Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (T(H)1)/T(H)17 responses and autoimmunity

por Lee, Sung-Uk, Li, Carey F., Mortales, Christie-Lynn, Pawling, Judy, Dennis, James W., Grigorian, Ani, Demetriou, Michael
Publicado 2019

Plasma membrane domain organization regulates EGFR signaling in tumor cells

por Lajoie, Patrick, Partridge, Emily A., Guay, Ginette, Goetz, Jacky G., Pawling, Judy, Lagana, Annick, Joshi, Bharat, Dennis, James W., Nabi, Ivan R.
Publicado 2007

N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial

por Sy, Michael, Newton, Barbara L., Pawling, Judy, Hayama, Ken L., Cordon, Andres, Yu, Zhaoxia, Kuhle, Jens, Dennis, James W., Brandt, Alexander U., Demetriou, Michael
Publicado 2023

Metabolic Reprogramming by Hexosamine Biosynthetic and Golgi N-Glycan Branching Pathways

por Ryczko, Michael C., Pawling, Judy, Chen, Rui, Abdel Rahman, Anas M., Yau, Kevin, Copeland, Julia K., Zhang, Cunjie, Surendra, Anu, Guttman, David S., Figeys, Daniel, Dennis, James W.
Publicado 2016

Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion

por Joshi, Bharat, Pawling, Judy, Shankar, Jay, Pacholczyk, Karina, Kim, Yohan, Tran, Wynn, Meng, Fanrui, Rahman, Anas M. Abdel, Foster, Leonard J., Leong, Hon S., Dennis, James W., Nabi, Ivan R.
Publicado 2019

N-acetylglucosamine drives myelination by triggering oligodendrocyte precursor cell differentiation

por Sy, Michael, Brandt, Alexander U., Lee, Sung-Uk, Newton, Barbara L., Pawling, Judy, Golzar, Autreen, Rahman, Anas M. A., Yu, Zhaoxia, Cooper, Graham, Scheel, Michael, Paul, Friedemann, Dennis, James W., Demetriou, Michael
Publicado 2020

Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration

por Brandt, Alexander U., Sy, Michael, Bellmann-Strobl, Judith, Newton, Barbara L., Pawling, Judy, Zimmermann, Hanna G., Yu, Zhaoxia, Chien, Claudia, Dörr, Jan, Wuerfel, Jens Th., Dennis, James W., Paul, Friedemann, Demetriou, Michael
Publicado 2021

PTP1B regulates non-mitochondrial oxygen consumption via RNF213 to promote tumour survival during hypoxia

por Banh, Robert S., Iorio, Caterina, Marcotte, Richard, Xu, Yang, Cojocari, Dan, Rahman, Anas Abdel, Pawling, Judy, Zhang, Wei, Sinha, Ankit, Rose, Christopher M., Isasa, Marta, Zhang, Shuang, Wu, Ronald, Virtanen, Carl, Hitomi, Toshiaki, Habu, Toshiyuki, Sidhu, Sachdev S., Koizumi, Akio, Wilkins, Sarah E., Kislinger, Thomas, Gygi, Steven P., Schofield, Christopher J., Dennis, James W., Wouters, Bradly G., Neel, Benjamin G.
Publicado 2016

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

por Aregger, Michael, Lawson, Keith A., Billmann, Maximillian, Costanzo, Michael, Tong, Amy H. Y., Chan, Katherine, Rahman, Mahfuzur, Brown, Kevin R., Ross, Catherine, Usaj, Matej, Nedyalkova, Lucy, Sizova, Olga, Habsid, Andrea, Pawling, Judy, Lin, Zhen-Yuan, Abdouni, Hala, Wong, Cassandra J., Weiss, Alexander, Mero, Patricia, Dennis, James W., Gingras, Anne-Claude, Myers, Chad L., Andrews, Brenda J., Boone, Charles, Moffat, Jason
Publicado 2020