Gap Junction Intercellular Communication Positively Regulates Cisplatin Toxicity by Inducing DNA Damage through Bystander Signaling

por Arora, Sanjeevani, Heyza, Joshua R., Chalfin, Elaine C., Ruch, Randall J., Patrick, Steve M.
Publicado 2018

Nanoparticle-Mediated Gene Silencing for Sensitization of Lung Cancer to Cisplatin Therapy

por Feldmann, Daniel P., Heyza, Joshua, Zimmermann, Christoph M., Patrick, Steve M., Merkel, Olivia M.
Publicado 2020

Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity

por Kothandapani, Anbarasi, Sawant, Akshada, Dangeti, Venkata Srinivas Mohan Nimai, Sobol, Robert W., Patrick, Steve M.
Publicado 2013

Proteomic Analysis Identifies p62/SQSTM1 as a Critical Player in PARP Inhibitor Resistance

por Uddin, Mohammed Hafiz, Zhou, Jun-Ying, Pimentel, Julio, Patrick, Steve M., Kim, Seongho, Shekhar, Malathy P., Wu, Gen Sheng
Publicado 2022

Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells

por Arora, Sanjeevani, Heyza, Joshua, Zhang, Hao, Kalman-Maltese, Vivian, Tillison, Kristin, Floyd, Ashley M., Chalfin, Elaine M., Bepler, Gerold, Patrick, Steve M.
Publicado 2016

In Vivo Targeting Replication Protein A for Cancer Therapy

por VanderVere-Carozza, Pamela S., Gavande, Navnath S., Jalal, Shadia I., Pollok, Karen E., Ekinci, Elmira, Heyza, Joshua, Patrick, Steve M., Masters, Andi, Turchi, John J., Pawelczak, Katherine S.
Publicado 2022

Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells

por Heyza, Joshua R., Arora, Sanjeevani, Zhang, Hao, Conner, Kayla L., Lei, Wen, Floyd, Ashley M., Deshmukh, Rahul R., Sarver, Jeffrey, Trabbic, Christopher J., Erhardt, Paul, Chan, Tak-Hang, Dou, Q. Ping, Patrick, Steve M.
Publicado 2018

Selective ablation of TRA-1-60(+) pluripotent stem cells suppresses tumor growth of prostate cancer

por White, Jordan M., Ramos, Nicholas, Saliganan, Allen-Dexter, Chung, Joon-Yong, Bell, Meghan, Lindquist, Jacob, Conner, Kayla, Wiesend, Wendy N., Schopperle, Michael, Patrick, Steve M., Kim, Seongho, Heath, Elisabeth I., Escorcia, Freddy E., Viola, Nerissa T.
Publicado 2023

APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response

por Conner, Kayla L, Shaik, Asra N, Marshall, Katie A, Floyd, Ashley M, Ekinci, Elmira, Lindquist, Jacob, Sawant, Akshada, Lei, Wen, Adolph, Madison B, Chelico, Linda, Siriwardena, Sachini U, Bhagwat, Ashok, Kim, Seongho, Cote, Michele L, Patrick, Steve M
Publicado 2020

ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe

por Heyza, Joshua R, Ekinci, Elmira, Lindquist, Jacob, Lei, Wen, Yunker, Christopher, Vinothkumar, Vilvanathan, Rowbotham, Rachelle, Polin, Lisa, Snider, Natalie G, Van Buren, Eric, Watza, Donovan, Back, Jessica B, Chen, Wei, Mamdani, Hirva, Schwartz, Ann G, Turchi, John J, Bepler, Gerold, Patrick, Steve M
Publicado 2023