That’s a Wrap: Could Controlling Activity-Regulated Myelination Prevent Absence Seizures?

por Miralles, Raquel, Patel, Manoj K.
Publicado 2022

Waiting to Inhale: Preventing Fatality From Seizure-Induced Apnea

por Wenker, Ian C., Patel, Manoj K.
Publicado 2023

The Role of the Persistent Sodium Current in Epilepsy

por Wengert, Eric R., Patel, Manoj K.
Publicado 2020

One Size Doesn’t Fit All: Variant-Specific Effects in SCN8A Encephalopathy

por Wengert, Eric R., Patel, Manoj K.
Publicado 2021

It Takes Two to Tango: Channel Interplay Leads to Paradoxical Hyperexcitability in a Loss-of-Function Epilepsy Variant

por Miralles, Raquel M., Patel, Manoj K.
Publicado 2021

Carbon Dots Conjugated Antibody as an Effective FRET-Based Biosensor for Progesterone Hormone Screening

por Disha, Kumari, Poonam, Patel, Manoj K., Kumar, Parveen, Nayak, Manoj K.
Publicado 2022

Peri-Ictal Autonomic Control of Cardiac Function and Seizure-Induced Death

por Wenker, Ian C., Blizzard, Elizabeth A., Wagley, Pravin K., Patel, Manoj K.
Publicado 2022

Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy

por Thompson, Jeremy A., Miralles, Raquel M., Wengert, Eric R., Wagley, Pravin K., Yu, Wenxi, Wenker, Ian C., Patel, Manoj K.
Publicado 2022

Forebrain epileptiform activity is not required for seizure-induced apnea in a mouse model of Scn8a epilepsy

por Wenker, Ian C., Boscia, Alexis R., Lewis, Christine, Tariq, Anas, Miralles, Raquel, Hanflink, Jessica C., Saraf, Priyanka, Patel, Manoj K.
Publicado 2022

Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of SCN8A Encephalopathy

por Wengert, Eric R., Wenker, Ian C., Wagner, Elizabeth L., Wagley, Pravin K., Gaykema, Ronald P., Shin, Jung-Bum, Patel, Manoj K.
Publicado 2021

Loss-of-function variants of SCN8A in intellectual disability without seizures

por Wagnon, Jacy L., Barker, Bryan S., Ottolini, Matteo, Park, Young, Volkheimer, Alicia, Valdez, Purnima, Swinkels, Marielle E.M., Patel, Manoj K., Meisler, Miriam H.
Publicado 2017

EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications

por Burke, Cassidy T., Vitko, Iuliia, Straub, Justyna, Nylund, Elsa O., Gawda, Agnieszka, Blair, Kathryn, Sullivan, Kyle A., Ergun, Lara, Ottolini, Matteo, Patel, Manoj K., Perez-Reyes, Edward
Publicado 2023

Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathy

por Wagnon, Jacy L., Barker, Bryan S., Hounshell, James A., Haaxma, Charlotte A., Shealy, Amy, Moss, Timothy, Parikh, Sumit, Messer, Ricka D., Patel, Manoj K., Meisler, Miriam H.
Publicado 2015

Partial loss‐of‐function of sodium channel SCN8A in familial isolated myoclonus

por Wagnon, Jacy L., Mencacci, Niccolò E., Barker, Bryan S., Wengert, Eric R., Bhatia, Kailash P., Balint, Bettina, Carecchio, Miryam, Wood, Nicholas W., Patel, Manoj K., Meisler, Miriam H.
Publicado 2018

Activation of Pyramidal Neurons in Mouse Medial Prefrontal Cortex Enhances Food-Seeking Behavior While Reducing Impulsivity in the Absence of an Effect on Food Intake

por Warthen, Daniel M., Lambeth, Philip S., Ottolini, Matteo, Shi, Yingtang, Barker, Bryan Scot, Gaykema, Ronald P., Newmyer, Brandon A., Joy-Gaba, Jonathan, Ohmura, Yu, Perez-Reyes, Edward, Güler, Ali D., Patel, Manoj K., Scott, Michael M.
Publicado 2016

Genetically targeted magnetic control of the nervous system

por Wheeler, Michael A., Smith, Cody J., Ottolini, Matteo, Barker, Bryan S., Purohit, Aarti M., Grippo, Ryan M., Gaykema, Ronald P., Spano, Anthony J., Beenhakker, Mark P., Kucenas, Sarah, Patel, Manoj K., Deppmann, Christopher D., Güler, Ali D.
Publicado 2016

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

por Alexandrou, Aristos J., Brown, Adam R., Chapman, Mark L., Estacion, Mark, Turner, Jamie, Mis, Malgorzata A., Wilbrey, Anna, Payne, Elizabeth C., Gutteridge, Alex, Cox, Peter J., Doyle, Rachel, Printzenhoff, David, Lin, Zhixin, Marron, Brian E., West, Christopher, Swain, Nigel A., Storer, R. Ian, Stupple, Paul A., Castle, Neil A., Hounshell, James A., Rivara, Mirko, Randall, Andrew, Dib-Hajj, Sulayman D., Krafte, Douglas, Waxman, Stephen G., Patel, Manoj K., Butt, Richard P., Stevens, Edward B.
Publicado 2016