Expression of cardiovascular-related microRNAs is altered in L-arginine:glycine amidinotransferase deficient mice

por Jensen, Märit, Müller, Christian, Hübner, Norbert, Patone, Giannino, Saar, Kathrin, Choe, Chi-un, Schwedhelm, Edzard, Zeller, Tanja
Publicado 2022

Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue

por Grunwald, Stefanie Anke, Popp, Oliver, Haafke, Stefanie, Jedraszczak, Nicole, Grieben, Ulrike, Saar, Kathrin, Patone, Giannino, Kress, Wolfram, Steinhagen-Thiessen, Elisabeth, Dittmar, Gunnar, Spuler, Simone
Publicado 2020

Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine

por Rivera, Maria, Fichtner, Iduna, Wulf-Goldenberg, Annika, Sers, Christine, Merk, Johannes, Patone, Giannino, Alp, Keziban M., Kanashova, Tamara, Mertins, Philipp, Hoffmann, Jens, Stein, Ulrike, Walther, Wolfgang
Publicado 2020

A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses

por de Oliveira, Kivia A. P., Kaergel, Eva, Heinig, Matthias, Fontaine, Jean-Fred, Patone, Giannino, Muro, Enrique M., Mathas, Stephan, Hummel, Michael, Andrade-Navarro, Miguel A., Hübner, Norbert, Scheidereit, Claus
Publicado 2016

Dynamic interplay between RPL3- and RPL3L-containing ribosomes modulates mitochondrial activity in the mammalian heart

por Milenkovic, Ivan, Santos Vieira, Helaine Graziele, Lucas, Morghan C, Ruiz-Orera, Jorge, Patone, Giannino, Kesteven, Scott, Wu, Jianxin, Feneley, Michael, Espadas, Guadalupe, Sabidó, Eduard, Hübner, Norbert, van Heesch, Sebastiaan, Völkers, Mirko, Novoa, Eva Maria
Publicado 2023

Natural variation of histone modification and its impact on gene expression in the rat genome

por Rintisch, Carola, Heinig, Matthias, Bauerfeind, Anja, Schafer, Sebastian, Mieth, Christin, Patone, Giannino, Hummel, Oliver, Chen, Wei, Cook, Stuart, Cuppen, Edwin, Colomé-Tatché, Maria, Johannes, Frank, Jansen, Ritsert C., Neil, Helen, Werner, Michel, Pravenec, Michal, Vingron, Martin, Hubner, Norbert
Publicado 2014

A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion

por Witte, Franziska, Ruiz-Orera, Jorge, Mattioli, Camilla Ciolli, Blachut, Susanne, Adami, Eleonora, Schulz, Jana Felicitas, Schneider-Lunitz, Valentin, Hummel, Oliver, Patone, Giannino, Mücke, Michael Benedikt, Šilhavý, Jan, Heinig, Matthias, Bottolo, Leonardo, Sanchis, Daniel, Vingron, Martin, Chekulaeva, Marina, Pravenec, Michal, Hubner, Norbert, van Heesch, Sebastiaan
Publicado 2021

Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant

por Jiang, He, Hooper, Charlotte, Kelly, Matthew, Steeples, Violetta, Simon, Jillian N., Beglov, Julia, Azad, Amar J., Leinhos, Lisa, Bennett, Pauline, Ehler, Elisabeth, Kalisch-Smith, Jacinta I., Sparrow, Duncan B., Fischer, Roman, Heilig, Raphael, Isackson, Henrik, Ehsan, Mehroz, Patone, Giannino, Huebner, Norbert, Davies, Benjamin, Watkins, Hugh, Gehmlich, Katja
Publicado 2021

Impairment of the ER/mitochondria compartment in human cardiomyocytes with PLN p.Arg14del mutation

por Cuello, Friederike, Knaust, Anika E, Saleem, Umber, Loos, Malte, Raabe, Janice, Mosqueira, Diogo, Laufer, Sandra, Schweizer, Michaela, van der Kraak, Petra, Flenner, Frederik, Ulmer, Bärbel M, Braren, Ingke, Yin, Xiaoke, Theofilatos, Konstantinos, Ruiz‐Orera, Jorge, Patone, Giannino, Klampe, Birgit, Schulze, Thomas, Piasecki, Angelika, Pinto, Yigal, Vink, Aryan, Hübner, Norbert, Harding, Sian, Mayr, Manuel, Denning, Chris, Eschenhagen, Thomas, Hansen, Arne
Publicado 2021

