Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia

por Jia, Peilin, Wang, Lily, Fanous, Ayman H., Pato, Carlos N., Edwards, Todd L., Zhao, Zhongming
Publicado 2012

Systematic Review and Meta-Analysis on MS-Based Proteomics Applied to Human Peripheral Fluids to Assess Potential Biomarkers of Bipolar Disorder

por Rodrigues, Joao E., Martinho, Ana, Santos, Vítor, Santa, Catia, Madeira, Nuno, Martins, Maria J., Pato, Carlos N., Macedo, Antonio, Manadas, Bruno
Publicado 2022

Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology

por Tung, Victoria Sook Keng, Mathews, Fasil, Boruk, Marina, Suppa, Gabrielle, Foronjy, Robert, Pato, Michele, Pato, Carlos, Knowles, James A., Evgrafov, Oleg V.
Publicado 2023

Cultured Mesenchymal Cells from Nasal Turbinate as a Cellular Model of the Neurodevelopmental Component of Schizophrenia Etiology

por Tung, Victoria Sook Keng, Mathews, Fasil, Boruk, Marina, Suppa, Gabrielle, Foronjy, Robert, Pato, Michele T., Pato, Carlos N., Knowles, James A., Evgrafov, Oleg V.
Publicado 2023

Systematic Review and Meta-Analysis of Mass Spectrometry Proteomics Applied to Human Peripheral Fluids to Assess Potential Biomarkers of Schizophrenia

por Rodrigues, João E., Martinho, Ana, Santa, Catia, Madeira, Nuno, Coroa, Manuel, Santos, Vítor, Martins, Maria J., Pato, Carlos N., Macedo, Antonio, Manadas, Bruno
Publicado 2022

Ancestry-agnostic estimation of DNA sample contamination from sequence reads

por Zhang, Fan, Flickinger, Matthew, Taliun, Sarah A. Gagliano, Abecasis, Gonçalo R., Scott, Laura J., McCaroll, Steven A., Pato, Carlos N., Boehnke, Michael, Kang, Hyun Min
Publicado 2020

Whole-genome analysis of human embryonic stem cells enables rational line selection based on genetic variation

por Merkle, Florian T., Ghosh, Sulagna, Genovese, Giulio, Handsaker, Robert E., Kashin, Seva, Meyer, Daniel, Karczewski, Konrad J., O’Dushlaine, Colm, Pato, Carlos, Pato, Michele, MacArthur, Daniel G., McCarroll, Steven A., Eggan, Kevin
Publicado 2022

Association Study of 167 Candidate Genes for Schizophrenia Selected by a Multi-Domain Evidence-Based Prioritization Algorithm and Neurodevelopmental Hypothesis

por Zhao, Zhongming, Webb, Bradley T., Jia, Peilin, Bigdeli, T. Bernard, Maher, Brion S., van den Oord, Edwin, Bergen, Sarah E., Amdur, Richard L., O'Neill, Francis A., Walsh, Dermot, Thiselton, Dawn L., Chen, Xiangning, Pato, Carlos N., Riley, Brien P., Kendler, Kenneth S., Fanous, Ayman H.
Publicado 2013

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records

por Chen, Chia-Yen, Lee, Phil H., Castro, Victor M., Minnier, Jessica, Charney, Alexander W., Stahl, Eli A., Ruderfer, Douglas M., Murphy, Shawn N., Gainer, Vivian, Cai, Tianxi, Jones, Ian, Pato, Carlos N., Pato, Michele T., Landén, Mikael, Sklar, Pamela, Perlis, Roy H., Smoller, Jordan W.
Publicado 2018

Structural forms of the human amylase locus and their relationships to SNPs, haplotypes, and obesity

por Usher, Christina L, Handsaker, Robert E, Esko, Tõnu, Tuke, Marcus A, Weedon, Michael N, Hastie, Alex R, Cao, Han, Moon, Jennifer E, Kashin, Seva, Fuchsberger, Christian, Metspalu, Andres, Pato, Carlos N, Pato, Michele T, McCarthy, Mark I, Boehnke, Michael, Altshuler, David M, Frayling, Timothy M, Hirschhorn, Joel N, McCarroll, Steven A
Publicado 2015

