Crosstalk between Metabolite Production and Signaling Activity in Breast Cancer

por Çubuk, Cankut, Loucera, Carlos, Peña-Chilet, María, Dopazo, Joaquin
Publicado 2023

Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models

por Esteban-Medina, Marina, Peña-Chilet, María, Loucera, Carlos, Dopazo, Joaquín
Publicado 2019

Mechanistic Models of Signaling Pathways Reveal the Drug Action Mechanisms behind Gender-Specific Gene Expression for Cancer Treatments

por Çubuk, Cankut, Can, Fatma E., Peña-Chilet, María, Dopazo, Joaquín
Publicado 2020

Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer

por Casimiro-Soriguer, Carlos S., Loucera, Carlos, Peña-Chilet, María, Dopazo, Joaquin
Publicado 2022

Discovering potential interactions between rare diseases and COVID-19 by combining mechanistic models of viral infection with statistical modeling

por López-Sánchez, Macarena, Loucera, Carlos, Peña-Chilet, María, Dopazo, Joaquín
Publicado 2022

Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models

por Payá-Milans, Miriam, Peña-Chilet, María, Loucera, Carlos, Esteban-Medina, Marina, Dopazo, Joaquín
Publicado 2023

Mechanistic models of signaling pathways deconvolute the glioblastoma single-cell functional landscape

por Falco, Matías M, Peña-Chilet, María, Loucera, Carlos, Hidalgo, Marta R, Dopazo, Joaquín
Publicado 2020

Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection

por Loucera, Carlos, Esteban-Medina, Marina, Rian, Kinza, Falco, Matías M., Dopazo, Joaquín, Peña-Chilet, María
Publicado 2020

Using mechanistic models for the clinical interpretation of complex genomic variation

por Peña-Chilet, María, Esteban-Medina, Marina, Falco, Matias M., Rian, Kinza, Hidalgo, Marta R., Loucera, Carlos, Dopazo, Joaquín
Publicado 2019

Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments

por Loucera, Carlos, Carmona, Rosario, Esteban-Medina, Marina, Bostelmann, Gerrit, Muñoyerro-Muñiz, Dolores, Villegas, Román, Peña-Chilet, María, Dopazo, Joaquín
Publicado 2023

A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways

por Garrido-Rodriguez, Martín, Lopez-Lopez, Daniel, Ortuno, Francisco M., Peña-Chilet, María, Muñoz, Eduardo, Calzado, Marco A., Dopazo, Joaquin
Publicado 2021

miRNA Expression Analysis: Cell Lines HCC1500 and HCC1937 as Models for Breast Cancer in Young Women and the miR-23a as a Poor Prognostic Biomarker

por Oltra, Sara S, Peña-Chilet, Maria, Martinez, Maria T, Tormo, Eduardo, Cejalvo, Juan Miguel, Climent, Joan, Eroles, Pilar, Lluch, Ana, Ribas, Gloria
Publicado 2020

Acceleration in the DNA methylation age in breast cancer tumours from very young women

por Oltra, Sara S., Peña-Chilet, Maria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Publicado 2019

Breast Cancer in Very Young Patients in a Spanish Cohort: Age as an Independent Bad Prognostic Indicator

por Martínez, María Teresa, Oltra, Sara S, Peña-Chilet, María, Alonso, Elisa, Hernando, Cristina, Burgues, Octavio, Chirivella, Isabel, Bermejo, Begoña, Lluch, Ana, Ribas, Gloria
Publicado 2019

Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data

por Rian, Kinza, Hidalgo, Marta R., Çubuk, Cankut, Falco, Matias M., Loucera, Carlos, Esteban-Medina, Marina, Alamo-Alvarez, Inmaculada, Peña-Chilet, María, Dopazo, Joaquín
Publicado 2021

rs12512631 on the Group Specific Complement (Vitamin D-Binding Protein GC) Implicated in Melanoma Susceptibility

por Peña-Chilet, Maria, Ibarrola-Villava, Maider, Martin-González, Manuel, Feito, Marta, Gomez-Fernandez, Cristina, Planelles, Dolores, Carretero, Gregorio, Lluch, Ana, Nagore, Eduardo, Ribas, Gloria
Publicado 2013

Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women

por Oltra, Sara S., Peña-Chilet, Maria, Vidal-Tomas, Victoria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Publicado 2018

Mechanistic modeling of the SARS-CoV-2 disease map

por Rian, Kinza, Esteban-Medina, Marina, Hidalgo, Marta R., Çubuk, Cankut, Falco, Matias M., Loucera, Carlos, Gunyel, Devrim, Ostaszewski, Marek, Peña-Chilet, María, Dopazo, Joaquín
Publicado 2021

An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice

por Olivares-González, Lorena, Velasco, Sheyla, Gallego, Idoia, Esteban-Medina, Marina, Puras, Gustavo, Loucera, Carlos, Martínez-Romero, Alicia, Peña-Chilet, María, Pedraz, José Luis, Rodrigo, Regina
Publicado 2022

Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin

por Hernando, Barbara, Ibarrola-Villava, Maider, Fernandez, Lara P., Peña-Chilet, Maria, Llorca-Cardeñosa, Marta, Oltra, Sara S., Alonso, Santos, Boyano, Maria Dolores, Martinez-Cadenas, Conrado, Ribas, Gloria
Publicado 2016