Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism

por Waraky, Ahmed, Akopyan, Karen, Parrow, Vendela, Strömberg, Thomas, Axelson, Magnus, Abrahmsén, Lars, Lindqvist, Arne, Larsson, Olle, Aleem, Eiman
Publicado 2014

Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

por Blom, Kristin, Rubin, Jenny, Berglund, Malin, Jarvius, Malin, Lenhammar, Lena, Parrow, Vendela, Andersson, Claes, Loskog, Angelica, Fryknäs, Mårten, Nygren, Peter, Larsson, Rolf
Publicado 2019

Mebendazole is unique among tubulin-active drugs in activating the MEK–ERK pathway

por Andersson, Claes R., Selvin, Tove, Blom, Kristin, Rubin, Jenny, Berglund, Malin, Jarvius, Malin, Lenhammar, Lena, Parrow, Vendela, Loskog, Angelica, Fryknäs, Mårten, Nygren, Peter, Larsson, Rolf
Publicado 2020

Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

por Bonagas, Nadilly, Gustafsson, Nina M. S., Henriksson, Martin, Marttila, Petra, Gustafsson, Robert, Wiita, Elisée, Borhade, Sanjay, Green, Alanna C., Vallin, Karl S. A., Sarno, Antonio, Svensson, Richard, Göktürk, Camilla, Pham, Therese, Jemth, Ann-Sofie, Loseva, Olga, Cookson, Victoria, Kiweler, Nicole, Sandberg, Lars, Rasti, Azita, Unterlass, Judith E., Haraldsson, Martin, Andersson, Yasmin, Scaletti, Emma R., Bengtsson, Christoffer, Paulin, Cynthia B. J., Sanjiv, Kumar, Abdurakhmanov, Eldar, Pudelko, Linda, Kunz, Ben, Desroses, Matthieu, Iliev, Petar, Färnegårdh, Katarina, Krämer, Andreas, Garg, Neeraj, Michel, Maurice, Häggblad, Sara, Jarvius, Malin, Kalderén, Christina, Jensen, Amanda Bögedahl, Almlöf, Ingrid, Karsten, Stella, Zhang, Si Min, Häggblad, Maria, Eriksson, Anders, Liu, Jianping, Glinghammar, Björn, Nekhotiaeva, Natalia, Klingegård, Fredrik, Koolmeister, Tobias, Martens, Ulf, Llona-Minguez, Sabin, Moulson, Ruth, Nordström, Helena, Parrow, Vendela, Dahllund, Leif, Sjöberg, Birger, Vargas, Irene L., Vo, Duy Duc, Wannberg, Johan, Knapp, Stefan, Krokan, Hans E., Arvidsson, Per I., Scobie, Martin, Meiser, Johannes, Stenmark, Pål, Berglund, Ulrika Warpman, Homan, Evert J., Helleday, Thomas
Publicado 2022