Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A

por Damai, Margarita, Guzzardi, Norman, Lewis, Viliyana, Rao, Zenobia X., Sykes, Daniel, Patel, Bhaven
Publicado 2023

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens

por Patel, Bhaven B., Lebensohn, Andres M., Pusapati, Ganesh V., Carette, Jan E., Salzman, Julia, Rohatgi, Rajat
Publicado 2019

CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog

por Pusapati, Ganesh V., Kong, Jennifer H., Patel, Bhaven B., Krishnan, Arunkumar, Sagner, Andreas, Kinnebrew, Maia, Briscoe, James, Aravind, L., Rohatgi, Rajat
Publicado 2018

Direct ionic stress sensing and mitigation by the transcription factor NFAT5

por Khandwala, Chandni B., Sarkar, Parijat, Schmidt, H. Broder, Ma, Mengxiao, Kinnebrew, Maia, Pusapati, Ganesh V., Patel, Bhaven B., Tillo, Desiree, Lebensohn, Andres M., Rohatgi, Rajat
Publicado 2023

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling

por Kinnebrew, Maia, Iverson, Ellen J, Patel, Bhaven B, Pusapati, Ganesh V, Kong, Jennifer H, Johnson, Kristen A, Luchetti, Giovanni, Eckert, Kaitlyn M, McDonald, Jeffrey G, Covey, Douglas F, Siebold, Christian, Radhakrishnan, Arun, Rohatgi, Rajat
Publicado 2019

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

por Lebensohn, Andres M, Dubey, Ramin, Neitzel, Leif R, Tacchelly-Benites, Ofelia, Yang, Eungi, Marceau, Caleb D, Davis, Eric M, Patel, Bhaven B, Bahrami-Nejad, Zahra, Travaglini, Kyle J, Ahmed, Yashi, Lee, Ethan, Carette, Jan E, Rohatgi, Rajat
Publicado 2016

Gene-teratogen interactions influence the penetrance of birth defects by altering Hedgehog signaling strength

por Kong, Jennifer H., Young, Cullen B., Pusapati, Ganesh V., Espinoza, F. Hernán, Patel, Chandni B., Beckert, Francis, Ho, Sebastian, Patel, Bhaven B., Gabriel, George C., Aravind, L., Bazan, J. Fernando, Gunn, Teresa M., Lo, Cecilia W., Rohatgi, Rajat
Publicado 2021