An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer

por Garcia-Murillas, Isaac, Sharpe, Rachel, Pearson, Alex, Campbell, James, Natrajan, Rachael, Ashworth, Alan, Turner, Nicholas C
Publicado 2013

FFPE breast tumour blocks provide reliable sources of both germline and malignant DNA for investigation of genetic determinants of individual tumour responses to treatment

por Wilkins, Anna, Chauhan, Ritika, Rust, Alistair, Pearson, Alex, Daley, Frances, Manodoro, Floriana, Fenwick, Kerry, Bliss, Judith, Yarnold, John, Somaiah, Navita
Publicado 2018

Exceptional Response to AKT Inhibition in Patients With Breast Cancer and Germline PTEN Mutations

por Kingston, Belinda, Bailleux, Caroline, Delaloge, Suzette, Schiavon, Gaia, Scott, Veronique, Lacroix-Triki, Magali, Carr, T. Hedley, Kozarewa, Iwanka, Gevensleben, Heidrun, Kemp, Zoe, Pearson, Alex, Turner, Nicholas, André, Fabrice
Publicado 2019

Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations

por Lopez-Knowles, Elena, Pearson, Alex, Schuster, Gene, Gellert, Pascal, Ribas, Ricardo, Yeo, Belinda, Cutts, Ros, Buus, Richard, Garcia-Murillas, Isaac, Haynes, Ben, Martin, Lesley-Ann, Smith, Ian, Turner, Nick, Dowsett, Mitch
Publicado 2018

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

por Turner, Nicholas, Lambros, Maryou B, Horlings, Hugo M., Pearson, Alex, Sharpe, Rachel, Natrajan, Rachael, Geyer, Felipe C, van Kouwenhove, Marieke, Kreike, Bas, Mackay, Alan, Ashworth, Alan, van de Vijver, Marc J, Reis-Filho, Jorge S
Publicado 2010

Homologous recombination DNA repair deficiency and PARP inhibition activity in primary triple negative breast cancer

por Chopra, Neha, Tovey, Holly, Pearson, Alex, Cutts, Ros, Toms, Christy, Proszek, Paula, Hubank, Michael, Dowsett, Mitch, Dodson, Andrew, Daley, Frances, Kriplani, Divya, Gevensleben, Heidi, Davies, Helen Ruth, Degasperi, Andrea, Roylance, Rebecca, Chan, Stephen, Tutt, Andrew, Skene, Anthony, Evans, Abigail, Bliss, Judith M., Nik-Zainal, Serena, Turner, Nicholas C.
Publicado 2020

Olaparib and Ceralasertib (AZD6738) in Patients with Triple-Negative Advanced Breast Cancer: Results from Cohort E of the plasmaMATCH Trial (CRUK/15/010)

por Ring, Alistair, Kilburn, Lucy S., Pearson, Alex, Moretti, Laura, Afshari-Mehr, Angelica, Wardley, Andrew M., Gurel, Bora, Macpherson, Iain R., Riisnaes, Ruth, Baird, Richard D., Martin, Sue, Roylance, Rebecca, Johnson, Hannah, Ferreira, Ana, Winter, Matthew C., Dunne, Kathryn, Copson, Ellen, Hickish, Tamas, Burcombe, Russell, Randle, Kat, Serra, Violeta, Llop-Guevara, Alba, Bliss, Judith M., Turner, Nicolas C.
Publicado 2023