Motor abnormalities as a putative endophenotype for Autism Spectrum Disorders

por Esposito, Gianluca, Paşca, Sergiu P.
Publicado 2013

Imaging neuronal migration and network activity in human forebrain assembloids

por Birey, Fikri, Pașca, Sergiu P.
Publicado 2022

Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model

por Song, Ren, Pekrun, Katja, Khan, Themasap A., Zhang, Feijie, Paşca, Sergiu P., Kay, Mark A.
Publicado 2022

Timothy Syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons

por Krey, Jocelyn F., Pasca, Sergiu P., Shcheglovitov, Aleksandr, Yazawa, Masayuki, Schwemberger, Rachel, Rasmusson, Randall, Dolmetsch, Ricardo E.
Publicado 2013

Paraoxonase 1 activities and polymorphisms in autism spectrum disorders

por Paşca, Sergiu P, Dronca, Eleonora, Nemeş, Bogdan, Kaucsár, Tamás, Endreffy, Emõke, Iftene, Felicia, Benga, Ileana, Cornean, Rodica, Dronca, Maria
Publicado 2010

Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome

por Tian, Yuan, Voineagu, Irina, Paşca, Sergiu P, Won, Hyejung, Chandran, Vijayendran, Horvath, Steve, Dolmetsch, Ricardo E, Geschwind, Daniel H
Publicado 2014

A Promoter in the Coding Region of the Calcium Channel Gene CACNA1C Generates the Transcription Factor CCAT

por Gomez-Ospina, Natalia, Panagiotakos, Georgia, Portmann, Thomas, Pasca, Sergiu P., Rabah, Dania, Budzillo, Agata, Kinet, Jean Pierre, Dolmetsch, Ricardo E.
Publicado 2013

Differentiation and Maturation of Oligodendrocytes in Human Three-Dimensional Neural Cultures

por Marton, Rebecca M., Miura, Yuki, Sloan, Steven A., Li, Qingyun, Revah, Omer, Levy, Rebecca J., Huguenard, John R., Pașca, Sergiu P.
Publicado 2019

Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome

por Panagiotakos, Georgia, Haveles, Christos, Arjun, Arpana, Petrova, Ralitsa, Rana, Anshul, Portmann, Thomas, Paşca, Sergiu P, Palmer, Theo D, Dolmetsch, Ricardo E
Publicado 2019

Spatially controlled construction of assembloids using bioprinting

por Roth, Julien G., Brunel, Lucia G., Huang, Michelle S., Liu, Yueming, Cai, Betty, Sinha, Sauradeep, Yang, Fan, Pașca, Sergiu P., Shin, Sungchul, Heilshorn, Sarah C.
Publicado 2023

One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders

por Paşca, Sergiu P, Dronca, Eleonora, Kaucsár, Tamás, Crǎciun, Elena C, Endreffy, Emõke, Ferencz, Beatrix K, Iftene, Felicia, Benga, Ileana, Cornean, Rodica, Banerjee, Ruma, Dronca, Maria
Publicado 2009

Human 3D Cellular Model of Hypoxic Brain Injury of Prematurity

por Paşca, Anca M., Park, Jin-Young, Shin, Hyun-Woo, Qi, Qihao, Revah, Omer, Krasnoff, Rebecca, O’Hara, Ruth, Willsey, A. Jeremy, Palmer, Theo D., Paşca, Sergiu P.
Publicado 2019

Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells

por Miura, Yuki, Li, Min-Yin, Birey, Fikri, Ikeda, Kazuya, Revah, Omer, Thete, Mayuri Vijay, Park, Jin-Young, Puno, Alyssa, Lee, Samuel H., Porteus, Matthew H., Pașca, Sergiu P.
Publicado 2020

Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain

por Deverman, Benjamin E., Pravdo, Piers L., Simpson, Bryan P., Kumar, Sripriya Ravindra, Chan, Ken Y., Banerjee, Abhik, Wu, Wei-Li, Yang, Bin, Huber, Nina, Pasca, Sergiu P., Gradinaru, Viviana
Publicado 2016

Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment

por Meng, Xiangling, Yao, David, Imaizumi, Kent, Chen, Xiaoyu, Kelley, Kevin W., Reis, Noah, Thete, Mayuri Vijay, Arjun McKinney, Arpana, Kulkarni, Shravanti, Panagiotakos, Georgia, Bassik, Michael C., Pașca, Sergiu P.
Publicado 2023

Long Term Maturation of Human Cortical Organoids Matches Key Early Postnatal Transitions

por Gordon, Aaron, Yoon, Se-Jin, Tran, Stephen S., Makinson, Christopher D., Park, Jin Young, Andersen, Jimena, Valencia, Alfredo M., Horvath, Steve, Xiao, Xinshu, Huguenard, John R., Pașca, Sergiu P., Geschwind, Daniel H.
Publicado 2021

Using iPS cell-derived neurons to uncover cellular phenotypes associated with Timothy Syndrome

por Paşca, Sergiu P., Portmann, Thomas, Voineagu, Irina, Yazawa, Masayuki, Shcheglovitov, Oleksandr, Paşca, Anca M., Cord, Branden, Palmer, Theo D., Chikahisa, Sachiko, Seiji, Nishino, Bernstein, Jonathan A., Hallmayer, Joachim, Geschwind, Daniel H., Dolmetsch, Ricardo E.
Publicado 2011

Reliability of human 3D cortical organoid generation

por Yoon, Se-Jin, Elahi, Lubayna S., Pașca, Anca M., Marton, Rebecca M., Gordon, Aaron, Revah, Omer, Miura, Yuki, Walczak, Elisabeth M., Holdgate, Gwendolyn M., Fan, H. Christina, Huguenard, John R., Geschwind, Daniel H., Pașca, Sergiu P.
Publicado 2018

Assembly of functionally integrated human forebrain spheroids

por Birey, Fikri, Andersen, Jimena, Makinson, Christopher D., Islam, Saiful, Wei, Wu, Huber, Nina, Fan, H. Christina, Cordes Metzler, Kimberly R., Panagiotakos, Georgia, Thom, Nicholas, O’Rourke, Nancy A., Steinmetz, Lars M., Bernstein, Jonathan A., Hallmayer, Joachim, Huguenard, John R., Pașca, Sergiu P.
Publicado 2017

A deleterious Na(v)1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients

por Sun, Yishan, Paşca, Sergiu P, Portmann, Thomas, Goold, Carleton, Worringer, Kathleen A, Guan, Wendy, Chan, Karen C, Gai, Hui, Vogt, Daniel, Chen, Ying-Jiun J, Mao, Rong, Chan, Karrie, Rubenstein, John LR, Madison, Daniel V, Hallmayer, Joachim, Froehlich-Santino, Wendy M, Bernstein, Jonathan A, Dolmetsch, Ricardo E
Publicado 2016