A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Phase I Study of Analgesic/Antihyperalgesic Properties of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in...

por Schaffler, Klaus, Yassen, Ashraf, Reeh, Peter, Passier, Paul
Publicado 2018

Pharmacodynamic analysis of the analgesic effect of capsaicin 8% patch (Qutenza™) in diabetic neuropathic pain patients: detection of distinct response groups

por Martini, Christian, Yassen, Ashraf, Olofsen, Erik, Passier, Paul, Stoker, Malcom, Dahan, Albert
Publicado 2012

A Phase I, Randomized, Double-Blind, Laser-Evoked Potential Study to Evaluate the Analgesic/Antihyperalgesic Effect of ASP9226, a State-Dependent N-Type Voltage-Gated Calcium Chann...

por Schaffler, Klaus, He, Weizhong, Passier, Paul, Tracy, Katherine, Fakhoury, Allam, Paul, Jeffrey
Publicado 2018

A Cocktail Interaction Study Evaluating the Drug‐Drug Interaction Potential of the Perpetrator Drug ASP8477 at Multiple Ascending Dose Levels

por Treijtel, Nicoline, Collins, Christiane, van Bruijnsvoort, Michel, Fuhr, Rainard, Ernault, Etienne, Gangaram‐Panday, Shanti, Passier, Paul
Publicado 2019

How to Successfully Generate an Alternative Approach to a Thorough QT Study: GLPG1972 as an Example

por Meyer, Claudia, Dierick, Ines, Gauderat, Glenn, Langenhorst, Jurgen, Sarr, Céline, Leroux, Emilie, Chenel, Marylore, Fouliard, Sylvain, Passier, Paul
Publicado 2022

Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale

por Bonate, Peter L., Wang, Tianli, Passier, Paul, Bagchus, Wilhelmina, Burt, Howard, Lüpfert, Christian, Abla, Nada, Kovac, Jana, Keiser, Jennifer
Publicado 2018

Safety, Pharmacokinetics, and Pharmacodynamics of the ADAMTS‐5 Inhibitor GLPG1972/S201086 in Healthy Volunteers and Participants With Osteoarthritis of the Knee or Hip

por van der Aar, Ellen, Deckx, Henri, Dupont, Sonia, Fieuw, Ann, Delage, Stephane, Larsson, Staffan, Struglics, André, Lohmander, L. Stefan, Lalande, Agnes, Leroux, Emilie, Amantini, David, Passier, Paul
Publicado 2021

Phase 1 and 2 Randomized Clinical Studies Determine Lack of Efficacy for Anti-IL-17C Antibody MOR106 in Moderate–Severe Atopic Dermatitis

por Thaçi, Diamant, Singh, Dave, Lee, Mark, Timmis, Helen, Jacobs, Dominique, Passier, Paul, Rohrer, Susanne, Beetens, Johan, Phung, De, Sondag, Eric, Babic, Goran, Würth, Guido, Kloepfer, Pia, Härtle, Stefan, Hüttner, Silke
Publicado 2022