Rho Kinase in Eye Disease

por Okumura, Naoki, Nakao, Shintaro, Inoue, Toshihiro, Pattabiraman, Padmanabhan
Publicado 2017

Profiling the miRNA from Exosomes of Non-Pigmented Ciliary Epithelium-Derived Identifies Key Gene Targets Relevant to Primary Open-Angle Glaucoma

por Pattabiraman, Padmanabhan Paranji, Feinstein, Valeria, Beit-Yannai, Elie
Publicado 2023

Cathepsin K Regulates Intraocular Pressure by Modulating Extracellular Matrix Remodeling and Actin-Bundling in the Trabecular Meshwork Outflow Pathway

por Soundararajan, Avinash, Ghag, Sachin Anil, Vuda, Sai Supriya, Wang, Ting, Pattabiraman, Padmanabhan Paranji
Publicado 2021

Novel insight into the role of clusterin on intraocular pressure regulation by modifying actin polymerization and extracellular matrix remodeling in the trabecular meshwork

por Soundararajan, Avinash, Wang, Ting, Ghag, Sachin A., Kang, Min H., Pattabiraman, Padmanabhan P.
Publicado 2022

Multiomics analysis reveals the mechanical stress-dependent changes in trabecular meshwork cytoskeletal-extracellular matrix interactions

por Soundararajan, Avinash, Wang, Ting, Sundararajan, Rekha, Wijeratne, Aruna, Mosley, Amber, Harvey, Faith Christine, Bhattacharya, Sanjoy, Pattabiraman, Padmanabhan Paranji
Publicado 2022

Discovery and Preclinical Development of Netarsudil, a Novel Ocular Hypotensive Agent for the Treatment of Glaucoma

por Lin, Cheng-Wen, Sherman, Bryan, Moore, Lori A., Laethem, Carmen L., Lu, Da-Wen, Pattabiraman, Padmanabhan P., Rao, Ponugoti Vasantha, deLong, Mitchell A., Kopczynski, Casey C.
Publicado 2018

Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms

por McDowell, Colleen M., Kizhatil, Krishnakumar, Elliott, Michael H., Overby, Darryl R., van Batenburg-Sherwood, Joseph, Millar, J. Cameron, Kuehn, Markus H., Zode, Gulab, Acott, Ted S., Anderson, Michael G., Bhattacharya, Sanjoy K., Bertrand, Jacques A., Borras, Terete, Bovenkamp, Diane E., Cheng, Lin, Danias, John, De Ieso, Michael Lucio, Du, Yiqin, Faralli, Jennifer A., Fuchshofer, Rudolf, Ganapathy, Preethi S., Gong, Haiyan, Herberg, Samuel, Hernandez, Humberto, Humphries, Peter, John, Simon W. M., Kaufman, Paul L., Keller, Kate E., Kelley, Mary J., Kelly, Ruth A., Krizaj, David, Kumar, Ajay, Leonard, Brian C., Lieberman, Raquel L., Liton, Paloma, Liu, Yutao, Liu, Katy C., Lopez, Navita N., Mao, Weiming, Mavlyutov, Timur, McDonnell, Fiona, McLellan, Gillian J., Mzyk, Philip, Nartey, Andrews, Pasquale, Louis R., Patel, Gaurang C., Pattabiraman, Padmanabhan P., Peters, Donna M., Raghunathan, Vijaykrishna, Rao, Ponugoti Vasantha, Rayana, Naga, Raychaudhuri, Urmimala, Reina-Torres, Ester, Ren, Ruiyi, Rhee, Douglas, Chowdhury, Uttio Roy, Samples, John R., Samples, E. Griffen, Sharif, Najam, Schuman, Joel S., Sheffield, Val C., Stevenson, Cooper H., Soundararajan, Avinash, Subramanian, Preeti, Sugali, Chenna Kesavulu, Sun, Yang, Toris, Carol B., Torrejon, Karen Y., Vahabikashi, Amir, Vranka, Janice A., Wang, Ting, Willoughby, Colin E., Xin, Chen, Yun, Hongmin, Zhang, Hao F., Fautsch, Michael P., Tamm, Ernst R., Clark, Abbot F., Ethier, C. Ross, Stamer, W. Daniel
Publicado 2022