Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment

por Harrison, Emily B., Azam, Salma H., Pecot, Chad V.
Publicado 2018

An integrated model for predicting KRAS dependency

por Tsai, Yihsuan S., Chareddy, Yogitha S., Price, Brandon A., Parker, Joel S., Pecot, Chad V.
Publicado 2023

Coronin 1C inhibits melanoma metastasis through regulation of MT1-MMP-containing extracellular vesicle secretion

por Tagliatela, Alicia C., Hempstead, Stephanie C., Hibshman, Priya S., Hockenberry, Max A., Brighton, Hailey E., Pecot, Chad V., Bear, James E.
Publicado 2020

Consolidation With Pembrolizumab and Nab-Paclitaxel After Induction Platinum-Based Chemotherapy for Advanced Non-Small Cell Lung Cancer

por Patel, Shetal A., Gerber, David E., Deal, Allison, Douglas, Kathe, Pecot, Chad V., Lee, Carrie, Schiller, Joan, Dhruva, Nirav, Weiss, Jared
Publicado 2021

Targeting disialoganglioside GD2 with chimeric antigen receptor-redirected T cells in lung cancer

por Reppel, Loïc, Tsahouridis, Ourania, Akulian, Jason, Davis, Ian J, Lee, Hong, Fucà, Giovanni, Weiss, Jared, Dotti, Gianpietro, Pecot, Chad V, Savoldo, Barbara
Publicado 2022

Rapid idiosyncratic mechanisms of clinical resistance to KRAS G12C inhibition

por Tsai, Yihsuan S., Woodcock, Mark G., Azam, Salma H., Thorne, Leigh B., Kanchi, Krishna L., Parker, Joel S., Vincent, Benjamin G., Pecot, Chad V.
Publicado 2022

High-capacity poly(2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of lung adenocarcinoma

por Vinod, Natasha, Hwang, Duhyeong, Azam, Salma H., Van Swearingen, Amanda E. D., Wayne, Elizabeth, Fussell, Sloane Christian, Sokolsky-Papkov, Marina, Pecot, Chad V., Kabanov, Alexander V.
Publicado 2020

Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration

por Li, Hongxia, Harrison, Emily B., Li, Huizhong, Hirabayashi, Koichi, Chen, Jing, Li, Qi-Xiang, Gunn, Jared, Weiss, Jared, Savoldo, Barbara, Parker, Joel S., Pecot, Chad V., Dotti, Gianpietro, Du, Hongwei
Publicado 2022

Histone deacetylase 11 inhibition promotes breast cancer metastasis from lymph nodes

por Leslie, Patrick L., Chao, Yvonne L., Tsai, Yi-Hsuan, Ghosh, Subrata K., Porrello, Alessandro, Van Swearingen, Amanda E. D., Harrison, Emily B., Cooley, Brian C., Parker, Joel S., Carey, Lisa A., Pecot, Chad V.
Publicado 2019

Suppression of Myeloid Cell Arginase Activity leads to Therapeutic Response in a NSCLC Mouse Model by Activating Anti-Tumor Immunity

por Miret, Juan J., Kirschmeier, Paul, Koyama, Shohei, Zhu, Mingrui, Li, Yvonne Y., Naito, Yujiro, Wu, Min, Malladi, Venkat S., Huang, Wei, Walker, William, Palakurthi, Sangeetha, Dranoff, Glenn, Hammerman, Peter S., Pecot, Chad V., Wong, Kwok-Kin, Akbay, Esra A.
Publicado 2019

A genome‐scale screen reveals context‐dependent ovarian cancer sensitivity to miRNA overexpression

por Shields, Benjamin B, Pecot, Chad V, Gao, Hua, McMillan, Elizabeth, Potts, Malia, Nagel, Christa, Purinton, Scott, Wang, Ying, Ivan, Cristina, Kim, Hyun Seok, Borkowski, Robert J, Khan, Shaheen, Rodriguez‐Aguayo, Cristian, Lopez‐Berestein, Gabriel, Lea, Jayanthi, Gazdar, Adi, Baggerly, Keith A, Sood, Anil K, White, Michael A
Publicado 2015

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

por van den Beucken, Twan, Koch, Elizabeth, Chu, Kenneth, Rupaimoole, Rajesha, Prickaerts, Peggy, Adriaens, Michiel, Voncken, Jan Willem, Harris, Adrian L., Buffa, Francesca M., Haider, Syed, Starmans, Maud H.W., Yao, Cindy Q., Ivan, Mircea, Ivan, Cristina, Pecot, Chad V., Boutros, Paul C., Sood, Anil K., Koritzinsky, Marianne, Wouters, Bradly G.
Publicado 2014

Hypoxia-upregulated microRNA-630 targets Dicer, leading to increased tumor progression

por Rupaimoole, Rajesha, Ivan, Cristina, Yang, Da, Gharpure, Kshipra M., Wu, Sherry Y., Pecot, Chad V., Previs, Rebecca A., Nagaraja, Archana S., Armaiz-Pena, Guillermo N, McGuire, Michael, Pradeep, Sunila, Mangala, Lingegowda S., Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Zhang, Wei, Lopez-Berestein, Gabriel, Calin, George A., Sood, Anil K.
Publicado 2016

Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer

por Murphy, Ryan M., Tasoulas, Jason, Porrello, Alessandro, Carper, Miranda B., Tsai, Yi-Hsuan, Coffey, Alisha R., Kumar, Sunil, Zeng, Peter YF., Schrank, Travis P., Midkiff, Bentley R., Cohen, Stephanie, Salazar, Ashley H., Hayward, Michele C., Hayes, D. Neil, Olshan, Andrew, Gupta, Gaorav P., Nichols, Anthony C., Yarbrough, Wendell G., Pecot, Chad V., Amelio, Antonio L.
Publicado 2022

Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking

por Porrello, Alessandro, Leslie, Patrick L., Harrison, Emily B., Gorentla, Balachandra K., Kattula, Sravya, Ghosh, Subrata K., Azam, Salma H., Holtzhausen, Alisha, Chao, Yvonne L., Hayward, Michele C., Waugh, Trent A., Bae, Sanggyu, Godfrey, Virginia, Randell, Scott H., Oderup, Cecilia, Makowski, Liza, Weiss, Jared, Wilkerson, Matthew D., Hayes, D. Neil, Earp, H. Shelton, Baldwin, Albert S., Wolberg, Alisa S., Pecot, Chad V.
Publicado 2018

A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women

por Bensen, Jeannette T., Graff, Mariaelisa, Young, Kristin L., Sethupathy, Praveen, Parker, Joel, Pecot, Chad V., Currin, Kevin, Haddad, Stephen A., Ruiz-Narváez, Edward A., Haiman, Christopher A., Hong, Chi-Chen, Sucheston-Campbell, Lara E., Zhu, Qianqian, Liu, Song, Yao, Song, Bandera, Elisa V., Rosenberg, Lynn, Lunetta, Kathryn L., Ambrosone, Christine B., Palmer, Julie R., Troester, Melissa A., Olshan, Andrew F.
Publicado 2018

miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

por Pan, Yinghong, Robertson, Gordon, Pedersen, Lykke, Lim, Emilia, Hernandez-Herrera, Anadulce, Rowat, Amy C., Patil, Sagar L., Chan, Clara K., Wen, Yunfei, Zhang, Xinna, Basu-Roy, Upal, Mansukhani, Alka, Chu, Andy, Sipahimalani, Payal, Bowlby, Reanne, Brooks, Denise, Thiessen, Nina, Coarfa, Cristian, Ma, Yussanne, Moore, Richard A., Schein, Jacquie E., Mungall, Andrew J., Liu, Jinsong, Pecot, Chad V., Sood, Anil K., Jones, Steven J.M., Marra, Marco A., Gunaratne, Preethi H.
Publicado 2016

Correction: miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

por Pan, Yinghong, Robertson, Gordon, Pedersen, Lykke, Lim, Emilia, Hernandez-Herrera, Anadulce, Rowat, Amy C., Patil, Sagar L., Chan, Clara K., Wen, Yunfei, Zhang, Xinna, Basu-Roy, Upal, Mansukhani, Alka, Chu, Andy, Sipahimalani, Payal, Bowlby, Reanne, Brooks, Denise, Thiessen, Nina, Coarfa, Cristian, Ma, Yussanne, Moore, Richard A., Schein, Jacquie E., Mungall, Andrew J., Liu, Jinsong, Pecot, Chad V., Sood, Anil K., Jones, Steven J.M., Marra, Marco A., Gunaratne, Preethi H.
Publicado 2017

Hypoxia Mediated Downregulation of miRNA Biogenesis Promotes Tumor Progression

por Rupaimoole, Rajesha, Wu, Sherry Y., Pradeep, Sunila, Ivan, Cristina, Pecot, Chad V., Gharpure, Kshipra M., Nagaraja, Archana S., Armaiz-Pena, Guillermo N., McGuire, Michael, Zand, Behrouz, Dalton, Heather J., Filant, Justyna, Miller, Justin Bottsford, Lu, Chunhua, Sadaoui, Nouara C., Mangala, Lingegowda S., Taylor, Morgan, van den Beucken, Twan, Koch, Elizabeth, Rodriguez-Aguayo, Cristian, Huang, Li, Bar-Eli, Menashe, Wouters, Bradly G., Radovich, Milan, Ivan, Mircea, Calin, George A, Zhang, Wei, Lopez-Berestein, Gabriel, Sood, Anil K.
Publicado 2014

A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer

por Wu, Sherry Y., Rupaimoole, Rajesha, Shen, Fangrong, Pradeep, Sunila, Pecot, Chad V., Ivan, Cristina, Nagaraja, Archana S., Gharpure, Kshipra M., Pham, Elizabeth, Hatakeyama, Hiroto, McGuire, Michael H., Haemmerle, Monika, Vidal-Anaya, Viviana, Olsen, Courtney, Rodriguez-Aguayo, Cristian, Filant, Justyna, Ehsanipour, Ehsan A., Herbrich, Shelley M., Maiti, Sourindra N., Huang, Li, Kim, Ji Hoon, Zhang, Xinna, Han, Hee-Dong, Armaiz-Pena, Guillermo N., Seviour, Elena G., Tucker, Sue, Zhang, Min, Yang, Da, Cooper, Laurence J. N., Ali-Fehmi, Rouba, Bar-Eli, Menashe, Lee, Ju-Seog, Ram, Prahlad T., Baggerly, Keith A., Lopez-Berestein, Gabriel, Hung, Mien-Chie, Sood, Anil K.
Publicado 2016