Mitochondrial Cyclosporine A-Independent Palmitate/Ca(2+)-Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium O...

por Mironova, Galina D., Pavlov, Evgeny V.
Publicado 2021

Tamoxifen-induced knockdown of the mitochondrial calcium uniporter in Thy1-expressing neurons protects mice from hypoxic/ischemic brain injury

por Nichols, Matthew, Pavlov, Evgeny V., Robertson, George S.
Publicado 2018

Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D

por Amodeo, Giuseppe Federico, Krilyuk, Natalya, Pavlov, Evgeny V.
Publicado 2021

Refractive Index Imaging Reveals That Elimination of the ATP Synthase C Subunit Does Not Prevent the Adenine Nucleotide Translocase-Dependent Mitochondrial Permeability Transition

por Neginskaya, Maria A., Morris, Sally E., Pavlov, Evgeny V.
Publicado 2023

From ATP synthase dimers to C-ring conformational changes: unified model of the mitochondrial permeability transition pore

por Amodeo, Giuseppe Federico, Solesio, Maria E., Pavlov, Evgeny V.
Publicado 2017

Polyhydroxybutyrate Targets Mammalian Mitochondria and Increases Permeability of Plasmalemmal and Mitochondrial Membranes

por Elustondo, Pia A., Angelova, Plamena R., Kawalec, Michał, Michalak, Michał, Kurcok, Piotr, Abramov, Andrey Y., Pavlov, Evgeny V.
Publicado 2013

The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function

por Strubbe-Rivera, Jasiel O., Schrad, Jason R., Pavlov, Evgeny V., Conway, James F., Parent, Kristin N., Bazil, Jason N.
Publicado 2021

ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore

por Neginskaya, Maria A., Solesio, Maria E., Berezhnaya, Elena V., Amodeo, Giuseppe F., Mnatsakanyan, Nelli, Jonas, Elizabeth A., Pavlov, Evgeny V.
Publicado 2019

The very low number of calcium-induced permeability transition pores in the single mitochondrion

por Neginskaya, Maria A., Strubbe, Jasiel O., Amodeo, Giuseppe F., West, Benjamin A., Yakar, Shoshana, Bazil, Jason N., Pavlov, Evgeny V.
Publicado 2020

Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity

por Solesio, María E., Peixoto, Pablo M., Debure, Ludovic, Madamba, Stephen M., de Leon, Mony J., Wisniewski, Thomas, Pavlov, Evgeny V., Fossati, Silvia
Publicado 2018

C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition

por Amodeo, Giuseppe Federico, Lee, Brenda Yasie, Krilyuk, Natalya, Filice, Carina Teresa, Valyuk, Denis, Otzen, Daniel Erik, Noskov, Sergey, Leonenko, Zoya, Pavlov, Evgeny V.
Publicado 2021

A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

por Pavlov, Evgeny V., Priault, Muriel, Pietkiewicz, Dawn, Cheng, Emily H.-Y., Antonsson, Bruno, Manon, Stephen, Korsmeyer, Stanley J., Mannella, Carmen A., Kinnally, Kathleen W.
Publicado 2001

Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels

por Stotz, Stephanie C, Scott, Lucas OM, Drummond-Main, Christopher, Avchalumov, Yosef, Girotto, Fernando, Davidsen, Jörn, Gómez-Gárcia, Maria R, Rho, Jong M, Pavlov, Evgeny V, Colicos, Michael A
Publicado 2014

Ca(2+) is a key factor in α-synuclein-induced neurotoxicity

por Angelova, Plamena R., Ludtmann, Marthe H. R., Horrocks, Mathew H., Negoda, Alexander, Cremades, Nunilo, Klenerman, David, Dobson, Christopher M., Wood, Nicholas W., Pavlov, Evgeny V., Gandhi, Sonia, Abramov, Andrey Y.
Publicado 2016

Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F(1) subcomplex

por Mnatsakanyan, Nelli, Park, Han-A, Wu, Jing, He, Xiang, Llaguno, Marc C., Latta, Maria, Miranda, Paige, Murtishi, Besnik, Graham, Morven, Weber, Joachim, Levy, Richard J., Pavlov, Evgeny V., Jonas, Elizabeth A.
Publicado 2022

Tetra-arylborate lipophilic anions as targeting groups

por Gaddale Devanna, Kishore K., Gawel, Justyna M., Prime, Tracy A., Cvetko, Filip, Benincá, Cristiane, Caldwell, Stuart T., Negoda, Alexander, Harrison, Andrew, James, Andrew M., Pavlov, Evgeny V., Murphy, Michael P., Hartley, Richard C.
Publicado 2021

TRPM8 as the rapid testosterone signaling receptor: Implications in the regulation of dimorphic sexual and social behaviors

por Mohandass, Adithya, Krishnan, Vivek, Gribkova, Ekaterina D., Asuthkar, Swapna, Baskaran, Padmamalini, Nersesyan, Yelena, Hussain, Zahir, Wise, Leslie M., George, Robert E., Stokes, Nadarra, Alexander, Brenda M., Cohen, Alejandro M., Pavlov, Evgeny V., Llano, Daniel A., Zhu, Michael X., Thyagarajan, Baskaran, Zakharian, Eleonora
Publicado 2020

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

por Angelova, Plamena R., Choi, Minee L., Berezhnov, Alexey V., Horrocks, Mathew H., Hughes, Craig D., De, Suman, Rodrigues, Margarida, Yapom, Ratsuda, Little, Daniel, Dolt, Karamjit S., Kunath, Tilo, Devine, Michael J., Gissen, Paul, Shchepinov, Mikhail S., Sylantyev, Sergiy, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y., Gandhi, Sonia
Publicado 2020

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

por Ludtmann, Marthe H. R., Angelova, Plamena R., Horrocks, Mathew H., Choi, Minee L., Rodrigues, Margarida, Baev, Artyom Y., Berezhnov, Alexey V., Yao, Zhi, Little, Daniel, Banushi, Blerida, Al-Menhali, Afnan Saleh, Ranasinghe, Rohan T., Whiten, Daniel R., Yapom, Ratsuda, Dolt, Karamjit Singh, Devine, Michael J., Gissen, Paul, Kunath, Tilo, Jaganjac, Morana, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y., Gandhi, Sonia
Publicado 2018