The impact of RNA sequence library construction protocols on transcriptomic profiling of leukemia

por Kumar, Ashwini, Kankainen, Matti, Parsons, Alun, Kallioniemi, Olli, Mattila, Pirkko, Heckman, Caroline A.
Publicado 2017

FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML

por Kivioja, Jarno, Malani, Disha, Kumar, Ashwini, Kontro, Mika, Parsons, Alun, Kallioniemi, Olli, Heckman, Caroline A.
Publicado 2021

Full-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Finnish Patients from 2009 to 2013

por Lakspere, Triin, Tynell, Janne, Kaloinen, Minttu, Vanlede, Maarten, Parsons, Alun, Ikonen, Niina, Kallio-Kokko, Hannimari, Kantele, Anu, Mattila, Pirkko, Almusa, Henrikki, Julkunen, Ilkka, Kainov, Denis, Kakkola, Laura
Publicado 2014

Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

por Kuusanmäki, Heikki, Dufva, Olli, Parri, Elina, van Adrichem, Arjan J., Rajala, Hanna, Majumder, Muntasir M., Yadav, Bhagwan, Parsons, Alun, Chan, Wing C., Wennerberg, Krister, Mustjoki, Satu, Heckman, Caroline A.
Publicado 2017

Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing

por Majumder, Muntasir Mamun, Silvennoinen, Raija, Anttila, Pekka, Tamborero, David, Eldfors, Samuli, Yadav, Bhagwan, Karjalainen, Riikka, Kuusanmäki, Heikki, Lievonen, Juha, Parsons, Alun, Suvela, Minna, Jantunen, Esa, Porkka, Kimmo, Heckman, Caroline A.
Publicado 2017

CKS1 inhibition reveals vulnerabilities in leukemic stem cells with concomitant protection of healthy hematopoietic stem cells

por Grey, William, Rio-Machin, Ana, Casado-Izquierdo, Pedro, Grönroos, Eva, Ali, Sara, Miettinen, Juho J., Bewicke-Copley, Findley, Parsons, Alun, Heckman, Caroline A., Swanton, Charles, Cutillas, Pedro, Gribben, John, Fitzgibbon, Jude, Bonnet, Dominique
Publicado 2022

S100 Calcium Binding Protein Family Members Associate With Poor Patient Outcome and Response to Proteasome Inhibition in Multiple Myeloma

por Liu, Minxia, Wang, Yinyin, Miettinen, Juho J., Kumari, Romika, Majumder, Muntasir Mamun, Tierney, Ciara, Bazou, Despina, Parsons, Alun, Suvela, Minna, Lievonen, Juha, Silvennoinen, Raija, Anttila, Pekka, Dowling, Paul, O’Gorman, Peter, Tang, Jing, Heckman, Caroline A.
Publicado 2021

Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes

por Casado, Pedro, Rio-Machin, Ana, Miettinen, Juho J., Bewicke-Copley, Findlay, Rouault-Pierre, Kevin, Krizsan, Szilvia, Parsons, Alun, Rajeeve, Vinothini, Miraki-Moud, Farideh, Taussig, David C., Bödör, Csaba, Gribben, John, Heckman, Caroline, Fitzgibbon, Jude, Cutillas, Pedro R.
Publicado 2023

Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types

por Majumder, Muntasir M., Leppä, Aino-Maija, Hellesøy, Monica, Dowling, Paul, Malyutina, Alina, Kopperud, Reidun, Bazou, Despina, Andersson, Emma, Parsons, Alun, Tang, Jing, Kallioniemi, Olli, Mustjoki, Satu, O’Gorman, Peter, Wennerberg, Krister, Porkka, Kimmo, Gjertsen, Bjørn T., Heckman, Caroline A.
Publicado 2020

Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma

por Bolomsky, Arnold, Miettinen, Juho J., Malyutina, Alina, Besse, Andrej, Huber, Julia, Fellinger, Stefanie, Breid, Helene, Parsons, Alun, Klavins, Kristaps, Hannich, J. Thomas, Kubicek, Stefan, Caers, Jo, Hübl, Wolfgang, Schreder, Martin, Zojer, Niklas, Driessen, Christoph, Tang, Jing, Besse, Lenka, Heckman, Caroline A., Ludwig, Heinz
Publicado 2021

Ex vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia

por Kuusanmäki, Heikki, Kytölä, Sari, Vänttinen, Ida, Ruokoranta, Tanja, Ranta, Amanda, Huuhtanen, Jani, Suvela, Minna, Parsons, Alun, Holopainen, Annasofia, Partanen, Anu, Kuusisto, Milla E.L., Koskela, Sirpa, Räty, Riikka, Itälä-Remes, Maija, Västrik, Imre, Dufva, Olli, Siitonen, Sanna, Porkka, Kimmo, Wennerberg, Krister, Heckman, Caroline A., Ettala, Pia, Pyörälä, Marja, Rimpiläinen, Johanna, Siitonen, Timo, Kontro, Mika
Publicado 2022

Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

por Malani, Disha, Kumar, Ashwini, Brück, Oscar, Kontro, Mika, Yadav, Bhagwan, Hellesøy, Monica, Kuusanmäki, Heikki, Dufva, Olli, Kankainen, Matti, Eldfors, Samuli, Potdar, Swapnil, Saarela, Jani, Turunen, Laura, Parsons, Alun, Västrik, Imre, Kivinen, Katja, Saarela, Janna, Räty, Riikka, Lehto, Minna, Wolf, Maija, Gjertsen, Bjorn Tore, Mustjoki, Satu, Aittokallio, Tero, Wennerberg, Krister, Heckman, Caroline A., Kallioniemi, Olli, Porkka, Kimmo
Publicado 2022