Recurrent Rare Copy Number Variants Increase Risk for Esotropia

por Whitman, Mary C., Di Gioia, Silvio Alessandro, Chan, Wai-Man, Gelber, Alon, Pratt, Brandon M., Bell, Jessica L., Collins, Thomas E., Knowles, James A., Armoskus, Christopher, Pato, Michele, Pato, Carlos, Shaaban, Sherin, Staffieri, Sandra, MacKinnon, Sarah, Maconachie, Gail D E., Elder, James E., Traboulsi, Elias I., Gottlob, Irene, Mackey, David A., Hunter, David G., Engle, Elizabeth C.
Publicado 2020

The PhenX Toolkit: Get the Most From Your Measures

por Hamilton, Carol M., Strader, Lisa C., Pratt, Joseph G., Maiese, Deborah, Hendershot, Tabitha, Kwok, Richard K., Hammond, Jane A., Huggins, Wayne, Jackman, Dean, Pan, Huaqin, Nettles, Destiney S., Beaty, Terri H., Farrer, Lindsay A., Kraft, Peter, Marazita, Mary L., Ordovas, Jose M., Pato, Carlos N., Spitz, Margaret R., Wagener, Diane, Williams, Michelle, Junkins, Heather A., Harlan, William R., Ramos, Erin M., Haines, Jonathan
Publicado 2011

Complement genes contribute sex-biased vulnerability in diverse illnesses

por Kamitaki, Nolan, Sekar, Aswin, Handsaker, Robert E., de Rivera, Heather, Tooley, Katherine, Morris, David L., Taylor, Kimberly E., Whelan, Christopher W., Tombleson, Philip, Loohuis, Loes M. Olde, Boehnke, Michael, Kimberly, Robert P., Kaufman, Kenneth M., Harley, John B., Langefeld, Carl D., Seidman, Christine E., Pato, Michele T., Pato, Carlos N., Ophoff, Roel A., Graham, Robert R., Criswell, Lindsey A., Vyse, Timothy J., McCarroll, Steven A.
Publicado 2020

CNV analysis in a large schizophrenia sample implicates deletions at 16p12.1 and SLC1A1 and duplications at 1p36.33 and CGNL1

por Rees, Elliott, Walters, James T.R., Chambert, Kimberly D., O'Dushlaine, Colm, Szatkiewicz, Jin, Richards, Alexander L., Georgieva, Lyudmila, Mahoney-Davies, Gerwyn, Legge, Sophie E., Moran, Jennifer L., Genovese, Giulio, Levinson, Douglas, Morris, Derek W., Cormican, Paul, Kendler, Kenneth S., O'Neill, Francis A., Riley, Brien, Gill, Michael, Corvin, Aiden, Sklar, Pamela, Hultman, Christina, Pato, Carlos, Pato, Michele, Sullivan, Patrick F., Gejman, Pablo V., McCarroll, Steven A., O'Donovan, Michael C., Owen, Michael J., Kirov, George
Publicado 2014

Integrating evolutionary and regulatory information with a multispecies approach implicates genes and pathways in obsessive-compulsive disorder

por Noh, Hyun Ji, Tang, Ruqi, Flannick, Jason, O’Dushlaine, Colm, Swofford, Ross, Howrigan, Daniel, Genereux, Diane P., Johnson, Jeremy, van Grootheest, Gerard, Grünblatt, Edna, Andersson, Erik, Djurfeldt, Diana R., Patel, Paresh D., Koltookian, Michele, M. Hultman, Christina, Pato, Michele T., Pato, Carlos N., Rasmussen, Steven A., Jenike, Michael A., Hanna, Gregory L., Stewart, S. Evelyn, Knowles, James A., Ruhrmann, Stephan, Grabe, Hans-Jörgen, Wagner, Michael, Rück, Christian, Mathews, Carol A., Walitza, Susanne, Cath, Daniëlle C., Feng, Guoping, Karlsson, Elinor K., Lindblad-Toh, Kerstin
Publicado 2017

