Type 2 Immunity and Its Impact on COVID-19 Infection in the Airways

por Pathinayake, Prabuddha S., Awatade, Nikhil T., Wark, Peter A. B.
Publicado 2023

Innate Immunity and Immune Evasion by Enterovirus 71

por Pathinayake, Prabuddha S., Hsu, Alan C-Y., Wark, Peter A.B.
Publicado 2015

Asthma, COPD and SARS-CoV-2 infection (COVID-19): potential mechanistic insights

por Wark, Peter A.B., Pathinayake, Prabuddha S., Eapen, Mathew Suji, Sohal, Sukhwinder Singh
Publicado 2021

Understanding the Unfolded Protein Response in the Pathogenesis of Asthma

por Pathinayake, Prabuddha S., Hsu, Alan C.-Y., Waters, David W., Hansbro, Philip M., Wood, Lisa G., Wark, Peter A. B.
Publicado 2018

Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5

por Weerawardhana, Asela, Uddin, Md Bashir, Choi, Joo-Hyung, Pathinayake, Prabuddha, Shin, Sung Ho, Chathuranga, Kiramage, Park, Jong-Hyeon, Lee, Jong-Soo
Publicado 2022

Comparison of commercially available differentiation media on cell morphology, function, and anti-viral responses in conditionally reprogrammed human bronchial epithelial cells

por Awatade, Nikhil T., Reid, Andrew T., Nichol, Kristy S., Budden, Kurtis F., Veerati, Punnam Chander, Pathinayake, Prabuddha S., Grainge, Christopher L., Hansbro, Philip M., Wark, Peter A. B.
Publicado 2023

Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study

por Dey, Surajit, Lu, Wenying, Haug, Greg, Chia, Collin, Larby, Josie, Weber, Heinrich C., Gaikwad, Archana Vijay, Bhattarai, Prem, Shahzad, Affan Mahmood, Pathinayake, Prabuddha S., Wark, Peter A. B., Eapen, Mathew Suji, Sohal, Sukhwinder Singh
Publicado 2023

The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders

por Chong, Wai Chin, Shastri, Madhur D, Peterson, Gregory M, Patel, Rahul P, Pathinayake, Prabuddha S, Dua, Kamal, Hansbro, Nicole G, Hsu, Alan C, Wark, Peter A, Shukla, Shakti Dhar, Johansen, Matt D, Schroder, Kate, Hansbro, Philip M
Publicado 2021

A Senescence Bystander Effect in Human Lung Fibroblasts

por Waters, David W., Schuliga, Michael, Pathinayake, Prabuddha S., Wei, Lan, Tan, Hui-Ying, Blokland, Kaj E. C., Jaffar, Jade, Westall, Glen P., Burgess, Janette K., Prêle, Cecilia M., Mutsaers, Steven E., Grainge, Christopher L., Knight, Darryl A.
Publicado 2021

Mucosal Vaccination with Recombinant Lactobacillus casei-Displayed CTA1-Conjugated Consensus Matrix Protein-2 (sM2) Induces Broad Protection against Divergent Influenza Subtypes in...

por Chowdhury, Mohammed Y. E., Li, Rui, Kim, Jae-Hoon, Park, Min-Eun, Kim, Tae-Hwan, Pathinayake, Prabuddha, Weeratunga, Prasanna, Song, Man Ki, Son, Hwa-Young, Hong, Seung-Pyo, Sung, Moon-Hee, Lee, Jong-Soo, Kim, Chul-Joong
Publicado 2014

Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone

por Dey, Surajit, Lu, Wenying, Weber, Heinrich C., Young, Sally, Larby, Josie, Chia, Collin, Haug, Greg, Brake, Samuel James, Myers, Stephen, Gaikwad, Archana Vijay, Bhattarai, Prem, Pathinayake, Prabuddha S., Wark, Peter A. B., Eapen, Mathew Suji, Sohal, Sukhwinder Singh
Publicado 2022

Antiviral immunity is impaired in COPD patients with frequent exacerbations

por Singanayagam, Aran, Loo, Su-Ling, Calderazzo, Maria, Finney, Lydia J., Trujillo Torralbo, Maria-Belen, Bakhsoliani, Eteri, Girkin, Jason, Veerati, Punnam, Pathinayake, Prabuddha S., Nichol, Kristy S., Reid, Andrew, Footitt, Joseph, Wark, Peter A. B., Grainge, Christopher L., Johnston, Sebastian L., Bartlett, Nathan W., Mallia, Patrick
Publicado 2019

Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequen...

por Johansen, Matt D., Mahbub, Rashad M., Idrees, Sobia, Nguyen, Duc H., Miemczyk, Stefan, Pathinayake, Prabuddha, Nichol, Kristy, Hansbro, Nicole G., Gearing, Linden J., Hertzog, Paul J., Gallego-Ortega, David, Britton, Warwick J., Saunders, Bernadette M., Wark, Peter A., Faiz, Alen, Hansbro, Philip M.
Publicado 2022

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi

por Chan, Louisa L. Y., Anderson, Danielle E., Cheng, Hong Sheng, Ivan, Fransiskus Xaverius, Chen, Si, Kang, Adrian E. Z., Foo, Randy, Gamage, Akshamal M., Tiew, Pei Yee, Koh, Mariko Siyue, Lee, Ken Cheah Hooi, Nichol, Kristy, Pathinayake, Prabuddha S., Chan, Yik Lung, Yeo, Tsin Wen, Oliver, Brian G., Wark, Peter A. B., Liu, Linbo, Tan, Nguan Soon, Wang, Lin-Fa, Chotirmall, Sanjay H.
Publicado 2022

Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations

por Singanayagam, Aran, Glanville, Nicholas, Girkin, Jason L., Ching, Yee Man, Marcellini, Andrea, Porter, James D., Toussaint, Marie, Walton, Ross P., Finney, Lydia J., Aniscenko, Julia, Zhu, Jie, Trujillo-Torralbo, Maria-Belen, Calderazzo, Maria Adelaide, Grainge, Chris, Loo, Su-Ling, Veerati, Punnam Chander, Pathinayake, Prabuddha S., Nichol, Kristy S., Reid, Andrew T., James, Phillip L., Solari, Roberto, Wark, Peter A. B., Knight, Darryl A., Moffatt, Miriam F., Cookson, William O., Edwards, Michael R., Mallia, Patrick, Bartlett, Nathan W., Johnston, Sebastian L.
Publicado 2018