Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis

por Passariello, Margherita, Vetrei, Cinzia, Amato, Felice, De Lorenzo, Claudia
Publicado 2021

Novel Human Bispecific Aptamer–Antibody Conjugates for Efficient Cancer Cell Killing

por Passariello, Margherita, Camorani, Simona, Vetrei, Cinzia, Cerchia, Laura, De Lorenzo, Claudia
Publicado 2019

Ipilimumab and Its Derived EGFR Aptamer-Based Conjugate Induce Efficient NK Cell Activation against Cancer Cells

por Passariello, Margherita, Camorani, Simona, Vetrei, Cinzia, Ricci, Stefania, Cerchia, Laura, De Lorenzo, Claudia
Publicado 2020

A Comparison of the Antitumor Efficacy of Novel Multi-Specific Tribodies with Combinations of Approved Immunomodulatory Antibodies

por Manna, Lorenzo, Rapuano Lembo, Rosa, Yoshioka, Asami, Nakamura, Koji, Passariello, Margherita, De Lorenzo, Claudia
Publicado 2023

Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

por Vetrei, Cinzia, Passariello, Margherita, Froechlich, Guendalina, Rapuano Lembo, Rosa, Zambrano, Nicola, De Lorenzo, Claudia
Publicado 2021

New Insights on the Role of Anti-PD-L1 and Anti-CTLA-4 mAbs on Different Lymphocytes Subpopulations in TNBC

por Lembo, Rosa Rapuano, Manna, Lorenzo, Froechlich, Guendalina, Sasso, Emanuele, Passariello, Margherita, De Lorenzo, Claudia
Publicado 2022

Novel Combinations of Human Immunomodulatory mAbs Lacking Cardiotoxic Effects for Therapy of TNBC

por Vetrei, Cinzia, Passariello, Margherita, Froechlich, Guendalina, Rapuano Lembo, Rosa, Sasso, Emanuele, Zambrano, Nicola, De Lorenzo, Claudia
Publicado 2021

Novel tri-specific tribodies induce strong T cell activation and anti-tumor effects in vitro and in vivo

por Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Inoue, Toshikazu, Nakamura, Koji, De Lorenzo, Claudia
Publicado 2022

A long non-coding SINEUP RNA boosts semi-stable production of fully human monoclonal antibodies in HEK293E cells

por Sasso, Emanuele, Latino, Debora, Froechlich, Guendalina, Succoio, Mariangela, Passariello, Margherita, De Lorenzo, Claudia, Nicosia, Alfredo, Zambrano, Nicola
Publicado 2018

Comparative Analysis of a Human Neutralizing mAb Specific for SARS-CoV-2 Spike-RBD with Cilgavimab and Tixagevimab for the Efficacy on the Omicron Variant in Neutralizing and Detec...

por Passariello, Margherita, Esposito, Speranza, Manna, Lorenzo, Rapuano Lembo, Rosa, Zollo, Immacolata, Sasso, Emanuele, Amato, Felice, De Lorenzo, Claudia
Publicado 2023

High-Throughput Monoclonal Antibody Discovery from Phage Libraries: Challenging the Current Preclinical Pipeline to Keep the Pace with the Increasing mAb Demand

por Zambrano, Nicola, Froechlich, Guendalina, Lazarevic, Dejan, Passariello, Margherita, Nicosia, Alfredo, De Lorenzo, Claudia, Morelli, Marco J., Sasso, Emanuele
Publicado 2022

Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling

por Passariello, Margherita, D’Alise, Anna Morena, Esposito, Annachiara, Vetrei, Cinzia, Froechlich, Guendalina, Scarselli, Elisa, Nicosia, Alfredo, De Lorenzo, Claudia
Publicado 2019

Novel Bi-Specific Immuno-Modulatory Tribodies Potentiate T Cell Activation and Increase Anti-Tumor Efficacy

por Passariello, Margherita, Yoshioka, Asami, Takahashi, Kota, Hashimoto, Shu-ichi, Rapuano Lembo, Rosa, Manna, Lorenzo, Nakamura, Koji, De Lorenzo, Claudia
Publicado 2022

Evidences of CTLA-4 and PD-1 Blocking Agents-Induced Cardiotoxicity in Cellular and Preclinical Models

por Quagliariello, Vincenzo, Passariello, Margherita, Rea, Domenica, Barbieri, Antonio, Iovine, Martina, Bonelli, Annamaria, Caronna, Antonietta, Botti, Gerardo, De Lorenzo, Claudia, Maurea, Nicola
Publicado 2020

A Novel Human Neutralizing mAb Recognizes Delta, Gamma and Omicron Variants of SARS-CoV-2 and Can Be Used in Combination with Sotrovimab

por Passariello, Margherita, Ferrucci, Veronica, Sasso, Emanuele, Manna, Lorenzo, Lembo, Rosa Rapuano, Pascarella, Stefano, Fusco, Giovanna, Zambrano, Nicola, Zollo, Massimo, De Lorenzo, Claudia
Publicado 2022

Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells

por Passariello, Margherita, Vetrei, Cinzia, Sasso, Emanuele, Froechlich, Guendalina, Gentile, Chiara, D’Alise, Anna Morena, Zambrano, Nicola, Scarselli, Elisa, Nicosia, Alfredo, De Lorenzo, Claudia
Publicado 2020

Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2

por Passariello, Margherita, Gentile, Chiara, Ferrucci, Veronica, Sasso, Emanuele, Vetrei, Cinzia, Fusco, Giovanna, Viscardi, Maurizio, Brandi, Sergio, Cerino, Pellegrino, Zambrano, Nicola, Zollo, Massimo, De Lorenzo, Claudia
Publicado 2021

Oncolytic Adenoviral Vector-Mediated Expression of an Anti-PD-L1-scFv Improves Anti-Tumoral Efficacy in a Melanoma Mouse Model

por Vitale, Maria, Scialò, Filippo, Passariello, Margherita, Leggiero, Eleonora, D’Agostino, Anna, Tripodi, Lorella, Gentile, Laura, Bianco, Andrea, Castaldo, Giuseppe, Cerullo, Vincenzo, De Lorenzo, Claudia, Pastore, Lucio
Publicado 2022

Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer

por Camorani, Simona, Passariello, Margherita, Agnello, Lisa, Esposito, Silvia, Collina, Francesca, Cantile, Monica, Di Bonito, Maurizio, Ulasov, Ilya V., Fedele, Monica, Zannetti, Antonella, De Lorenzo, Claudia, Cerchia, Laura
Publicado 2020

Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies

por Sasso, Emanuele, D’Avino, Chiara, Passariello, Margherita, D’Alise, Anna Morena, Siciliano, Daniela, Esposito, Maria Luisa, Froechlich, Guendalina, Cortese, Riccardo, Scarselli, Elisa, Zambrano, Nicola, Nicosia, Alfredo, De Lorenzo, Claudia
Publicado 2018