The effect of LRRK2 loss-of-function variants in humans

por Whiffin, Nicola, Armean, Irina M., Kleinman, Aaron, Marshall, Jamie L., Minikel, Eric V., Goodrich, Julia K., Quaife, Nicholas M., Cole, Joanne B., Wang, Qingbo, Karczewski, Konrad J., Cummings, Beryl B., Francioli, Laurent, Laricchia, Kristen, Guan, Anna, Alipanahi, Babak, Morrison, Peter, Baptista, Marco A. S., Merchant, Kalpana M., Ware, James S., Havulinna, Aki S., Iliadou, Bozenna, Lee, Jung-Jin, Nadkarni, Girish N., Whiteman, Cole, Daly, Mark, Esko, Tõnu, Hultman, Christina, Loos, Ruth J. F., Milani, Lili, Palotie, Aarno, Pato, Carlos, Pato, Michele, Saleheen, Danish, Sullivan, Patrick F., Alföldi, Jessica, Cannon, Paul, MacArthur, Daniel G.
Publicado 2020

Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

por Song, J, Bergen, S E, Di Florio, A, Karlsson, R, Charney, A, Ruderfer, D M, Stahl, E A, Chambert, K D, Moran, J L, Gordon-Smith, K, Forty, L, Green, E K, Jones, I, Jones, L, Scolnick, E M, Sklar, P, Smoller, J W, Lichtenstein, P, Hultman, C, Craddock, N, Landén, M, Smoller, Jordan W, Perlis, Roy H, Lee, Phil Hyoun, Castro, Victor M, Hoffnagle, Alison G, Sklar, Pamela, Stahl, Eli A, Purcell, Shaun M, Ruderfer, Douglas M, Charney, Alexander W, Roussos, Panos, Michele Pato, Carlos Pato, Medeiros, Helen, Sobel, Janet, Craddock, Nick, Jones, Ian, Forty, Liz, Florio, Arianna Di, Green, Elaine, Jones, Lisa, Gordon-Smith, Katherine, Landen, Mikael, Hultman, Christina, Jureus, Anders, Bergen, Sarah, McCarroll, Steven, Moran, Jennifer, Smoller, Jordan W, Chambert, Kimberly, Belliveau, Richard A
Publicado 2016

Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations

por Liu, Dongjing, Meyer, Dara, Fennessy, Brian, Feng, Claudia, Cheng, Esther, Johnson, Jessica S., Park, You Jeong, Rieder, Marysia-Kolbe, Ascolillo, Steven, de Pins, Agathe, Dobbyn, Amanda, Lebovitch, Dannielle, Moya, Emily, Nguyen, Tan-Hoang, Wilkins, Lillian, Hassan, Arsalan, Burdick, Katherine E., Buxbaum, Joseph D., Domenici, Enrico, Frangou, Sophia, Hartmann, Annette M., Laurent-Levinson, Claudine, Malhotra, Dheeraj, Pato, Carlos N., Pato, Michele T., Ressler, Kerry, Roussos, Panos, Rujescu, Dan, Arango, Celso, Bertolino, Alessandro, Blasi, Giuseppe, Bocchio-Chiavetto, Luisella, Campion, Dominique, Carr, Vaughan, Fullerton, Janice M., Gennarelli, Massimo, González-Peñas, Javier, Levinson, Douglas F., Mowry, Bryan, Nimgaokar, Vishwajit L., Pergola, Giulio, Rampino, Antonio, Cervilla, Jorge A., Rivera, Margarita, Schwab, Sibylle G., Wildenauer, Dieter B., Daly, Mark, Neale, Benjamin, Singh, Tarjinder, O’Donovan, Michael C., Owen, Michael J., Walters, James T., Ayub, Muhammad, Malhotra, Anil K., Lencz, Todd, Sullivan, Patrick F., Sklar, Pamela, Stahl, Eli A., Huckins, Laura M., Charney, Alexander W.
Publicado 2023

Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry

por Bigdeli, Tim B., Genovese, Giulio, Georgakopoulos, Penelope, Meyers, Jacquelyn L., Peterson, Roseann E., Iyegbe, Conrad O., Medeiros, Helena, Valderrama, Jorge, Achtyes, Eric D., Kotov, Roman, Stahl, Eli A., Abbott, Colony, Azevedo, Maria Helena, Belliveau, Richard A., Bevilacqua, Elizabeth, Bromet, Evelyn J., Byerley, William, Carvalho, Celia Barreto, Chapman, Sinéad B., DeLisi, Lynn E., Dumont, Ashley L., O’Dushlaine, Colm, Evgrafov, Oleg V., Fochtmann, Laura J., Gage, Diane, Kennedy, James L., Kinkead, Becky, Macedo, Antonio, Moran, Jennifer L., Morley, Christopher P., Dewan, Mantosh J., Nemesh, James, Perkins, Diana O., Purcell, Shaun M., Rakofsky, Jeffrey J., Scolnick, Edward M., Sklar, Brooke M., Sklar, Pamela, Smoller, Jordan W., Sullivan, Patrick F., Macciardi, Fabio, Marder, Stephen R., Gur, Ruben C., Gur, Raquel E., Braff, David L., Nicolini, Humberto, Escamilla, Michael A., Vawter, Marquis P., Sobell, Janet L., Malaspina, Dolores, Lehrer, Douglas S., Buckley, Peter F., Rapaport, Mark H., Knowles, James A., Fanous, Ayman H., Pato, Michele T., McCarroll, Steven A., Pato, Carlos N.
Publicado 2019

Self-reported health and smoking status, and body mass index: a case-control comparison based on GEN SCRIP (GENetics of SChizophRenia In Pakistan) data

por Ayub, Muhammad, Arsalan, Arsalan, Khan, Shams-ud-Din Ahmad, Bajwa, Saqib, Hussain, Fahad, Umar, Muhammad, Khizar, Bakht, Sibtain, Muhammad, Butt, Ayesha, Mukhtar-Ul-Haq, Mian, Dogar, Imtiaz Ahmad, Ansari, Moin Ahmad, Shafiq, Sadia, Tariq, Muhammad, Hussain, Mian Iftikhar, Nasar, Amina, Mustafa, Ali Burhan, Taj, Rizwan, Rehman, Raza Ur, Rajput, Atir Hanif, Ambreen, Syeda, Naqvi, Syed Qalb-e-Hyder, Mehmood, Khalid, Khan, Muhammad Younis, Ali, Jawad, Mehmood, Nasir, Amir, Ammara, Nasr, Tanveer, Rabbani, Fazal, Afridi, Adil, Nazar, Zahid, Idrees, Muhammad, Chishti, Ahsan ul Haq, Shamsher Khan, Rana Muzammil, Khan, Anisuzzaman, Aslam, Rubina, Mehdi, Muntazir, Asif, Aftab, Zulqarnain, Ali, Afridi, Jalil, Hussain, Asif, Anwar, Sibtain, Salman, Saad, Khan, Inzemam, Mabood, Zia ul, Hamzalah, Hamzalah, Javed, Adan, Nawaz, Komal, Zahra, Kainat, Nayyar, Urooj, Tooba, Syeda, Rajput, Ammara Ali, Anjum, Anum, Rehman, Ayesha, Kanwal, Maria, Yasmeen, Tahira, Hassan, Sadia, Zaidi, Mariyam Ali, Nayab, Dur E, Kamal, Muhammad, Jamil, Bisma, Malik, Rida, Ul Haq, Ihtisham, Bibi, Zohra, Nawaz, Kalsoom, Anwer, Munaza, Javed, Afzal, Rana, Nusrat Habib, Khan, Muhammad Nasar Sayeed, Naeem, Farooq, Pato, Carlos N, Pato, Michele T, Farooq, Saeed, Knowles, James A
Publicado 2021