Targeting memory T cell metabolism to improve immunity

por Corrado, Mauro, Pearce, Erika L.
Publicado 2022

The importance of methionine metabolism

por Klein Geltink, Ramon I, Pearce, Erika L
Publicado 2019

T cell metabolism drives immunity

por Buck, Michael D., O’Sullivan, David, Pearce, Erika L.
Publicado 2015

Metabolic Dynamics of In Vitro CD8+ T Cell Activation

por Edwards-Hicks, Joy, Mitterer, Michael, Pearce, Erika L., Buescher, Joerg M.
Publicado 2020

MZB1 enables efficient interferon α secretion in stimulated plasmacytoid dendritic cells

por Kapoor, Tanya, Corrado, Mauro, Pearce, Erika L., Pearce, Edward J., Grosschedl, Rudolf
Publicado 2020

Deletion of the mitochondria-shaping protein Opa1 during early thymocyte maturation impacts mature memory T cell metabolism

por Corrado, Mauro, Samardžić, Dijana, Giacomello, Marta, Rana, Nisha, Pearce, Erika L., Scorrano, Luca
Publicado 2021

Fatty Acid Oxidation Is Essential for Egg Production by the Parasitic Flatworm Schistosoma mansoni

por Huang, Stanley Ching-Cheng, Freitas, Tori C., Amiel, Eyal, Everts, Bart, Pearce, Erika L., Lok, James B., Pearce, Edward J.
Publicado 2012

mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity

por Pagán, Antonio J., Lee, Lauren J., Edwards-Hicks, Joy, Moens, Cecilia B., Tobin, David M., Busch-Nentwich, Elisabeth M., Pearce, Erika L., Ramakrishnan, Lalita
Publicado 2022

EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism

por Ramamoorthy, Senthilkumar, Kometani, Kohei, Herman, Josip S., Bayer, Marc, Boller, Sören, Edwards-Hicks, Joy, Ramachandran, Haribaskar, Li, Rui, Klein-Geltink, Ramon, Pearce, Erika L., Grün, Dominic, Grosschedl, Rudolf
Publicado 2020

c-Myc-induced transcription factor AP4 is required for CD8(+) T cell-mediated host protection

por Chou, Chun, Pinto, Amelia K., Curtis, Jonathan D., Persaud, Stephen P., Cella, Marina, Lin, Chih-Chung, Edelson, Brian T., Allen, Paul M., Colonna, Marco, Pearce, Erika L., Diamond, Michael S., Egawa, Takeshi
Publicado 2014

IL-33 expression in response to SARS-CoV-2 correlates with seropositivity in COVID-19 convalescent individuals

por Stanczak, Michal A., Sanin, David E., Apostolova, Petya, Nerz, Gabriele, Lampaki, Dimitrios, Hofmann, Maike, Steinmann, Daniel, Krohn-Grimberghe, Marvin, Thimme, Robert, Mittler, Gerhard, Waller, Cornelius F., Pearce, Edward J., Pearce, Erika L.
Publicado 2021

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4(+) T Cell Pathogenicity and Suppresses Autoimmunity

por Angiari, Stefano, Runtsch, Marah C., Sutton, Caroline E., Palsson-McDermott, Eva M., Kelly, Beth, Rana, Nisha, Kane, Harry, Papadopoulou, Gina, Pearce, Erika L., Mills, Kingston H.G., O'Neill, Luke A.J.
Publicado 2020

Sulfur sequestration promotes multicellularity during nutrient limitation

por Kelly, Beth, Carrizo, Gustavo E., Edwards-Hicks, Joy, Sanin, David E., Stanczak, Michal A., Priesnitz, Chantal, Flachsmann, Lea J., Curtis, Jonathan D., Mittler, Gerhard, Musa, Yaarub, Becker, Thomas, Buescher, Joerg M., Pearce, Erika L.
Publicado 2021

Autophagy is essential for effector CD8 T cell survival and memory formation

por Xu, Xiaojin, Araki, Koichi, Li, Shuzhao, Han, Jin-Hwan, Ye, Lilin, Tan, Wendy G., Konieczny, Bogumila T., Bruinsma, Monique W., Martinez, Jennifer, Pearce, Erika L, Green, Douglas R., Jones, Dean P., Virgin, Herbert W., Ahmed, Rafi
Publicado 2014

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

por Field, Cameron S., Baixauli, Francesc, Kyle, Ryan L., Puleston, Daniel J., Cameron, Alanna M., Sanin, David E., Hippen, Keli L., Loschi, Michael, Thangavelu, Govindarajan, Corrado, Mauro, Edwards-Hicks, Joy, Grzes, Katarzyna M., Pearce, Edward J., Blazar, Bruce R., Pearce, Erika L.
Publicado 2020

Triacylglycerol synthesis enhances macrophage inflammatory function

por Castoldi, Angela, Monteiro, Lauar B., van Teijlingen Bakker, Nikki, Sanin, David E., Rana, Nisha, Corrado, Mauro, Cameron, Alanna M., Hässler, Fabian, Matsushita, Mai, Caputa, George, Klein Geltink, Ramon I., Büscher, Jörg, Edwards-Hicks, Joy, Pearce, Erika L., Pearce, Edward J.
Publicado 2020

Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity

por Almeida, Rafael Ribeiro, Vieira, Raquel de Souza, Castoldi, Angela, Terra, Fernanda Fernandes, Melo, Amanda Campelo L., Canesso, Maria Cecília Campos, Lemos, Luísa, Cipelli, Marcella, Rana, Nisha, Hiyane, Meire Ioshie, Pearce, Erika L., Martins, Flaviano dos Santos, Faria, Ana Maria Caetano de, Câmara, Niels Olsen Saraiva
Publicado 2020

Cell-intrinsic lysosomal lipolysis is essential for macrophage alternative activation

por Huang, Stanley Ching-Cheng, Everts, Bart, Ivanova, Yulia, O'Sullivan, David, Nascimento, Marcia, Smith, Amber M., Beatty, Wandy, Love-Gregory, Latisha, Lam, Wing Y., O'Neill, Christina M., Yan, Cong, Du, Hong, Abumrad, Nada A., Urban, Joseph F., Artyomov, Maxim N., Pearce, Erika L., Pearce, Edward J.
Publicado 2014

Arginase 1 is an innate lymphoid cell-intrinsic metabolic checkpoint controlling type 2 inflammation

por Monticelli, Laurel A, Buck, Michael D, Flamar, Anne-Laure, Saenz, Steven A, Wojno, Elia D Tait, Yudanin, Naomi A, Osborne, Lisa C, Hepworth, Matthew R, Tran, Sara V, Rodewald, Hans-Reimer, Shah, Hardik, Cross, Justin R, Diamond, Joshua M, Cantu, Edward, Christie, Jason D, Pearce, Erika L, Artis, David
Publicado 2016

Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect

por Haring, Eileen, Uhl, Franziska M., Andrieux, Geoffroy, Proietti, Michele, Bulashevska, Alla, Sauer, Barbara, Braun, Lukas M., de Vega Gomez, Enrique, Esser, Philipp R., Martin, Stefan F., Pfeifer, Dietmar, Follo, Marie, Schmitt-Graeff, Annette, Buescher, Joerg, Duyster, Justus, Grimbacher, Bodo, Boerries, Melanie, Pearce, Erika L., Zeiser, Robert, Apostolova, Petya
Publicado 2020