Modeling human disease in rodents by CRISPR/Cas9 genome editing

por Birling, Marie-Christine, Herault, Yann, Pavlovic, Guillaume
Publicado 2017

Introduction to mammalian genome special issue: the microbiome in human health and disease

por Pavlovic, Guillaume, Seong, Je Kyung, Weinstock, George M.
Publicado 2021

Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety

por Teboul, Lydia, Herault, Yann, Wells, Sara, Qasim, Waseem, Pavlovic, Guillaume
Publicado 2020

Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE

por Birling, Marie-Christine, Schaeffer, Laurence, André, Philippe, Lindner, Loic, Maréchal, Damien, Ayadi, Abdel, Sorg, Tania, Pavlovic, Guillaume, Hérault, Yann
Publicado 2017

Increased On-Target Rate and Risk of Concatemerization after CRISPR-Enhanced Targeting in ES Cells

por Erbs, Valérie, Lorentz, Romain, Eisenman, Benjamin, Schaeffer, Laurence, Luppi, Laurence, Lindner, Loic, Hérault, Yann, Pavlovic, Guillaume, Wattenhofer-Donzé, Marie, Birling, Marie-Christine
Publicado 2023

Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy

por Totain, Emmanuelle, Lindner, Loïc, Martin, Nicolas, Misseri, Yolande, Iché, Alexandra, Birling, Marie-Christine, Sorg, Tania, Herault, Yann, Bousquet-Melou, Alain, Bouillé, Pascale, Duthoit, Christine, Pavlovic, Guillaume, Boullier, Severine
Publicado 2023

Distinct fibroblast lineages determine dermal architecture in skin development and repair

por Driskell, Ryan R., Lichtenberger, Beate M., Hoste, Esther, Kretzschmar, Kai, Simons, Ben D., Charalambous, Marika, Ferron, Sacri R., Herault, Yann, Pavlovic, Guillaume, Ferguson-Smith, Anne C., Watt, Fiona M.
Publicado 2013

Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models

por Meziane, Hamid, Birling, Marie-Christine, Wendling, Olivia, Leblanc, Sophie, Dubos, Aline, Selloum, Mohammed, Pavlovic, Guillaume, Sorg, Tania, Kalscheuer, Vera M., Billuart, Pierre, Laumonnier, Frédéric, Chelly, Jamel, van Bokhoven, Hans, Herault, Yann
Publicado 2022

Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome

por Brault, Véronique, Nguyen, Thu Lan, Flores-Gutiérrez, Javier, Iacono, Giovanni, Birling, Marie-Christine, Lalanne, Valérie, Meziane, Hamid, Manousopoulou, Antigoni, Pavlovic, Guillaume, Lindner, Loïc, Selloum, Mohammed, Sorg, Tania, Yu, Eugene, Garbis, Spiros D., Hérault, Yann
Publicado 2021

Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction

por Codner, Gemma F., Lindner, Loic, Caulder, Adam, Wattenhofer-Donzé, Marie, Radage, Adam, Mertz, Annelyse, Eisenmann, Benjamin, Mianné, Joffrey, Evans, Edward P., Beechey, Colin V., Fray, Martin D., Birling, Marie-Christine, Hérault, Yann, Pavlovic, Guillaume, Teboul, Lydia
Publicado 2016

A new mouse model of ARX dup24 recapitulates the patients’ behavioral and fine motor alterations

por Dubos, Aline, Meziane, Hamid, Iacono, Giovanni, Curie, Aurore, Riet, Fabrice, Martin, Christelle, Loaëc, Nadège, Birling, Marie-Christine, Selloum, Mohammed, Normand, Elisabeth, Pavlovic, Guillaume, Sorg, Tania, Stunnenberg, Henk G, Chelly, Jamel, Humeau, Yann, Friocourt, Gaëlle, Hérault, Yann
Publicado 2018

Atp6ap2 ablation in adult mice impairs viability through multiple organ deficiencies

por Wendling, Olivia, Champy, Marie-France, Jaubert, Solène, Pavlovic, Guillaume, Dubos, Aline, Lindner, Loic, Jacobs, Hugues, Mark, Manuel, Combe, Roy, Da Cruz, Isabelle Goncalves, Luche, Hervé, Mudgett, John S., Rosahl, Thomas, Sorg, Tania, Malissen, Marie, Reilly, Patrick T., Hérault, Yann
Publicado 2017

TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis

por Ivanova, Ekaterina L., Gilet, Johan G., Sulimenko, Vadym, Duchon, Arnaud, Rudolf, Gabrielle, Runge, Karen, Collins, Stephan C., Asselin, Laure, Broix, Loic, Drouot, Nathalie, Tilly, Peggy, Nusbaum, Patrick, Vincent, Alexandre, Magnant, William, Skory, Valerie, Birling, Marie-Christine, Pavlovic, Guillaume, Godin, Juliette D., Yalcin, Binnaz, Hérault, Yann, Dráber, Pavel, Chelly, Jamel, Hinckelmann, Maria-Victoria
Publicado 2019

Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome

por Sellier, Chantal, Buijsen, Ronald A.M., He, Fang, Natla, Sam, Jung, Laura, Tropel, Philippe, Gaucherot, Angeline, Jacobs, Hugues, Meziane, Hamid, Vincent, Alexandre, Champy, Marie-France, Sorg, Tania, Pavlovic, Guillaume, Wattenhofer-Donze, Marie, Birling, Marie-Christine, Oulad-Abdelghani, Mustapha, Eberling, Pascal, Ruffenach, Frank, Joint, Mathilde, Anheim, Mathieu, Martinez-Cerdeno, Veronica, Tassone, Flora, Willemsen, Rob, Hukema, Renate K., Viville, Stéphane, Martinat, Cecile, Todd, Peter K., Charlet-Berguerand, Nicolas
Publicado 2017

Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project

por Ayadi, Abdel, Birling, Marie-Christine, Bottomley, Joanna, Bussell, James, Fuchs, Helmut, Fray, Martin, Gailus-Durner, Valérie, Greenaway, Simon, Houghton, Richard, Karp, Natasha, Leblanc, Sophie, Lengger, Christoph, Maier, Holger, Mallon, Ann-Marie, Marschall, Susan, Melvin, David, Morgan, Hugh, Pavlovic, Guillaume, Ryder, Ed, Skarnes, William C., Selloum, Mohammed, Ramirez-Solis, Ramiro, Sorg, Tania, Teboul, Lydia, Vasseur, Laurent, Walling, Alison, Weaver, Tom, Wells, Sara, White, Jacqui K., Bradley, Allan, Adams, David J., Steel, Karen P., Hrabě de Angelis, Martin, Brown, Steve D., Herault, Yann
Publicado 2012

Disease Model Discovery from 3,328 Gene Knockouts by The International Mouse Phenotyping Consortium

por Meehan, Terrence F., Conte, Nathalie, West, David B., Jacobsen, Julius O., Mason, Jeremy, Warren, Jonathan, Chen, Chao-Kung, Tudose, Ilinca, Relac, Mike, Matthews, Peter, Karp, Natasha, Santos, Luis, Fiegel, Tanja, Ring, Natalie, Westerberg, Henrik, Greenaway, Simon, Sneddon, Duncan, Morgan, Hugh, Codner, Gemma F, Stewart, Michelle E, Brown, James, Horner, Neil, Haendel, Melissa, Washington, Nicole, Mungall, Christopher J., Reynolds, Corey L, Gallegos, Juan, Gailus-Durner, Valerie, Sorg, Tania, Pavlovic, Guillaume, Bower, Lynette R, Moore, Mark, Morse, Iva, Gao, Xiang, Tocchini-Valentini, Glauco P, Obata, Yuichi, Cho, Soo Young, Seong, Je Kyung, Seavitt, John, Beaudet, Arthur L., Dickinson, Mary E., Herault, Yann, Wurst, Wolfgang, de Angelis, Martin Hrabe, Lloyd, K.C. Kent, Flenniken, Ann M, Nutter, Lauryl MJ, Newbigging, Susan, McKerlie, Colin, Justice, Monica J., Murray, Stephen A., Svenson, Karen L., Braun, Robert E., White, Jacqueline K., Bradley, Allan, Flicek, Paul, Wells, Sara, Skarnes, William C., Adams, David J., Parkinson, Helen, Mallon, Ann-Marie, Brown, Steve D.M., Smedley, Damian
Publicado 2017

The mammalian gene function resource: the international knockout mouse consortium

por Bradley, Allan, Anastassiadis, Konstantinos, Ayadi, Abdelkader, Battey, James F., Bell, Cindy, Birling, Marie-Christine, Bottomley, Joanna, Brown, Steve D., Bürger, Antje, Bult, Carol J., Bushell, Wendy, Collins, Francis S., Desaintes, Christian, Doe, Brendan, Economides, Aris, Eppig, Janan T., Finnell, Richard H., Fletcher, Colin, Fray, Martin, Frendewey, David, Friedel, Roland H., Grosveld, Frank G., Hansen, Jens, Hérault, Yann, Hicks, Geoffrey, Hörlein, Andreas, Houghton, Richard, Hrabé de Angelis, Martin, Huylebroeck, Danny, Iyer, Vivek, de Jong, Pieter J., Kadin, James A., Kaloff, Cornelia, Kennedy, Karen, Koutsourakis, Manousos, Kent Lloyd, K. C., Marschall, Susan, Mason, Jeremy, McKerlie, Colin, McLeod, Michael P., von Melchner, Harald, Moore, Mark, Mujica, Alejandro O., Nagy, Andras, Nefedov, Mikhail, Nutter, Lauryl M., Pavlovic, Guillaume, Peterson, Jane L., Pollock, Jonathan, Ramirez-Solis, Ramiro, Rancourt, Derrick E., Raspa, Marcello, Remacle, Jacques E., Ringwald, Martin, Rosen, Barry, Rosenthal, Nadia, Rossant, Janet, Ruiz Noppinger, Patricia, Ryder, Ed, Schick, Joel Zupicich, Schnütgen, Frank, Schofield, Paul, Seisenberger, Claudia, Selloum, Mohammed, Simpson, Elizabeth M., Skarnes, William C., Smedley, Damian, Stanford, William L., Francis Stewart, A., Stone, Kevin, Swan, Kate, Tadepally, Hamsa, Teboul, Lydia, Tocchini-Valentini, Glauco P., Valenzuela, David, West, Anthony P., Yamamura, Ken-ichi, Yoshinaga, Yuko, Wurst, Wolfgang
Publicado 2012

