CYRI/ Fam49 Proteins Represent a New Class of Rac1 Interactors

por Whitelaw, Jamie A., Lilla, Sergio, Paul, Nikki R., Fort, Loic, Zanivan, Sara, Machesky, Laura M.
Publicado 2019

CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

por Le, Anh Hoang, Yelland, Tamas, Paul, Nikki R., Fort, Loic, Nikolaou, Savvas, Ismail, Shehab, Machesky, Laura M.
Publicado 2021

Specific β-containing Integrins Exert Differential Control on Proliferation and Two-dimensional Collective Cell Migration in Mammary Epithelial Cells

por Jeanes, Alexa I., Wang, Pengbo, Moreno-Layseca, Paulina, Paul, Nikki, Cheung, Julia, Tsang, Ricky, Akhtar, Nasreen, Foster, Fiona M., Brennan, Keith, Streuli, Charles H.
Publicado 2012

An evaluation of multi-excitation-wavelength standing-wave fluorescence microscopy (TartanSW) to improve sampling density in studies of the cell membrane and cytoskeleton

por Schniete, Jana K., Tinning, Peter W., Scrimgeour, Ross C., Robb, Gillian, Kölln, Lisa S., Wesencraft, Katrina, Paul, Nikki R., Bushell, Trevor J., McConnell, Gail
Publicado 2021

NUAK1 governs centrosome replication in pancreatic cancer via MYPT1/PP1β and GSK3β‐dependent regulation of PLK4

por Whyte, Declan, Skalka, George, Walsh, Peter, Wilczynska, Ania, Paul, Nikki R., Mitchell, Claire, Nixon, Colin, Clarke, William, Bushell, Martin, Morton, Jennifer P., Murphy, Daniel J., Muthalagu, Nathiya
Publicado 2023

α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3

por Paul, Nikki R., Allen, Jennifer L., Chapman, Anna, Morlan-Mairal, Maria, Zindy, Egor, Jacquemet, Guillaume, Fernandez del Ama, Laura, Ferizovic, Nermina, Green, David M., Howe, Jonathan D., Ehler, Elisabeth, Hurlstone, Adam, Caswell, Patrick T.
Publicado 2015

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly

por Horton, Edward R., Byron, Adam, Askari, Janet A., Ng, Daniel H. J., Millon-Frémillon, Angélique, Robertson, Joseph, Koper, Ewa J., Paul, Nikki R., Warwood, Stacey, Knight, David, Humphries, Jonathan D., Humphries, Martin J.
Publicado 2015

Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin

por Woodham, Emma F., Paul, Nikki R., Tyrrell, Benjamin, Spence, Heather J., Swaminathan, Karthic, Scribner, Michelle R., Giampazolias, Evangelos, Hedley, Ann, Clark, William, Kage, Frieda, Marston, Daniel J., Hahn, Klaus M., Tait, Stephen W.G., Larue, Lionel, Brakebusch, Cord H., Insall, Robert H., Machesky, Laura M.
Publicado 2017

Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents

por Francis, Stuart, Croft, Daniel, Schüttelkopf, Alexander W., Parry, Charles, Pugliese, Angelo, Cameron, Ken, Claydon, Sophie, Drysdale, Martin, Gardner, Claire, Gohlke, Andrea, Goodwin, Gillian, Gray, Christopher H., Konczal, Jennifer, McDonald, Laura, Mezna, Mokdad, Pannifer, Andrew, Paul, Nikki R., Machesky, Laura, McKinnon, Heather, Bower, Justin
Publicado 2019

Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics

por Koessinger, Anna L., Cloix, Catherine, Koessinger, Dominik, Heiland, Dieter Henrik, Bock, Florian J., Strathdee, Karen, Kinch, Kevin, Martínez-Escardó, Laura, Paul, Nikki R., Nixon, Colin, Malviya, Gaurav, Jackson, Mark R., Campbell, Kirsteen J., Stevenson, Katrina, Davis, Sandeep, Elmasry, Yassmin, Ahmed, Asma, O’Prey, Jim, Ichim, Gabriel, Schnell, Oliver, Stewart, William, Blyth, Karen, Ryan, Kevin M., Chalmers, Anthony J., Norman, Jim C., Tait, Stephen W. G.
Publicado 2022