Toward a Rapid Production of Multivirus-Specific T Cells Targeting BKV, Adenovirus, CMV, and EBV from Umbilical Cord Blood

por Dave, Hema, Luo, Min, Blaney, J.W., Patel, Shabnum, Barese, Cecilia, Cruz, Conrad Russell, Shpall, Elizabeth J., Bollard, Catherine M., Hanley, Patrick J.
Publicado 2017

Beyond CAR T Cells: Other Cell-Based Immunotherapeutic Strategies Against Cancer

por Patel, Shabnum, Burga, Rachel A., Powell, Allison B., Chorvinsky, Elizabeth A., Hoq, Nia, McCormack, Sarah E., Van Pelt, Stacey N., Hanley, Patrick J., Cruz, Conrad Russell Y.
Publicado 2019

Identification of dual positive CD19+/CD3+ T cells in a leukapheresis product undergoing CAR transduction: a case report

por Schultz, Liora, Patel, Shabnum, Davis, Kara Lynn, Ramakrishna, Sneha, Sahaf, Bita, Bhatia, Neehar, Baggott, Christina, Erickson, Courtney, Majzner, Robbie G, Oak, Jean, Bertaina, Alice, Mackall, Crystal, Feldman, Steven
Publicado 2020

HIV-Specific T Cells Can Be Generated against Non-escaped T Cell Epitopes with a GMP-Compliant Manufacturing Platform

por Patel, Shabnum, Hanajiri, Ryo, Grant, Melanie, Saunders, Devin, Van Pelt, Stacey, Keller, Michael, Hanley, Patrick J., Simon, Gary, Nixon, Douglas F., Hardy, David, Jones, R. Brad, Bollard, Catherine M.
Publicado 2019

Mycobacteria-Specific T Cells May Be Expanded From Healthy Donors and Are Near Absent in Primary Immunodeficiency Disorders

por Patel, Shabnum, Lang, Haili, Sani, Gelina, Freeman, Alexandra F., Leiding, Jennifer, Hanley, Patrick J., Cruz, Conrad Russell, Grant, Melanie, Wang, Yunfei, Oshrine, Benjamin, Palmer, Cindy, Holland, Steven M., Bollard, Catherine M., Keller, Michael D.
Publicado 2019

A New Method for Reactivating and Expanding T Cells Specific for Rhizopus oryzae

por Castillo, Paul, Wright, Kaylor E., Kontoyiannis, Dimitrios P., Walsh, Thomas, Patel, Shabnum, Chorvinsky, Elizabeth, Bose, Swaroop, Hazrat, Yasmin, Omer, Bilal, Albert, Nathaniel, Leen, Ann M., Rooney, Cliona M., Bollard, Catherine M., Cruz, Conrad Russell Y.
Publicado 2018

Efficient ex vivo expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates

por Dross, Sandra, Venkataraman, Rasika, Patel, Shabnum, Huang, Meei-Li, Bollard, Catherine M., Rosati, Margherita, Pavlakis, George N., Felber, Barbara K., Bar, Katharine J., Shaw, George M., Jerome, Keith R., Mullins, James I., Kiem, Hans-Peter, Fuller, Deborah Heydenburg, Peterson, Christopher W.
Publicado 2023

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

por Balke-Want, Hyatt, Keerthi, Vimal, Gkitsas, Nikolaos, Mancini, Andrew G., Kurgan, Gavin L., Fowler, Carley, Xu, Peng, Liu, Xikun, Asano, Kyle, Patel, Sunny, Fisher, Christopher J., Brown, Annie K., Tunuguntla, Ramya H., Patel, Shabnum, Sotillo, Elena, Mackall, Crystal L., Feldman, Steven A.
Publicado 2023

S230: CD22 CAR T CELL THERAPY IS SAFE AND EFFECTIVE IN PATIENTS WITH LARGE B CELL LYMPHOMA WHO HAVE RELAPSED AFTER CD19 CAR T CELL THERAPY.