Analysis of mammalian gene function through broad based phenotypic screens across a consortium of mouse clinics

por de Angelis, Martin Hrabě, Nicholson, George, Selloum, Mohammed, White, Jacqui, Morgan, Hugh, Ramirez-Solis, Ramiro, Sorg, Tania, Wells, Sara, Fuchs, Helmut, Fray, Martin, Adams, David J, Adams, Niels C, Adler, Thure, Aguilar-Pimentel, Antonio, Ali-Hadji, Dalila, Amann, Gregory, André, Philippe, Atkins, Sarah, Auburtin, Aurelie, Ayadi, Abdel, Becker, Julien, Becker, Lore, Bedu, Elodie, Bekeredjian, Raffi, Birling, Marie-Christine, Blake, Andrew, Bottomley, Joanna, Bowl, Mike, Brault, Véronique, Busch, Dirk H, Bussell, James N, Calzada-Wack, Julia, Cater, Heather, Champy, Marie-France, Charles, Philippe, Chevalier, Claire, Chiani, Francesco, Codner, Gemma F, Combe, Roy, Cox, Roger, Dalloneau, Emilie, Dierich, André, Di Fenza, Armida, Doe, Brendan, Duchon, Arnaud, Eickelberg, Oliver, Esapa, Chris T, El Fertak, Lahcen, Feigel, Tanja, Emelyanova, Irina, Estabel, Jeanne, Favor, Jack, Flenniken, Ann, Gambadoro, Alessia, Garrett, Lilian, Gates, Hilary, Gerdin, Anna-Karin, Gkoutos, George, Greenaway, Simon, Glasl, Lisa, Goetz, Patrice, Da Cruz, Isabelle Goncalves, Götz, Alexander, Graw, Jochen, Guimond, Alain, Hans, Wolfgang, Hicks, Geoff, Hölter, Sabine M, Höfler, Heinz, Hancock, John M, Hoehndorf, Robert, Hough, Tertius, Houghton, Richard, Hurt, Anja, Ivandic, Boris, Jacobs, Hughes, Jacquot, Sylvie, Jones, Nora, Karp, Natasha A, Katus, Hugo A, Kitchen, Sharon, Klein-Rodewald, Tanja, Klingenspor, Martin, Klopstock, Thomas, Lalanne, Valerie, Leblanc, Sophie, Lengger, Christoph, le Marchand, Elise, Ludwig, Tonia, Lux, Aline, McKerlie, Colin, Maier, Holger, Mandel, Jean-Louis, Marschall, Susan, Mark, Manuel, Melvin, David G, Meziane, Hamid, Micklich, Kateryna, Mittelhauser, Christophe, Monassier, Laurent, Moulaert, David, Muller, Stéphanie, Naton, Beatrix, Neff, Frauke, Nolan, Patrick M, Nutter, Lauryl MJ, Ollert, Markus, Pavlovic, Guillaume, Pellegata, Natalia S, Peter, Emilie, Petit-Demoulière, Benoit, Pickard, Amanda, Podrini, Christine, Potter, Paul, Pouilly, Laurent, Puk, Oliver, Richardson, David, Rousseau, Stephane, Quintanilla-Fend, Leticia, Quwailid, Mohamed M, Racz, Ildiko, Rathkolb, Birgit, Riet, Fabrice, Rossant, Janet, Roux, Michel, Rozman, Jan, Ryder, Ed, Salisbury, Jennifer, Santos, Luis, Schäble, Karl-Heinz, Schiller, Evelyn, Schrewe, Anja, Schulz, Holger, Steinkamp, Ralf, Simon, Michelle, Stewart, Michelle, Stöger, Claudia, Stöger, Tobias, Sun, Minxuan, Sunter, David, Teboul, Lydia, Tilly, Isabelle, Tocchini-Valentini, Glauco P, Tost, Monica, Treise, Irina, Vasseur, Laurent, Velot, Emilie, Vogt-Weisenhorn, Daniela, Wagner, Christelle, Walling, Alison, Weber, Bruno, Wendling, Olivia, Westerberg, Henrik, Willershäuser, Monja, Wolf, Eckhard, Wolter, Anne, Wood, Joe, Wurst, Wolfgang, Yildirim, Ali Önder, Zeh, Ramona, Zimmer, Andreas, Zimprich, Annemarie, Holmes, Chris, Steel, Karen P, Herault, Yann, Gailus-Durner, Valérie, Mallon, Ann-Marie, Brown, Steve DM
Publicado 2015