A dose-finding design for dual-agent trials with patient-specific doses for one agent with application to an opiate detoxification trial

por Mozgunov, Pavel, Cro, Suzie, Lingford-Hughes, Anne, Paterson, Louise M., Jaki, Thomas
Publicado 2022

Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures

por Durant, Claire F., Paterson, Louise M., Turton, Sam, Wilson, Susan J., Myers, James F. M., Muthukumaraswamy, Suresh, Venkataraman, Ashwin, Mick, Inge, Paterson, Susan, Jones, Tessa, Nahar, Limon K., Cordero, Rosa E., Nutt, David J., Lingford-Hughes, Anne
Publicado 2018

Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence

por Vamvakopoulou, Ioanna A., Fonville, Leon, Hayes, Alexandra, McGonigle, John, Elliott, Rebecca, Ersche, Karen D., Flechais, Remy, Orban, Csaba, Murphy, Anna, Smith, Dana G., Suckling, John, Taylor, Eleanor M., Deakin, Bill, Robbins, Trevor W., Nutt, David J., Lingford-Hughes, Anne R., Paterson, Louise M.
Publicado 2022

Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol‐dependent and polysubstance‐dependent individuals

por Nestor, Liam J., Paterson, Louise M., Murphy, Anna, McGonigle, John, Orban, Csaba, Reed, Laurence, Taylor, Eleanor, Flechais, Remy, Smith, Dana, Bullmore, Edward T., Ersche, Karen D., Suckling, John, Elliott, Rebecca, Deakin, Bill, Rabiner, Ilan, Lingford Hughes, Anne, Sahakian, Barbara J., Robbins, Trevor W., Nutt, David J.
Publicado 2018

Disturbances across whole brain networks during reward anticipation in an abstinent addiction population

por Nestor, Liam J., Suckling, John, Ersche, Karen D., Murphy, Anna, McGonigle, John, Orban, Csaba, Paterson, Louise M., Reed, Laurence, Taylor, Eleanor, Flechais, Remy, Smith, Dana, Bullmore, Edward T., Elliott, Rebecca, Deakin, Bill, Rabiner, Ilan, Hughes, Anne-Lingford, Sahakian, Barbara J., Robbins, Trevor W., Nutt, David J.
Publicado 2020

The ICCAM platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part B: fMRI description

por McGonigle, John, Murphy, Anna, Paterson, Louise M, Reed, Laurence J, Nestor, Liam, Nash, Jonathan, Elliott, Rebecca, Ersche, Karen D, Flechais, Remy SA, Newbould, Rexford, Orban, Csaba, Smith, Dana G, Taylor, Eleanor M, Waldman, Adam D, Robbins, Trevor W, Deakin, JF William, Nutt, David J, Lingford-Hughes, Anne R, Suckling, John
Publicado 2016

Naltrexone ameliorates functional network abnormalities in alcohol‐dependent individuals

por Morris, Laurel S., Baek, Kwangyeol, Tait, Roger, Elliott, Rebecca, Ersche, Karen D., Flechais, Remy, McGonigle, John, Murphy, Anna, Nestor, Liam J., Orban, Csaba, Passetti, Filippo, Paterson, Louise M., Rabiner, Ilan, Reed, Laurence, Smith, Dana, Suckling, John, Taylor, Eleanor M., Bullmore, Edward T., Lingford‐Hughes, Anne R., Deakin, Bill, Nutt, David J., Sahakian, Barbara J., Robbins, Trevor W., Voon, Valerie
Publicado 2017

The Use of Baclofen as a Treatment for Alcohol Use Disorder: A Clinical Practice Perspective

por de Beaurepaire, Renaud, Sinclair, Julia M. A., Heydtmann, Mathis, Addolorato, Giovanni, Aubin, Henri-Jean, Beraha, Esther M., Caputo, Fabio, Chick, Jonathan D., de La Selle, Patrick, Franchitto, Nicolas, Garbutt, James C., Haber, Paul S., Jaury, Philippe, Lingford-Hughes, Anne R., Morley, Kirsten C., Müller, Christian A., Owens, Lynn, Pastor, Adam, Paterson, Louise M., Pélissier, Fanny, Rolland, Benjamin, Stafford, Amanda, Thompson, Andrew, van den Brink, Wim, Leggio, Lorenzo, Agabio, Roberta
Publicado 2019

Alterations in white matter microstructure in alcohol and alcohol‐polydrug dependence: Associations with lifetime alcohol and nicotine exposure

por Agunbiade, Kofoworola, Fonville, Leon, McGonigle, John, Elliott, Rebecca, Ersche, Karen D., Flechais, Remy, Orban, Csaba, Murphy, Anna, Smith, Dana G., Suckling, John, Taylor, Eleanor M., Deakin, Bill, Robbins, Trevor W., Nutt, David J., Lingford‐Hughes, Anne R., Paterson, Louise M., Nutt, David, Lingford‐Hughes, Anne, Paterson, Louise, McGonigle, John, Flechais, Remy, Orban, Csaba, Deakin, Bill, Elliott, Rebecca, Murphy, Anna, Taylor, Eleanor, Robbins, Trevor, Ersche, Karen, Suckling, John, Smith, Dana, Reed, Laurence, Passetti, Filippo, Faravelli, Luca, Erritzoe, David, Mick, Inge, Kalk, Nicola, Waldman, Adam, Nestor, Liam, Kuchibatla, Shankar, Boyapati, Venkataramana, Metastasio, Antonio, Faluyi, Yetunde, Fernandez‐Egea, Emilio, Abbott, Sanja, Sahakian, Barbara, Voon, Valerie, Rabiner, Ilan
Publicado 2022