por Frank, Matthew J., Baird, John, Kramer, Anne, Patel, Shabnum, Sahaf, Bita, Craig, Juliana, Crawford, Emma, Younes, Sheren, Oak, Jean, Natkunan, Yasodha, Spiegel, Jay, Ehlinger, Zachary, Chinnasamy, Harshini, Reynolds, Warren, Srinagesh, Hrishi, Su, Yi-Jiun, Egeler, Emily, Feldman, Steven, Mackall, Crystal, Muffly, Lori, Miklos, David
Publicado 2023

A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies

por McCann, Chase D., van Dorp, Christiaan H., Danesh, Ali, Ward, Adam R., Dilling, Thomas R., Mota, Talia M., Zale, Elizabeth, Stevenson, Eva M., Patel, Shabnum, Brumme, Chanson J., Dong, Winnie, Jones, Douglas S., Andresen, Thomas L., Walker, Bruce D., Brumme, Zabrina L., Bollard, Catherine M., Perelson, Alan S., Irvine, Darrell J., Jones, R. Brad
Publicado 2021

Inosine Induces Stemness Features in CAR T cells and Enhances Potency

por Klysz, Dorota D., Fowler, Carley, Malipatlolla, Meena, Stuani, Lucille, Freitas, Katherine A., Meier, Stefanie, Daniel, Bence, Sandor, Katalin, Xu, Peng, Huang, Jing, Labanieh, Louai, Leruste, Amaury, Bashti, Malek, Keerthi, Vimal, Mata-Alcazar, Janette, Gkitsas, Nikolaos, Guerrero, Justin A., Fisher, Chris, Patel, Sunny, Asano, Kyle, Patel, Shabnum, Davis, Kara L., Satpathy, Ansuman T., Feldman, Steven A., Sotillo, Elena, Mackall, Crystal L.
Publicado 2023

EPCT-14. GD2 CAR T-CELLS MEDIATE CLINICAL ACTIVITY AND MANAGEABLE TOXICITY IN CHILDREN AND YOUNG ADULTS WITH H3K27M-MUTATED DIPG AND SPINAL CORD DMG

por Majzner, Robbie, Ramakrishna, Sneha, Mochizuki, Aaron, Patel, Shabnum, Chinnasamy, Harshini, Yeom, Kristen, Schultz, Liora, Richards, Rebecca, Campen, Cynthia, Reschke, Agnes, Mahdi, Jasia, Toland, Angus Martin Shaw, Baggott, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Landrum, Kayla, Erickson, Courtney, Rasmussen, Lindsay, Barsan, Valentin, Tamaresis, John, Marcy, Anne, Kunicki, Michael, Fujimoto, Michelle, Ehlinger, Zach, Kurra, Sreevidya, Cornell, Timothy, Partap, Sonia, Fisher, Paul, Grant, Gerald, Vogel, Hannes, Sahaf, Bita, Davis, Kara, Feldman, Steven, Mackall, Crystal, Monje, Michelle
Publicado 2021

OMIC-11. SINGLE CELL RNA SEQUENCING FROM THE CSF OF SUBJECTS WITH H3K27M+ DIPG/DMG TREATED WITH GD2 CAR T-CELLULAR THERAPY

por Mochizuki, Aaron, Ramakrishna, Sneha, Good, Zina, Patel, Shabnum, Chinnasamy, Harshini, Yeom, Kristen, Schultz, Liora, Richards, Rebecca, Campen, Cynthia, Reschke, Agnes, Mahdi, Jasia, Toland, Angus, Baggot, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Landrum, Kayla, Erickson, Courtney, Rasmussen, Lindsey, Barsan, Valentin, Tamaresis, John, Marcy, Anne, Kunicki, Michael, Celones, Michelle, Ehlinger, Zach, Kurra, Sreevidya, Cornell, Timothy, Partap, Sonia, Fisher, Paul, Grant, Gerald, Vogel, Hannes, Davis, Kara, Feldman, Steven, Sahaf, Bita, Majzner, Robbie, Mackall, Crystal, Monje, Michelle
Publicado 2021

