Combining docking with pharmacophore filtering for improved virtual screening

por Peach, Megan L, Nicklaus, Marc C
Publicado 2009

QSAR Modeling of Imbalanced High-Throughput Screening Data in PubChem

por Zakharov, Alexey V., Peach, Megan L., Sitzmann, Markus, Nicklaus, Marc C.
Publicado 2014

A New Approach to Radial Basis Function Approximation and Its Application to QSAR

por Zakharov, Alexey V., Peach, Megan L., Sitzmann, Markus, Nicklaus, Marc C.
Publicado 2014

Experimental and Chemoinformatics Study of Tautomerism in a Database of Commercially Available Screening Samples

por Guasch, Laura, Yapamudiyansel, Waruna, Peach, Megan L., Kelley, James A., Barchi, Joseph J., Nicklaus, Marc C.
Publicado 2016

Synthesis of seco-B-Ring Bryostatin Analogue WN-1 via C–C Bond-Forming Hydrogenation: Critical Contribution of the B-Ring in Determining Bryostatin-like and Phorbol 12-Myristate 13...

por Andrews, Ian P., Ketcham, John M., Blumberg, Peter M., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Krische, Michael J.
Publicado 2014

Synthesis of a des-B-Ring Bryostatin Analogue Leads to an Unexpected Ring Expansion of the Bryolactone Core

por Kraft, Matthew B., Poudel, Yam B., Kedei, Noemi, Lewin, Nancy E., Peach, Megan L., Blumberg, Peter M., Keck, Gary E.
Publicado 2014

Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains

por Pu, Yongmei, Kang, Ji-Hye, Sigano, Dina M., Peach, Megan L., Lewin, Nancy E., Marquez, Victor E., Blumberg, Peter M.
Publicado 2014

SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules

por Patel, Hitesh, Ihlenfeldt, Wolf-Dietrich, Judson, Philip N., Moroz, Yurii S., Pevzner, Yuri, Peach, Megan L., Delannée, Victorien, Tarasova, Nadya I., Nicklaus, Marc C.
Publicado 2020

Tricyclic Guanidine Alkaloids from the Marine Sponge Acanthella cavernosa that Stabilize the Tumor Suppressor PDCD4

por Grkovic, Tanja, Blees, Johanna S., Bayer, Magdalena M., Colburn, Nancy H., Thomas, Cheryl L., Henrich, Curtis J., Peach, Megan L., McMahon, James B., Schmid, Tobias, Gustafson, Kirk R.
Publicado 2014

Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

por Peach, Megan L., Beedie, Shaunna L., Chau, Cindy H., Collins, Matthew K., Markolovic, Suzana, Luo, Weiming, Tweedie, David, Steinebach, Christian, Greig, Nigel H., Gütschow, Michael, Vargesson, Neil, Nicklaus, Marc C., Figg, William D.
Publicado 2020

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

por Byun, Jung S., Park, Samson, Yi, Dae Ik, Shin, Jee-Hye, Hernandez, Sara Gil, Hewitt, Stephen M., Nicklaus, Marc C., Peach, Megan L., Guasch, Laura, Tang, Binwu, Wakefield, Lalage M., Yan, Tingfen, Caban, Ambar, Jones, Alana, Kabbout, Mohamed, Vohra, Nasreen, Nápoles, Anna María, Singhal, Sandeep, Yancey, Ryan, De Siervi, Adriana, Gardner, Kevin
Publicado 2019