Plasmodium vivax Controlled Human Malaria Infection – Progress and Prospects

por Payne, Ruth O., Griffin, Paul M., McCarthy, James S., Draper, Simon J.
Publicado 2017

Assessment of precision in growth inhibition assay (GIA) using human anti-PfRH5 antibodies

por Miura, Kazutoyo, Diouf, Ababacar, Fay, Michael P., Barrett, Jordan R., Payne, Ruth O., Olotu, Ally I., Minassian, Angela M., Silk, Sarah E., Draper, Simon J., Long, Carole A.
Publicado 2023

Harmonization study between three laboratories for expression of malaria vaccine clinical trial IgG antibody ELISA data in µg/mL

por Labbé, Geneviève M., Miura, Kazutoyo, Silk, Sarah E., Gu, Wenjuan, Moon, James E., Jin, Jing, Payne, Ruth O., Fay, Michael P., Dutta, Sheetij, Long, Carole A., Draper, Simon J.
Publicado 2019

Poor CD4(+) T Cell Immunogenicity Limits Humoral Immunity to P. falciparum Transmission-Blocking Candidate Pfs25 in Humans

por Zaric, Marija, Marini, Arianna, Nielsen, Carolyn M., Gupta, Gaurav, Mekhaiel, David, Pham, Thao P., Elias, Sean C., Taylor, Iona J., de Graaf, Hans, Payne, Ruth O., Li, Yuanyuan, Silk, Sarah E., Williams, Chris, Hill, Adrian V. S., Long, Carole A., Miura, Kazutoyo, Biswas, Sumi
Publicado 2021

Protein/AS01(B) vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors

por Nielsen, Carolyn M., Ogbe, Ane, Pedroza-Pacheco, Isabela, Doeleman, Susanne E., Chen, Yue, Silk, Sarah E., Barrett, Jordan R., Elias, Sean C., Miura, Kazutoyo, Diouf, Ababacar, Bardelli, Martino, Dabbs, Rebecca A., Barfod, Lea, Long, Carole A., Haynes, Barton F., Payne, Ruth O., Minassian, Angela M., Bradley, Todd, Draper, Simon J., Borrow, Persephone
Publicado 2021

Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum

por Milne, Kathryn, Ivens, Alasdair, Reid, Adam J, Lotkowska, Magda E, O'Toole, Aine, Sankaranarayanan, Geetha, Munoz Sandoval, Diana, Nahrendorf, Wiebke, Regnault, Clement, Edwards, Nick J, Silk, Sarah E, Payne, Ruth O, Minassian, Angela M, Venkatraman, Navin, Sanders, Mandy J, Hill, Adrian VS, Barrett, Michael, Berriman, Matthew, Draper, Simon J, Rowe, J Alexandra, Spence, Philip J
Publicado 2021

Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralising vaccine-induced human antibody

por Rawlinson, Thomas. A., Barber, Natalie M., Mohring, Franziska, Cho, Jee Sun, Kosaisavee, Varakorn, Gérard, Samuel F., Alanine, Daniel G. W., Labbé, Geneviève M., Elias, Sean C., Silk, Sarah E., Quinkert, Doris, Jin, Jing, Marshall, Jennifer M., Payne, Ruth O., Minassian, Angela M., Russell, Bruce, Rénia, Laurent, Nosten, François H., Moon, Robert W., Higgins, Matthew K., Draper, Simon J.
Publicado 2019

Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01(B) malaria vaccine

por Nielsen, Carolyn M., Barrett, Jordan R., Davis, Christine, Fallon, Jonathan K., Goh, Cyndi, Michell, Ashlin R., Griffin, Catherine, Kwok, Andrew, Loos, Carolin, Darko, Samuel, Laboune, Farida, Tekman, Mehmet, Diouf, Ababacar, Miura, Kazutoyo, Francica, Joseph R., Ransier, Amy, Long, Carole A., Silk, Sarah E., Payne, Ruth O., Minassian, Angela M., Lauffenburger, Douglas A., Seder, Robert A., Douek, Daniel C., Alter, Galit, Draper, Simon J.
Publicado 2023

Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial

por de Graaf, Hans, Payne, Ruth O., Taylor, Iona, Miura, Kazutoyo, Long, Carol A., Elias, Sean C., Zaric, Marija, Minassian, Angela M., Silk, Sarah E., Li, Lee, Poulton, Ian D., Baker, Megan, Draper, Simon J., Gbesemete, Diane, Brendish, Nathan J., Martins, Filipa, Marini, Arianna, Mekhaiel, David, Edwards, Nick J., Roberts, Rachel, Vekemans, Johan, Moyle, Sarah, Faust, Saul N., Berrie, Eleanor, Lawrie, Alison M., Hill, Fergal, Hill, Adrian V. S., Biswas, Sumi
Publicado 2021

