The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A

por Patrício, Maria I., Barnard, Alun R., Cox, Christopher I., Blue, Clare, MacLaren, Robert E.
Publicado 2018

Expression of Rab Prenylation Pathway Genes and Relation to Disease Progression in Choroideremia

por Fry, Lewis E., Patrício, Maria I., Jolly, Jasleen K., Xue, Kanmin, MacLaren, Robert E.
Publicado 2021

Self-attenuating adenovirus enables production of recombinant adeno-associated virus for high manufacturing yield without contamination

por Su, Weiheng, Patrício, Maria I., Duffy, Margaret R., Krakowiak, Jakub M., Seymour, Leonard W., Cawood, Ryan
Publicado 2022

Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina

por Patrício, Maria I., Barnard, Alun R., Orlans, Harry O., McClements, Michelle E., MacLaren, Robert E.
Publicado 2017

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

por Salvetti, Anna P., Patrício, Maria I., Barnard, Alun R., Orlans, Harry O., Hickey, Doron G., MacLaren, Robert E.
Publicado 2017

Analysis of Early Cone Dysfunction in an In Vivo Model of Rod-Cone Dystrophy

por Hassall, Mark M., McClements, Michelle E., Barnard, Alun R., Patrício, Maria I., Aslam, Sher A., Maclaren, Robert E.
Publicado 2020

Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy

por Patrício, Maria I., Cox, Christopher I., Blue, Clare, Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E.
Publicado 2019

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues

por Chandler, Laurel C., Barnard, Alun R., Caddy, Sarah L., Patrício, Maria I., McClements, Michelle E., Fu, Howell, Rada, Cristina, MacLaren, Robert E., Xue, Kanmin
Publicado 2019

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues

por Chandler, Laurel C., Barnard, Alun R., Caddy, Sarah L., Patrício, Maria I., McClements, Michelle E., Fu, Howell, Rada, Cristina, MacLaren, Robert E., Xue, Kanmin
Publicado 2023

Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells

por Rodrigues, Carlos F. D., Serrano, Eurico, Patrício, Maria I., Val, Mariana M., Albuquerque, Patrícia, Fonseca, João, Gomes, Célia M. F., Abrunhosa, Antero J., Paiva, Artur, Carvalho, Lina, Botelho, M. Filomena, Almeida, Luís, Carreira, Isabel M., Alpoim, Maria Carmen
Publicado 2018