Can we vaccinate against Type 1 diabetes?

por Peakman, Mark
Publicado 2012

Antigen-Specific Immunotherapy for Type 1 Diabetes: Maximizing the Potential

por Peakman, Mark, von Herrath, Matthias
Publicado 2010

Peptide Immunotherapy for Type 1 Diabetes—Clinical Advances

por Smith, Emma L., Peakman, Mark
Publicado 2018

In silico and ex vivo approaches indicate immune pressure on capsid and non-capsid regions of coxsackie B viruses in the human system

por Kundu, Rhiannon, Knight, Robin, Dunga, Meenakshi, Peakman, Mark
Publicado 2018

Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it?

por Hull, Caroline M., Peakman, Mark, Tree, Timothy I. M.
Publicado 2017

T cell receptor β-chains display abnormal shortening and repertoire sharing in type 1 diabetes

por Gomez-Tourino, Iria, Kamra, Yogesh, Baptista, Roman, Lorenc, Anna, Peakman, Mark
Publicado 2017

Proinsulin-mediated induction of type 1 diabetes in HLA-DR4-transgenic mice

por Verhagen, Johan, Smith, Emma L., Whettlock, Emily M., Macintyre, Benedict, Peakman, Mark
Publicado 2018

Long-Term Outcome of Individuals Treated With Oral Insulin: Diabetes Prevention Trial–Type 1 (DPT-1) oral insulin trial

por Vehik, Kendra, Cuthbertson, David, Ruhlig, Holly, Schatz, Desmond A., Peakman, Mark, Krischer, Jeffrey P.
Publicado 2011

Evaluating T cell responses prior to the onset of type 1 diabetes

por Arif, Sefina, Yusuf, Norkhairin, Domingo‐Vila, Clara, Liu, Yuk‐Fun, Bingley, Polly J., Peakman, Mark
Publicado 2022

What does it take to be healthy? Investigating immune-deficiency in non-immunodeficient scenarios

por Binda, Elisa, Schulz, Reiner, Showera, Ania, Cope, Andrew, Malim, Michael, Cason, John, Peakman, Mark, Hayday, Adrian
Publicado 2012

Proinsulin peptide promotes autoimmune diabetes in a novel HLA-DR3-DQ2-transgenic murine model of spontaneous disease

por Verhagen, Johan, Yusuf, Norkhairin, Smith, Emma L., Whettlock, Emily M., Naran, Kerina, Arif, Sefina, Peakman, Mark
Publicado 2019

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression

por Tree, Timothy I.M., Lawson, Jennifer, Edwards, Hannah, Skowera, Ania, Arif, Sefina, Roep, Bart O., Peakman, Mark
Publicado 2010

Antibodies in the Diagnosis, Prognosis, and Prediction of Psychotic Disorders

por Pollak, Thomas A, Rogers, Jonathan P, Nagele, Robert G, Peakman, Mark, Stone, James M, David, Anthony S, McGuire, Philip
Publicado 2019

Reduction in CD4 Central Memory T-Cell Subset in Costimulation Modulator Abatacept-Treated Patients With Recent-Onset Type 1 Diabetes Is Associated With Slower C-Peptide Decline

por Orban, Tihamer, Beam, Craig A., Xu, Ping, Moore, Keith, Jiang, Qi, Deng, Jun, Muller, Sarah, Gottlieb, Peter, Spain, Lisa, Peakman, Mark
Publicado 2014

Tryptophan metabolism promotes immune evasion in human pancreatic β cells

por Rachdi, Latif, Zhou, Zhicheng, Berthault, Claire, Lourenço, Chloe, Fouque, Alexis, Domet, Thomas, Armanet, Mathieu, You, Sylvaine, Peakman, Mark, Mallone, Roberto, Scharfmann, Raphael
Publicado 2023

Hydrophobic CDR3 residues promote the development of self-reactive T cells

por Stadinski, Brian D., Shekhar, Karthik, Gómez-Touriño, Iria, Jung, Jonathan, Sasaki, Katsuhiro, Sewell, Andrew K., Peakman, Mark, Chakraborty, Arup K., Huseby, Eric S.
Publicado 2016

Tracking immunodynamics by identification of S-G(2)/M-phase T cells in human peripheral blood()()

por Muñoz-Ruiz, Miguel, Pujol-Autonell, Irma, Rhys, Hefin, Long, Heather M., Greco, Maria, Peakman, Mark, Tree, Tim, Hayday, Adrian C., Di Rosa, Francesca
Publicado 2020

Human β-Cell Killing by Autoreactive Preproinsulin-Specific CD8 T Cells Is Predominantly Granule-Mediated With the Potency Dependent Upon T-Cell Receptor Avidity

por Knight, Robin R., Kronenberg, Deborah, Zhao, Min, Huang, Guo Cai, Eichmann, Martin, Bulek, Anna, Wooldridge, Linda, Cole, David K., Sewell, Andrew K., Peakman, Mark, Skowera, Ania
Publicado 2013

Synchronization of the Normal Human Peripheral Immune System: A Comprehensive Circadian Systems Immunology Analysis

por Beam, Craig A., Wasserfall, Clive, Woodwyk, Alyssa, Akers, McKenzie, Rauch, Heather, Blok, Thomas, Mason, Patrice, Vos, Duncan, Perry, Daniel, Brusko, Todd, Peakman, Mark, Atkinson, Mark
Publicado 2020