HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site...

por Wang, Hao, Jurado, Kellie A., Wu, Xiaolin, Shun, Ming-Chieh, Li, Xiang, Ferris, Andrea L., Smith, Steven J., Patel, Pratiq A., Fuchs, James R., Cherepanov, Peter, Kvaratskhelia, Mamuka, Hughes, Stephen H., Engelman, Alan
Publicado 2012

The mechanism of H171T resistance reveals the importance of N(δ)-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase

por Slaughter, Alison, Jurado, Kellie A, Deng, Nanjie, Feng, Lei, Kessl, Jacques J, Shkriabai, Nikoloz, Larue, Ross C, Fadel, Hind J, Patel, Pratiq A, Jena, Nivedita, Fuchs, James R, Poeschla, Eric, Levy, Ronald M, Engelman, Alan, Kvaratskhelia, Mamuka
Publicado 2014