The Impact of Next Generation Sequencing in Cancer Research

por Nones, Katia, Patch, Ann-Marie
Publicado 2020

Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis

por Fennell, Lochlan J., Hartel, Gunter, McKeone, Diane M., Bond, Catherine E., Kane, Alexandra, Leggett, Barbara A., Patch, Ann-Marie, Whitehall, Vicki L.J.
Publicado 2022

Genome-Wide Homozygosity Analysis Reveals HADH Mutations as a Common Cause of Diazoxide-Responsive Hyperinsulinemic-Hypoglycemia in Consanguineous Pedigrees

por Flanagan, Sarah E., Patch, Ann-Marie, Locke, Jonathan M., Akcay, Teoman, Simsek, Enver, Alaei, Mohammadreza, Yekta, Zeinab, Desai, Meena, Kapoor, Ritika R., Hussain, Khalid, Ellard, Sian
Publicado 2011

Homozygosity mapping provides supporting evidence of pathogenicity in recessive Mendelian disease

por Wakeling, Matthew Neil, Laver, Thomas William, Wright, Caroline Fiona, De Franco, Elisa, Stals, Karen Lucy, Patch, Ann-Marie, Hattersley, Andrew Tym, Flanagan, Sarah Elizabeth, Ellard, Sian
Publicado 2018

Correction: Homozygosity mapping provides supporting evidence of pathogenicity in recessive Mendelian disease

por Wakeling, Matthew Neil, Laver, Thomas William, Wright, Caroline Fiona, De Franco, Elisa, Stals, Karen Lucy, Patch, Ann-Marie, Hattersley, Andrew Tym, Flanagan, Sarah Elizabeth, Ellard, Sian
Publicado 2018

In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets

por Piper Hanley, Karen, Hearn, Tom, Berry, Andrew, Carvell, Melanie J, Patch, Ann-Marie, Williams, Louise J, Sugden, Sarah A, Wilson, David I, Ellard, Sian, Hanley, Neil A
Publicado 2010

Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma

por Sneddon, Sophie, Patch, Ann-Marie, Dick, Ian M., Kazakoff, Stephen, Pearson, John V., Waddell, Nicola, Allcock, Richard J. N., Holt, Robert A., Robinson, Bruce W. S., Creaney, Jenette
Publicado 2017

Intratumoural Heterogeneity Underlies Distinct Therapy Responses and Treatment Resistance in Glioblastoma

por Akgül, Seçkin, Patch, Ann-Marie, D’Souza, Rochelle C.J., Mukhopadhyay, Pamela, Nones, Katia, Kempe, Sarah, Kazakoff, Stephen H., Jeffree, Rosalind L., Stringer, Brett W., Pearson, John V., Waddell, Nicola, Day, Bryan W.
Publicado 2019

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

por Kane, Alexandra M., Fennell, Lochlan J., Liu, Cheng, Borowsky, Jennifer, McKeone, Diane M., Bond, Catherine E., Kazakoff, Stephen, Patch, Ann-Marie, Koufariotis, Lambros T., Pearson, John, Waddell, Nicola, Leggett, Barbara A., Whitehall, Vicki L.J.
Publicado 2020

Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures

por Hazlewood, Jessamine E., Dumenil, Troy, Le, Thuy T., Slonchak, Andrii, Kazakoff, Stephen H., Patch, Ann-Marie, Gray, Lesley-Ann, Howley, Paul M., Liu, Liang, Hayball, John D., Yan, Kexin, Rawle, Daniel J., Prow, Natalie A., Suhrbier, Andreas
Publicado 2021

APC Mutation Marks an Aggressive Subtype of BRAF Mutant Colorectal Cancers

por Fennell, Lochlan J., Kane, Alexandra, Liu, Cheng, McKeone, Diane, Fernando, Winnie, Su, Chang, Bond, Catherine, Jamieson, Saara, Dumenil, Troy, Patch, Ann-Marie, Kazakoff, Stephen H., Pearson, John V., Waddell, Nicola, Leggett, Barbara, Whitehall, Vicki L. J.
Publicado 2020

Cre recombinase expression cooperates with homozygous FLT3 internal tandem duplication knockin mouse model to induce acute myeloid leukemia

por Straube, Jasmin, Eifert, Theresa, Vu, Therese, Janardhanan, Yashaswini, Haldar, Rohit, von Eyss, Björn, Cooper, Leanne, Bruedigam, Claudia, Ling, Victoria Y., Cooper, Emily, Patch, Ann-Marie, Bullinger, Lars, Schnoeder, Tina M., Bywater, Megan, Heidel, Florian H., Lane, Steven W.
Publicado 2023

qmotif: determination of telomere content from whole-genome sequence data

por Holmes, Oliver, Nones, Katia, Tang, Yue Hang, Loffler, Kelly A, Lee, Michael, Patch, Ann-Marie, Dagg, Rebecca A, Lau, Loretta M S, Leonard, Conrad, Wood, Scott, Xu, Qinying, Pickett, Hilda A, Reddel, Roger R, Barbour, Andrew P, Grimmond, Sean M, Waddell, Nicola, Pearson, John V
Publicado 2022

