Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson’s Disease

por Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Fischer, D. Luke, Stoll, Anna C., Sortwell, Caryl E.
Publicado 2018

Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model

por Stoll, Anna C., Kemp, Christopher J., Patterson, Joseph R., Kubik, Michael, Kuhn, Nathan, Benskey, Matthew, Duffy, Megan F., Luk, Kelvin, Sortwell, Caryl E.
Publicado 2023

Dopaminergic Positron Emission Tomography Imaging in the Alpha‐Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease

por Sossi, Vesna, Patterson, Joseph R., McCormick, Siobhan, Kemp, Christopher J., Miller, Kathryn M., Stoll, Anna C., Kuhn, Nathan, Kubik, Michael, Kochmanski, Joseph, Luk, Kelvin C., Sortwell, Caryl E.
Publicado 2022

Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mic...

por Boyd, Sierra L, Kuhn, Nathan C, Patterson, Joseph R, Stoll, Anna C, Zimmerman, Sydney A, Kolanowski, Mason R, Neubecker, Joseph J, Luk, Kelvin C, Ramsson, Eric S, Sortwell, Caryl E, Bernstein, Alison I
Publicado 2023

Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS

por Miller, Kathryn M., Patterson, Joseph R., Kochmanski, Joseph, Kemp, Christopher J., Stoll, Anna C., Onyekpe, Christopher U., Cole-Strauss, Allyson, Steece-Collier, Kathy, Howe, Jacob W., Luk, Kelvin C., Sortwell, Caryl E.
Publicado 2021

Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

por Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Luk, Kelvin C., Tansey, Malú G., Paumier, Katrina L., Kanaan, Nicholas M., Fischer, Luke D., Polinski, Nicole K., Barth, Olivia L., Howe, Jacob W., Vaikath, Nishant N., Majbour, Nour K., El-Agnaf, Omar M. A., Sortwell, Caryl E.
Publicado 2018

Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration

por Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Luk, Kelvin C., Tansey, Malú G., Paumier, Katrina L., Kanaan, Nicholas M., Fischer, D. Luke, Polinski, Nicole K., Barth, Olivia L., Howe, Jacob W., Vaikath, Nishant N., Majbour, Nour K., El-Agnaf, Omar M. A., Sortwell, Caryl E.
Publicado 2018

Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein

por Patterson, Joseph R., Hirst, Warren D., Howe, Jacob W., Russell, Christopher P., Cole-Strauss, Allyson, Kemp, Christopher J., Duffy, Megan F., Lamp, Jared, Umstead, Andrew, Kubik, Michael, Stoll, Anna C., Vega, Irving E., Steece-Collier, Kathy, Chen, Yi, Campbell, Anne C., Nezich, Catherine L., Glajch, Kelly E., Sortwell, Caryl E.
Publicado 2022