MYC degradation via AURKB inhibition: a new brake in the path to T-ALL

por Zhang, Wu, Pear, Warren S.
Publicado 2020

NF-kB inhibitor blocks B cell development at two checkpoints

por Feng, Biao, Cheng, Shuhua, Pear, Warren S, Liou, Hsiou-Chi
Publicado 2004

Tribbles in normal and malignant haematopoiesis

por Stein, Sarah J., Mack, Ethan A., Rome, Kelly S., Pear, Warren S.
Publicado 2015

Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand

por Greene, Maxwell, Lai, Yongjie, Pajcini, Kostandin, Bailis, Will, Pear, Warren S., Lancaster, Eric
Publicado 2016

TooManyPeaks identifies drug-resistant-specific regulatory elements from single-cell leukemic epigenomes

por Schwartz, Gregory W., Zhou, Yeqiao, Petrovic, Jelena, Pear, Warren S., Faryabi, Robert B.
Publicado 2021

Ligand-independent Signaling Functions for the B Lymphocyte Antigen Receptor and Their Role in Positive Selection during B Lymphopoiesis

por Bannish, Gregory, Fuentes-Pananá, Ezequiel M., Cambier, John C., Pear, Warren S., Monroe, John G.
Publicado 2001

The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia

por Choi, Sung Hee, Severson, Eric, Pear, Warren S., Liu, Xiaole S., Aster, Jon C., Blacklow, Stephen C.
Publicado 2017

Notch signaling is an important regulator of type 2 immunity

por Tu, LiLi, Fang, Terry C., Artis, David, Shestova, Olga, Pross, Seth E., Maillard, Ivan, Pear, Warren S.
Publicado 2005

Increased Expression of PcG Protein YY1 Negatively Regulates B Cell Development while Allowing Accumulation of Myeloid Cells and LT-HSC Cells

por Pan, Xuan, Jones, Morgan, Jiang, Jie, Zaprazna, Kristina, Yu, Duonan, Pear, Warren, Maillard, Ivan, Atchison, Michael L.
Publicado 2012

P62(dok), a Negative Regulator of Ras and Mitogen-Activated Protein Kinase (Mapk) Activity, Opposes Leukemogenesis by P210(bcr-abl)

por Di Cristofano, Antonio, Niki, Masaru, Zhao, Mingming, Karnell, Fredrick G., Clarkson, Bayard, Pear, Warren S., Van Aelst, Linda, Pandolfi, Pier Paolo
Publicado 2001

TooManyCells identifies and visualizes relationships of single-cell clades

por Schwartz, Gregory W., Zhou, Yeqiao, Petrovic, Jelena, Fasolino, Maria, Xu, Lanwei, Shaffer, Sydney M., Pear, Warren S., Vahedi, Golnaz, Faryabi, Robert B.
Publicado 2020

The requirement for Notch signaling at the β-selection checkpoint in vivo is absolute and independent of the pre–T cell receptor

por Maillard, Ivan, Tu, LiLi, Sambandam, Arivazhagan, Yashiro-Ohtani, Yumi, Millholland, John, Keeshan, Karen, Shestova, Olga, Xu, Lanwei, Bhandoola, Avinash, Pear, Warren S.
Publicado 2006

Notch Ankyrin Repeat Domain Variation Influences Leukemogenesis and Myc Transactivation

por Aster, Jon C., Bodnar, Nick, Xu, Lanwei, Karnell, Fredrick, Milholland, John M., Maillard, Ivan, Histen, Gavin, Nam, Yunsun, Blacklow, Stephen C., Pear, Warren S.
Publicado 2011

IL-1 signaling modulates STAT activation to antagonize retinoic acid signaling and control Th17–iTreg balance

por Basu, Rajatava, Whitley, Sarah K., Bhaumik, Suniti, Zindl, Carlene L., Schoeb, Trenton R., Benveniste, Etty N., Pear, Warren S., Hatton, Robin D., Weaver, Casey T.
Publicado 2015

Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells

por Allman, David, Karnell, Fredrick G., Punt, Jennifer A., Bakkour, Sonia, Xu, Lanwei, Myung, Peggy, Koretzky, Gary A., Pui, John C., Aster, Jon C., Pear, Warren S.
Publicado 2001

Differential Requirement for LAT and SLP-76 in GPVI versus T Cell Receptor Signaling

por Judd, Barbi A., Myung, Peggy S., Obergfell, Achim, Myers, Erin E., Cheng, Alec M., Watson, Stephen P., Pear, Warren S., Allman, David, Shattil, Sanford J., Koretzky, Gary A.
Publicado 2002

Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1

por Fragoso, Rita, Mao, Tin, Wang, Song, Schaffert, Steven, Gong, Xue, Yue, Sibiao, Luong, Richard, Min, Hyeyoung, Yashiro-Ohtani, Yumi, Davis, Mark, Pear, Warren, Chen, Chang-Zheng
Publicado 2012

Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL

por Stein, Sarah J., Mack, Ethan A., Rome, Kelly S., Pajcini, Kostandin V., Ohtani, Takuya, Xu, Lanwei, Li, Yunlei, Meijerink, Jules P. P., Faryabi, Robert B., Pear, Warren S.
Publicado 2016

The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR(+) CD8(+) effector state, and its deletion improves checkpoint blockade

por McClory, Susan E., Bardhan, Oishi, Rome, Kelly S., Giles, Josephine R., Baxter, Amy E., Xu, Lanwei, Gimotty, Phyllis A., Faryabi, Robert B., John Wherry, E., Pear, Warren S., Jordan, Martha S.
Publicado 2023

The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR(+) CD8(+) effector state and its deletion improves checkpoint blockade

por McClory, Susan E., Bardhan, Oishi, Rome, Kelly S., Giles, Josephine R., Baxter, Amy E., Xu, Lanwei, Gimotty, Phyllis A., Faryabi, Robert B., Wherry, E. John, Pear, Warren S., Jordan, Martha S.
Publicado 2023