The ubiquitin ligase HERC1 regulates cell migration via RAF-dependent regulation of MKK3/p38 signaling

por Pedrazza, Leonardo, Schneider, Taiane, Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Publicado 2020

HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases

por García-Cano, Jesús, Martinez-Martinez, Arturo, Sala-Gaston, Joan, Pedrazza, Leonardo, Rosa, Jose Luis
Publicado 2019

Regulation of MAPK Signaling Pathways by the Large HERC Ubiquitin Ligases

por Sala-Gaston, Joan, Costa-Sastre, Laura, Pedrazza, Leonardo, Martinez-Martinez, Arturo, Ventura, Francesc, Rosa, Jose Luis
Publicado 2023

Mesenchymal stem cells decrease lung inflammation during sepsis, acting through inhibition of the MAPK pathway

por Pedrazza, Leonardo, Cubillos-Rojas, Monica, de Mesquita, Fernanda Cristina, Luft, Carolina, Cunha, Aline Andrea, Rosa, Jose Luis, de Oliveira, Jarbas Rodrigues
Publicado 2017

HERC Ubiquitin Ligases in Cancer

por Sala-Gaston, Joan, Martinez-Martinez, Arturo, Pedrazza, Leonardo, Lorenzo-Martín, L. Francisco, Caloto, Rubén, Bustelo, Xosé R., Ventura, Francesc, Rosa, Jose Luis
Publicado 2020

The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses

por Montes-Fernández, Mª Angeles, Pérez-Villegas, Eva Mª, Garcia-Gonzalo, Francesc R., Pedrazza, Leonardo, Rosa, Jose Luis, de Toledo, Guillermo Alvarez, Armengol, José A.
Publicado 2020

NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression

por Sánchez-de-Diego, Cristina, Pedrazza, Leonardo, Pimenta-Lopes, Carolina, Martinez-Martinez, Arturo, Dahdah, Norma, Valer, José Antonio, Garcia-Roves, Pablo, Rosa, Jose Luis, Ventura, Francesc
Publicado 2020

HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress

por Sala-Gaston, Joan, Pedrazza, Leonardo, Ramirez, Juanma, Martinez-Martinez, Arturo, Rawlins, Lettie E., Baple, Emma L., Crosby, Andrew H., Mayor, Ugo, Ventura, Francesc, Rosa, Jose Luis
Publicado 2022

HERC1 deficiency causes osteopenia through transcriptional program dysregulation during bone remodeling

por Pedrazza, Leonardo, Martinez-Martinez, Arturo, Sánchez-de-Diego, Cristina, Valer, José Antonio, Pimenta-Lopes, Carolina, Sala-Gaston, Joan, Szpak, Michal, Tyler-Smith, Chris, Ventura, Francesc, Rosa, Jose Luis
Publicado 2023

Exenatide induces autophagy and prevents the cell regrowth in HepG2 cells

por Krause, Gabriele Catyana, Lima, Kelly Goulart, Levorse, Vitor, Haute, Gabriela Viegas, Gassen, Rodrigo Benedetti, Garcia, Maria Cláudia, Pedrazza, Leonardo, Donadio, Márcio Vinícius Fagundes, Luft, Carolina, de Oliveira, Jarbas Rodrigues
Publicado 2019

The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination

por Cubillos-Rojas, Monica, Schneider, Taiane, Hadjebi, Ouadah, Pedrazza, Leonardo, de Oliveira, Jarbas Rodrigues, Langa, Francina, Guénet, Jean-Louis, Duran, Joan, de Anta, Josep Maria, Alcántara, Soledad, Ruiz, Rocio, Pérez-Villegas, Eva María, Aguilar, Francisco J., Carrión, Ángel M., Armengol, Jose Angel, Baple, Emma, Crosby, Andrew H., Bartrons, Ramon, Ventura, Francesc, Rosa, Jose Luis
Publicado 2016