Targeting chemokine receptors in disease – a case study of CCR4

por Solari, Roberto, Pease, James E.
Publicado 2015

The Role of Interleukin-8 and its Receptors in Inflammatory Lung Disease: Implications for Therapy

por Pease, James E., Sabroe, Ian
Publicado 2012

Challenges and Opportunities in the Clinical Development of STING Agonists for Cancer Immunotherapy

por Motedayen Aval, Leila, Pease, James E., Sharma, Rohini, Pinato, David J.
Publicado 2020

A degradatory fate for CCR4 suggests a primary role in Th2 inflammation

por Anderson, Caroline A., Patel, Pallavi, Viney, Jonathan M., Phillips, Rhian M., Solari, Roberto, Pease, James E.
Publicado 2020

A distinct subset of human NK cells expressing HLA-DR expand in response to IL-2 and can aid immune responses to BCG

por Evans, J Henry, Horowitz, Amir, Mehrabi, Maryam, Wise, Emma L, Pease, James E, Riley, Eleanor M, Davis, Daniel M
Publicado 2011

A Requirement for Neutrophil Glycosaminoglycans in Chemokine:Receptor Interactions Is Revealed by the Streptococcal Protease SpyCEP

por Goldblatt, Jennifer, Lawrenson, Richard Ashley, Muir, Luke, Dattani, Saloni, Hoffland, Ashley, Tsuchiya, Tomoko, Kanegasaki, Shiro, Sriskandan, Shiranee, Pease, James E.
Publicado 2019

CXCR3 antagonist VUF10085 binds to an intrahelical site distinct from that of the broad spectrum antagonist TAK–779

por Nedjai, Belinda, Viney, Jonathan M, Li, Hubert, Hull, Caroline, Anderson, Caroline A, Horie, Tomoki, Horuk, Richard, Vaidehi, Nagarajan, Pease, James E
Publicado 2015

CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration

por Fox, James M., Kausar, Fahima, Day, Amy, Osborne, Michael, Hussain, Khansa, Mueller, Anja, Lin, Jessica, Tsuchiya, Tomoko, Kanegasaki, Shiro, Pease, James E.
Publicado 2018

Evidence for the Existence of a CXCL17 Receptor Distinct from GPR35

por Binti Mohd Amir, Nurul A. S., Mackenzie, Amanda E., Jenkins, Laura, Boustani, Karim, Hillier, Marston C., Tsuchiya, Tomoko, Milligan, Graeme, Pease, James E.
Publicado 2018

CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling

por Giblin, Sean P., Ranawana, Sashini, Hassibi, Shyreen, Birchenough, Holly L., Mincham, Kyle T., Snelgrove, Robert J., Tsuchiya, Tomoko, Kanegasaki, Shiro, Dyer, Douglas, Pease, James E.
Publicado 2023

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

por Blazek, Katrina, Eames, Hayley L., Weiss, Miriam, Byrne, Adam J., Perocheau, Dany, Pease, James E., Doyle, Sean, McCann, Fiona, Williams, Richard O., Udalova, Irina A.
Publicado 2015

Pulmonary Epithelial Cell-Derived Cytokine TGF-β1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function

por Denney, Laura, Byrne, Adam J., Shea, Thomas J., Buckley, James S., Pease, James E., Herledan, Gaelle M.F., Walker, Simone A., Gregory, Lisa G., Lloyd, Clare M.
Publicado 2015

Structure and Function of A41, a Vaccinia Virus Chemokine Binding Protein

por Bahar, Mohammad W, Kenyon, Julia C, Putz, Mike M, Abrescia, Nicola G. A, Pease, James E, Wise, Emma L, Stuart, David I, Smith, Geoffrey L, Grimes, Jonathan M
Publicado 2008

Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3

por Nedjai, Belinda, Li, Hubert, Stroke, Ilana L, Wise, Emma L, Webb, Maria L, Merritt, J Robert, Henderson, Ian, Klon, Anthony E, Cole, Andrew G, Horuk, Richard, Vaidehi, Nagarajan, Pease, James E
Publicado 2012