paul W. H. I., Gerritsen, Arnout F.
Publicado 2016

Novel human antibody therapeutics: The age of the Umabs

por Ruuls, Sigrid R, van Bueren, Jeroen J Lammerts, van de Winkel, Jan G J, Parren, Paul W H I
Publicado 2008

Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor

por Bangsgaard, Nannie, Houtkamp, Mischa, Schuurhuis, Danita H., Parren, Paul W. H. I., Baadsgaard, Ole, Niessen, Hans W. M., Skov, Lone
Publicado 2012

Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry

por Wang, Guanbo, de Jong, Rob N., van den Bremer, Ewald T. J., Parren, Paul W. H. I., Heck, Albert J. R.
Publicado 2017

Inhibition of Virus Attachment to CD4(+) Target Cells Is a Major Mechanism of T Cell Line–adapted HIV-1 Neutralization

por Ugolini, Sophie, Mondor, Isabelle, Parren, Paul W.H.I., Burton, Dennis R., Tilley, Shermaine A., Klasse, Per Johan, Sattentau, Quentin J.
Publicado 1997

Neutralizing Antibody Fails to Impact the Course of Ebola Virus Infection in Monkeys

por Oswald, Wendelien B, Geisbert, Thomas W, Davis, Kelly J, Geisbert, Joan B, Sullivan, Nancy J, Jahrling, Peter B, Parren, Paul W. H. I, Burton, Dennis R
Publicado 2007

Gamma Delta T-Cell Based Cancer Immunotherapy: Past-Present-Future

por Saura-Esteller, José, de Jong, Milon, King, Lisa A., Ensing, Erik, Winograd, Benjamin, de Gruijl, Tanja D., Parren, Paul W. H. I., van der Vliet, Hans J.
Publicado 2022

Mutation of Y407 in the CH3 domain dramatically alters glycosylation and structure of human IgG

por Rose, Rebecca J., van Berkel, Patrick H.C., van den Bremer, Ewald T.J., Labrijn, Aran F., Vink, Tom, Schuurman, Janine, Heck, Albert J.R., Parren, Paul W.H.I.
Publicado 2013

Monoclonal antibodies targeting CD38 in hematological malignancies and beyond

por van de Donk, Niels W. C. J., Janmaat, Maarten L., Mutis, Tuna, Lammerts van Bueren, Jeroen J., Ahmadi, Tahamtan, Sasser, A. Kate, Lokhorst, Henk M., Parren, Paul W. H. I.
Publicado 2016

Efficient Generation of Bispecific Murine Antibodies for Pre-Clinical Investigations in Syngeneic Rodent Models

por Labrijn, Aran F., Meesters, Joyce I., Bunce, Matthew, Armstrong, Anthony A., Somani, Sandeep, Nesspor, Tom C., Chiu, Mark L., Altintaş, Işil, Verploegen, Sandra, Schuurman, Janine, Parren, Paul W. H. I.
Publicado 2017

Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET

por Neijssen, Joost, Cardoso, Rosa M.F., Chevalier, Kristen M., Wiegman, Luus, Valerius, Thomas, Anderson, G. Mark, Moores, Sheri L., Schuurman, Janine, Parren, Paul W.H.I., Strohl, William R., Chiu, Mark L.
Publicado 2021

Epidermal Growth Factor Receptor as Target for Perioperative Elimination of Circulating Colorectal Cancer Cells

por Gruijs, Mandy, Braster, Rens, Overdijk, Marije B., Hellingman, Tessa, Verploegen, Sandra, Korthouwer, Rianne, van der Wilk, Berend J., Parren, Paul W. H. I., van der Vliet, Hans J., Bögels, Marijn, van Egmond, Marjolein
Publicado 2022

A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface

por de Jong, Rob N., Beurskens, Frank J., Verploegen, Sandra, Strumane, Kristin, van Kampen, Muriel D., Voorhorst, Marleen, Horstman, Wendy, Engelberts, Patrick J., Oostindie, Simone C., Wang, Guanbo, Heck, Albert J. R., Schuurman, Janine, Parren, Paul W. H. I.
Publicado 2016

Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis

por Vergoossen, Dana L. E., Plomp, Jaap J., Gstöttner, Christoph, Fillié-Grijpma, Yvonne E., Augustinus, Roy, Verpalen, Robyn, Wuhrer, Manfred, Parren, Paul W. H. I., Dominguez-Vega, Elena, van der Maarel, Silvère M., Verschuuren, Jan J., Huijbers, Maartje G.
Publicado 2021