DIPG-15. Major tumor regressions in H3K27M-mutated diffuse midline glioma (DMG) following sequential intravenous (IV) and intracerebroventricular (ICV) delivery of GD2-CAR T-cells

por Monje, Michelle, Majzner, Robbie, Mahdi, Jasia, Ramakrishna, Sneha, Patel, Shabnum, Chinnasamy, Harshini, Yeom, Kristen, Schultz, Liora, Barsan, Valentin, Richards, Rebecca, Campen, Cynthia, Reschke, Agnes, Toland, Angus Martin, Baggott, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Jacobs, Ashley, Yamabe-Kwong, Karen, Rasmussen, Lindsey, Nie, Esther, Green, Sean, Kunicki, Michael, Fujimoto, Michele, Ehlinger, Zach, Reynolds, Warren, Prabhu, Snehit, Warren, Katherine E, Cornell, Tim, Partap, Sonia, Fisher, Paul, Grant, Gerald, Vogel, Hannes, Sahaf, Bita, Davis, Kara, Feldman, Steven, Mackall, Crystal
Publicado 2022

CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial

por Spiegel, Jay Y., Patel, Shabnum, Muffly, Lori, Hossain, Nasheed M., Oak, Jean, Baird, John H., Frank, Matthew J., Shiraz, Parveen, Sahaf, Bita, Craig, Juliana, Iglesias, Maria, Younes, Sheren, Natkunam, Yasodha, Ozawa, Michael G., Yang, Eric, Tamaresis, John, Chinnasamy, Harshini, Ehlinger, Zach, Reynolds, Warren, Lynn, Rachel, Rotiroti, Maria Caterina, Gkitsas, Nikolaos, Arai, Sally, Johnston, Laura, Lowsky, Robert, Majzner, Robbie G., Meyer, Everett, Negrin, Robert S., Rezvani, Andrew R., Sidana, Surbhi, Shizuru, Judith, Weng, Wen-Kai, Mullins, Chelsea, Jacob, Allison, Kirsch, Ilan, Bazzano, Magali, Zhou, Jing, Mackay, Sean, Bornheimer, Scott J., Schultz, Liora, Ramakrishna, Sneha, Davis, Kara L., Kong, Katherine A., Shah, Nirali N., Qin, Haiying, Fry, Terry, Feldman, Steven, Mackall, Crystal L., Miklos, David B.
Publicado 2021

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

por Majzner, Robbie G., Ramakrishna, Sneha, Yeom, Kristen W., Patel, Shabnum, Chinnasamy, Harshini, Schultz, Liora M., Richards, Rebecca M., Jiang, Li, Barsan, Valentin, Mancusi, Rebecca, Geraghty, Anna C., Good, Zinaida, Mochizuki, Aaron Y., Gillespie, Shawn M., Toland, Angus Martin Shaw, Mahdi, Jasia, Reschke, Agnes, Nie, Esther H., Chau, Isabelle J., Rotiroti, Maria Caterina, Mount, Christopher W., Baggott, Christina, Mavroukakis, Sharon, Egeler, Emily, Moon, Jennifer, Erickson, Courtney, Green, Sean, Kunicki, Michael, Fujimoto, Michelle, Ehlinger, Zach, Reynolds, Warren, Kurra, Sreevidya, Warren, Katherine E., Prabhu, Snehit, Vogel, Hannes, Rasmussen, Lindsey, Cornell, Timothy T., Partap, Sonia, Fisher, Paul G., Campen, Cynthia J., Filbin, Mariella G., Grant, Gerald, Sahaf, Bita, Davis, Kara L., Feldman, Steven A., Mackall, Crystal L., Monje, Michelle
Publicado 2022