Analysis of Transcription Factors Key for Mouse Pancreatic Development Establishes NKX2-2 and MNX1 Mutations as Causes of Neonatal Diabetes in Man

por Flanagan, Sarah E., De Franco, Elisa, Lango Allen, Hana, Zerah, Michele, Abdul-Rasoul, Majedah M., Edge, Julie A., Stewart, Helen, Alamiri, Elham, Hussain, Khalid, Wallis, Sam, de Vries, Liat, Rubio-Cabezas, Oscar, Houghton, Jayne A.L., Edghill, Emma L., Patch, Ann-Marie, Ellard, Sian, Hattersley, Andrew T.
Publicado 2014

Copy number profiles of paired primary and metastatic colorectal cancers

por Kawamata, Futoshi, Patch, Ann-Marie, Nones, Katia, Bond, Catherine, McKeone, Diane, Pearson, Sally-Ann, Homma, Shigenori, Liu, Cheng, Fennell, Lochlan, Dumenil, Troy, Hartel, Gunter, Kobayasi, Nozomi, Yokoo, Hideki, Fukai, Moto, Nishihara, Hiroshi, Kamiyama, Toshiya, Burge, Matthew E., Karapetis, Christos S., Taketomi, Akinobu, Leggett, Barbara, Waddell, Nicola, Whitehall, Vicki
Publicado 2017

Complex structural rearrangements are present in high-grade dysplastic Barrett’s oesophagus samples

por Newell, Felicity, Patel, Kalpana, Gartside, Michael, Krause, Lutz, Brosda, Sandra, Aoude, Lauren G., Loffler, Kelly A., Bonazzi, Vanessa F., Patch, Ann-Marie, Kazakoff, Stephen H., Holmes, Oliver, Xu, Qinying, Wood, Scott, Leonard, Conrad, Lampe, Guy, Lord, Reginald V., Whiteman, David C., Pearson, John V., Nones, Katia, Waddell, Nicola, Barbour, Andrew P.
Publicado 2019

Discrepancies in tumor mutation burden reporting from sequential endobronchial ultrasound transbronchial needle aspiration samples within single lymph node stations - brief report

por Fielding, David, Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Lakis, Vanessa, Chittoory, Haarika, Fairbairn, David, Patch, Ann-Marie, Kazakoff, Stephen H., Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Ryan, Kimberley, Hodgson, Alan, Sharma, Sowmya, Pearson, John V., Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter, Simpson, Peter T., Nones, Katia
Publicado 2023

Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis

por Weedon, Michael N., Cebola, Ines, Patch, Ann-Marie, Flanagan, Sarah E., De Franco, Elisa, Caswell, Richard, Rodríguez-Seguí, Santiago A., Shaw-Smith, Charles, Cho, Candy H-H., Allen, Hana Lango, Houghton, Jayne AL., Roth, Christian L., Chen, Rongrong, Hussain, Khalid, Marsh, Phil, Vallier, Ludovic, Murray, Anna, Ellard, Sian, Ferrer, Jorge, Hattersley, Andrew T.
Publicado 2013

Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas

por Fennell, Lochlan, Dumenil, Troy, Wockner, Leesa, Hartel, Gunter, Nones, Katia, Bond, Catherine, Borowsky, Jennifer, Liu, Cheng, McKeone, Diane, Bowdler, Lisa, Montgomery, Grant, Klein, Kerenaftali, Hoffmann, Isabell, Patch, Ann-Marie, Kazakoff, Stephen, Pearson, John, Waddell, Nicola, Wirapati, Pratyaksha, Lochhead, Paul, Imamura, Yu, Ogino, Shuji, Shao, Renfu, Tejpar, Sabine, Leggett, Barbara, Whitehall, Vicki
Publicado 2019

Telomere sequence content can be used to determine ALT activity in tumours

por Lee, Michael, Teber, Erdahl T, Holmes, Oliver, Nones, Katia, Patch, Ann-Marie, Dagg, Rebecca A, Lau, Loretta M S, Lee, Joyce H, Napier, Christine E, Arthur, Jonathan W, Grimmond, Sean M, Hayward, Nicholas K, Johansson, Peter A, Mann, Graham J, Scolyer, Richard A, Wilmott, James S, Reddel, Roger R, Pearson, John V, Waddell, Nicola, Pickett, Hilda A
Publicado 2018