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model

por Axelsson Raja, Anna, Wakimoto, Hiroko, DeLaughter, Daniel M., Reichart, Daniel, Gorham, Joshua, Conner, David A., Lun, Mingyue, Probst, Clemens K., Sakai, Norihiko, Knipe, Rachel S., Montesi, Sydney B., Shea, Barry, Adam, Leonard P., Leinwand, Leslie A., Wan, William, Choi, Esther Sue, Lindberg, Eric L., Patone, Giannino, Noseda, Michela, Hübner, Norbert, Seidman, Christine E., Tager, Andrew M., Seidman, J. G., Ho, Carolyn Y.
Publicado 2022

Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins

por Chothani, Sonia, Schäfer, Sebastian, Adami, Eleonora, Viswanathan, Sivakumar, Widjaja, Anissa A., Langley, Sarah R., Tan, Jessie, Wang, Mao, Quaife, Nicholas M., Jian Pua, Chee, D’Agostino, Giuseppe, Guna Shekeran, Shamini, George, Benjamin L., Lim, Stella, Yiqun Cao, Elaine, van Heesch, Sebastiaan, Witte, Franziska, Felkin, Leanne E., Christodoulou, Eleni G., Dong, Jinrui, Blachut, Susanne, Patone, Giannino, Barton, Paul J.R., Hubner, Norbert, Cook, Stuart A., Rackham, Owen J.L.
Publicado 2019

Cells of the adult human heart

por Litviňuková, Monika, Talavera-López, Carlos, Maatz, Henrike, Reichart, Daniel, Worth, Catherine L., Lindberg, Eric L., Kanda, Masatoshi, Polanski, Krzysztof, Heinig, Matthias, Lee, Michael, Nadelmann, Emily R., Roberts, Kenny, Tuck, Liz, Fasouli, Eirini S., DeLaughter, Daniel M., McDonough, Barbara, Wakimoto, Hiroko, Gorham, Joshua M., Samari, Sara, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Patone, Giannino, Boyle, Joseph J., Zhang, Hongbo, Zhang, Hao, Viveiros, Anissa, Oudit, Gavin Y., Bayraktar, Omer Ali, Seidman, J. G., Seidman, Christine E., Noseda, Michela, Hubner, Norbert, Teichmann, Sarah A.
Publicado 2020

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

por Reichart, Daniel, Lindberg, Eric L., Maatz, Henrike, Miranda, Antonio M.A., Viveiros, Anissa, Shvetsov, Nikolay, Gärtner, Anna, Nadelmann, Emily R., Lee, Michael, Kanemaru, Kazumasa, Ruiz-Orera, Jorge, Strohmenger, Viktoria, DeLaughter, Daniel M., Patone, Giannino, Zhang, Hao, Woehler, Andrew, Lippert, Christoph, Kim, Yuri, Adami, Eleonora, Gorham, Joshua M., Barnett, Sam N., Brown, Kemar, Buchan, Rachel J., Chowdhury, Rasheda A., Constantinou, Chrystalla, Cranley, James, Felkin, Leanne E., Fox, Henrik, Ghauri, Ahla, Gummert, Jan, Kanda, Masatoshi, Li, Ruoyan, Mach, Lukas, McDonough, Barbara, Samari, Sara, Shahriaran, Farnoush, Yapp, Clarence, Stanasiuk, Caroline, Theotokis, Pantazis I., Theis, Fabian J., van den Bogaerdt, Antoon, Wakimoto, Hiroko, Ware, James S., Worth, Catherine L., Barton, Paul J.R., Lee, Young-Ae, Teichmann, Sarah A., Milting, Hendrik, Noseda, Michela, Oudit, Gavin Y., Heinig, Matthias, Seidman, Jonathan G., Hubner, Norbert, Seidman, Christine E.
Publicado 2022