Dan Tawfik’s Lessons for Protein Engineers about Enzymes Adapting to New Substrates

por Matsumura, Ichiro, Patrick, Wayne M.
Publicado 2022

An enzyme‐centric approach for constructing an amperometric l‐malate biosensor with a long and programmable linear range

por Matthews, Christopher J., Patrick, Wayne M.
Publicado 2023

GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries

por Firth, Andrew E., Patrick, Wayne M.
Publicado 2008

Archaeal Nucleic Acid Ligases and Their Potential in Biotechnology

por Chambers, Cecilia R., Patrick, Wayne M.
Publicado 2015

Quantifying the taxonomic bias in enzymology

por Vickers, Chelsea J., Fraga, Dean, Patrick, Wayne M.
Publicado 2021

Substitutions at the cofactor phosphate-binding site of a clostridial alcohol dehydrogenase lead to unexpected changes in substrate specificity

por Maddock, Danielle J., Patrick, Wayne M., Gerth, Monica L.
Publicado 2015

Structure and kinetics of indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa: Decarboxylation is not essential for indole formation

por Söderholm, Annika, Newton, Matilda S., Patrick, Wayne M., Selmer, Maria
Publicado 2020

New rRNA Gene-Based Phylogenies of the Alphaproteobacteria Provide Perspective on Major Groups, Mitochondrial Ancestry and Phylogenetic Instability

por Ferla, Matteo P., Thrash, J. Cameron, Giovannoni, Stephen J., Patrick, Wayne M.
Publicado 2013

Whither life? Conjectures on the future evolution of biochemistry

por Brewster, Jodi L., Finn, Thomas J., Ramirez, Miguel A., Patrick, Wayne M.
Publicado 2016

Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes

por Soo, Valerie W. C., Yosaatmadja, Yuliana, Squire, Christopher J., Patrick, Wayne M.
Publicado 2016

High-Throughput Chemical Screening Identifies Compounds that Inhibit Different Stages of the Phytophthora agathidicida and Phytophthora cinnamomi Life Cycles

por Lawrence, Scott A., Armstrong, Charlotte B., Patrick, Wayne M., Gerth, Monica L.
Publicado 2017

Assessment of Phenotype Microarray plates for rapid and high-throughput analysis of collateral sensitivity networks

por Dunkley, Elsie J., Chalmers, James D., Cho, Stephanie, Finn, Thomas J., Patrick, Wayne M.
Publicado 2019

Complex Loop Dynamics Underpin Activity, Specificity, and Evolvability in the (βα)(8) Barrel Enzymes of Histidine and Tryptophan Biosynthesis

por Romero-Rivera, Adrian, Corbella, Marina, Parracino, Antonietta, Patrick, Wayne M., Kamerlin, Shina Caroline Lynn
Publicado 2022

Draft Genome Sequence of a Novel Rhizobium Species Isolated from the Marine Macroalga Codium fragile (Oyster Thief)

por Miller, Christopher H., Taylor, Chanel, Owen, Jeremy G., Patrick, Wayne M., Vickers, Chelsea J.
Publicado 2022

Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis

por Brewster, Jodi L., Pachl, Petr, McKellar, James L.O., Selmer, Maria, Squire, Christopher J., Patrick, Wayne M.
Publicado 2021

Complete Genome Sequence of a Novel Pseudomonas fluorescens Strain Isolated from the Flower of Kūmarahou (Pomaderris kumeraho)

por Summers, Monica C., Nowak, Vincent V., Fairhurst, Michael J., Owen, Jeremy G., Gerth, Monica L., Patrick, Wayne M.
Publicado 2021

Uniform binding and negative catalysis at the origin of enzymes

por Noor, Elad, Flamholz, Avi I., Jayaraman, Vijay, Ross, Brian L., Cohen, Yair, Patrick, Wayne M., Gruic‐Sovulj, Ita, Tawfik, Dan S.
Publicado 2022

Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex

por Ramsay, Kay A., Rehman, Attika, Wardell, Samuel T., Martin, Lois W., Bell, Scott C., Patrick, Wayne M., Winstanley, Craig, Lamont, Iain L.
Publicado 2023

The in vitro and in vivo effects of constitutive light expression on a bioluminescent strain of the mouse enteropathogen Citrobacter rodentium

por Read, Hannah M., Mills, Grant, Johnson, Sarah, Tsai, Peter, Dalton, James, Barquist, Lars, Print, Cristin G., Patrick, Wayne M., Wiles, Siouxsie
Publicado 2016

Assessing the effectiveness of oxathiapiprolin toward Phytophthora agathidicida, the causal agent of kauri dieback disease

por Lacey, Randy F, Fairhurst, Michael J, Daley, Kaitlyn J, Ngata-Aerengamate, Te Amohaere, Patterson, Haileigh R, Patrick, Wayne M, Gerth, Monica L
Publicado 2021