Repeat controlled human malaria infection of healthy UK adults with blood-stage Plasmodium falciparum: Safety and parasite growth dynamics

por Salkeld, Jo, Themistocleous, Yrene, Barrett, Jordan R., Mitton, Celia H., Rawlinson, Thomas A., Payne, Ruth O., Hou, Mimi M., Khozoee, Baktash, Edwards, Nick J., Nielsen, Carolyn M., Sandoval, Diana Muñoz, Bach, Florian A., Nahrendorf, Wiebke, Ramon, Raquel Lopez, Baker, Megan, Ramos-Lopez, Fernando, Folegatti, Pedro M., Quinkert, Doris, Ellis, Katherine J., Poulton, Ian D., Lawrie, Alison M., Cho, Jee-Sun, Nugent, Fay L., Spence, Philip J., Silk, Sarah E., Draper, Simon J., Minassian, Angela M.
Publicado 2022

Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01(B) With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing M...

por Rampling, Tommy, Ewer, Katie J., Bowyer, Georgina, Bliss, Carly M., Edwards, Nick J., Wright, Danny, Payne, Ruth O., Venkatraman, Navin, de Barra, Eoghan, Snudden, Claudia M., Poulton, Ian D., de Graaf, Hans, Sukhtankar, Priya, Roberts, Rachel, Ivinson, Karen, Weltzin, Rich, Rajkumar, Bebi-Yassin, Wille-Reece, Ulrike, Lee, Cynthia K., Ockenhouse, Christian F., Sinden, Robert E., Gerry, Stephen, Lawrie, Alison M., Vekemans, Johan, Morelle, Danielle, Lievens, Marc, Ballou, Ripley W., Cooke, Graham S., Faust, Saul N., Gilbert, Sarah, Hill, Adrian V. S.
Publicado 2016

Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies

por Payne, Ruth O., Silk, Sarah E., Elias, Sean C., Milne, Kathryn H., Rawlinson, Thomas A., Llewellyn, David, Shakri, A. Rushdi, Jin, Jing, Labbé, Geneviève M., Edwards, Nick J., Poulton, Ian D., Roberts, Rachel, Farid, Ryan, Jørgensen, Thomas, Alanine, Daniel G.W., de Cassan, Simone C., Higgins, Matthew K., Otto, Thomas D., McCarthy, James S., de Jongh, Willem A., Nicosia, Alfredo, Moyle, Sarah, Hill, Adrian V.S., Berrie, Eleanor, Chitnis, Chetan E., Lawrie, Alison M., Draper, Simon J.
Publicado 2017

Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells

por Jin, Jing, Tarrant, Richard D., Bolam, Emma J., Angell-Manning, Philip, Soegaard, Max, Pattinson, David J., Dulal, Pawan, Silk, Sarah E., Marshall, Jennifer M., Dabbs, Rebecca A., Nugent, Fay L., Barrett, Jordan R., Hjerrild, Kathryn A., Poulsen, Lars, Jørgensen, Thomas, Brenner, Tanja, Baleanu, Ioana N., Parracho, Helena M., Tahiri-Alaoui, Abdessamad, Whale, Gary, Moyle, Sarah, Payne, Ruth O., Minassian, Angela M., Higgins, Matthew K., Detmers, Frank J., Lawrie, Alison M., Douglas, Alexander D., Smith, Robert, de Jongh, Willem A., Berrie, Eleanor, Ashfield, Rebecca, Draper, Simon J.
Publicado 2018

Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies

por Alanine, Daniel G.W., Quinkert, Doris, Kumarasingha, Rasika, Mehmood, Shahid, Donnellan, Francesca R., Minkah, Nana K., Dadonaite, Bernadeta, Diouf, Ababacar, Galaway, Francis, Silk, Sarah E., Jamwal, Abhishek, Marshall, Jennifer M., Miura, Kazutoyo, Foquet, Lander, Elias, Sean C., Labbé, Geneviève M., Douglas, Alexander D., Jin, Jing, Payne, Ruth O., Illingworth, Joseph J., Pattinson, David J., Pulido, David, Williams, Barnabas G., de Jongh, Willem A., Wright, Gavin J., Kappe, Stefan H.I., Robinson, Carol V., Long, Carole A., Crabb, Brendan S., Gilson, Paul R., Higgins, Matthew K., Draper, Simon J.
Publicado 2019

Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination

por Minassian, Angela M., Silk, Sarah E., Barrett, Jordan R., Nielsen, Carolyn M., Miura, Kazutoyo, Diouf, Ababacar, Loos, Carolin, Fallon, Jonathan K., Michell, Ashlin R., White, Michael T., Edwards, Nick J., Poulton, Ian D., Mitton, Celia H., Payne, Ruth O., Marks, Michael, Maxwell-Scott, Hector, Querol-Rubiera, Antonio, Bisnauthsing, Karen, Batra, Rahul, Ogrina, Tatiana, Brendish, Nathan J., Themistocleous, Yrene, Rawlinson, Thomas A., Ellis, Katherine J., Quinkert, Doris, Baker, Megan, Lopez Ramon, Raquel, Ramos Lopez, Fernando, Barfod, Lea, Folegatti, Pedro M., Silman, Daniel, Datoo, Mehreen, Taylor, Iona J., Jin, Jing, Pulido, David, Douglas, Alexander D., de Jongh, Willem A., Smith, Robert, Berrie, Eleanor, Noe, Amy R., Diggs, Carter L., Soisson, Lorraine A., Ashfield, Rebecca, Faust, Saul N., Goodman, Anna L., Lawrie, Alison M., Nugent, Fay L., Alter, Galit, Long, Carole A., Draper, Simon J.
Publicado 2021