Phenotypic diversity drives paracrine drug tolerance

por Kuilman, Thomas, Peeper, Daniel S
Publicado 2017

Heterogeneity in functional genetic screens: friend or foe?

por Vredevoogd, David W., Peeper, Daniel S.
Publicado 2023

Epithelial-mesenchymal transition and senescence: two cancer-related processes are crossing paths

por Smit, Marjon A., Peeper, Daniel S.
Publicado 2010

Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival

por Iskit, Sedef, Schlicker, Andreas, Wessels, Lodewyk, Peeper, Daniel S.
Publicado 2015

SUMOylation of DRIL1 Directs Its Transcriptional Activity Towards Leukocyte Lineage-Specific Genes

por Prieur, Alexandre, Nacerddine, Karim, van Lohuizen, Maarten, Peeper, Daniel S.
Publicado 2009

Functional Characterization of Human Cancer-Derived TRKB Mutations

por Geiger, Thomas R., Song, Ji-Ying, Rosado, Aranzazu, Peeper, Daniel S.
Publicado 2011

Proteomics and Phosphoproteomics Profiling of Drug-Addicted BRAFi-Resistant Melanoma Cells

por Li, Bohui, Kong, Xiangjun, Post, Harm, Raaijmakers, Linsey, Peeper, Daniel S., Altelaar, Maarten
Publicado 2021

Integrated in vivo genetic and pharmacologic screening identifies co-inhibition of EGRF and ROCK as a potential treatment regimen for triple-negative breast cancer

por Iskit, Sedef, Lieftink, Cor, Halonen, Pasi, Shahrabi, Aida, Possik, Patricia A., Beijersbergen, Roderick L., Peeper, Daniel S.
Publicado 2016

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

por Gallenne, Tristan, Ross, Kenneth N., Visser, Nils L., Salony, Desmet, Christophe J., Wittner, Ben S., Wessels, Lodewyk F.A., Ramaswamy, Sridhar, Peeper, Daniel S.
Publicado 2017

FGFR1 Oncogenic Activation Reveals an Alternative Cell of Origin of SCLC in Rb1/p53 Mice

por Ferone, Giustina, Song, Ji-Ying, Krijgsman, Oscar, van der Vliet, Jan, Cozijnsen, Miranda, Semenova, Ekaterina A., Adams, David J., Peeper, Daniel, Berns, Anton
Publicado 2020

Massive reshaping of genome–nuclear lamina interactions during oncogene-induced senescence

por Lenain, Christelle, de Graaf, Carolyn A., Pagie, Ludo, Visser, Nils L., de Haas, Marcel, de Vries, Sandra S., Peric-Hupkes, Daniel, van Steensel, Bas, Peeper, Daniel S.
Publicado 2017

A genome‐wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS‐mutant melanoma

por Nagler, Adi, Vredevoogd, David W., Alon, Michal, Cheng, Phil F., Trabish, Sophie, Kalaora, Shelly, Arafeh, Rand, Goldin, Victoria, Levesque, Mitchell P., Peeper, Daniel S., Samuels, Yardena
Publicado 2019

ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

por Smit, Marjon A, Maddalo, Gianluca, Greig, Kylie, Raaijmakers, Linsey M, Possik, Patricia A, van Breukelen, Bas, Cappadona, Salvatore, Heck, Albert JR, Altelaar, AF Maarten, Peeper, Daniel S
Publicado 2014

Cancer Drug Addiction is Relayed by an ERK2-Dependent Phenotype Switch

por Kong, Xiangjun, Kuilman, Thomas, Shahrabi, Aida, Boshuizen, Julia, Kemper, Kristel, Song, Ji-Ying, Niessen, Hans W.M., Rozeman, Elisa A., Geukes Foppen, Marnix H., Blank, Christian U., Peeper, Daniel S.
Publicado 2017

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characterist...

por van der Hiel, Bernies, Haanen, John B.A.G., Stokkel, Marcel P.M., Peeper, Daniel S., Jimenez, Connie R., Beijnen, Jos H., van de Wiel, Bart A., Boellaard, Ronald, van den Eertwegh, Alfons J.M.
Publicado 2017

Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors

por Azimi, Alireza, Caramuta, Stefano, Seashore‐Ludlow, Brinton, Boström, Johan, Robinson, Jonathan L, Edfors, Fredrik, Tuominen, Rainer, Kemper, Kristel, Krijgsman, Oscar, Peeper, Daniel S, Nielsen, Jens, Hansson, Johan, Egyhazi Brage, Suzanne, Altun, Mikael, Uhlen, Mathias, Maddalo, Gianluca
Publicado 2018

SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response

por Ibáñez-Molero, Sofía, van Vliet, Alex, Pozniak, Joanna, Hummelink, Karlijn, Terry, Alexandra M., Monkhorst, Kim, Sanders, Joyce, Hofland, Ingrid, Landeloos, Ewout, Van Herck, Yannick, Bechter, Oliver, Kuilman, Thomas, Zhong, Weiwei, Marine, Jean-Christophe, Wessels, Lodewyk, Peeper, Daniel S.
Publicado 2022

CopywriteR: DNA copy number detection from off-target sequence data

por Kuilman, Thomas, Velds, Arno, Kemper, Kristel, Ranzani, Marco, Bombardelli, Lorenzo, Hoogstraat, Marlous, Nevedomskaya, Ekaterina, Xu, Guotai, de Ruiter, Julian, Lolkema, Martijn P, Ylstra, Bauke, Jonkers, Jos, Rottenberg, Sven, Wessels, Lodewyk F, Adams, David J, Peeper, Daniel S, Krijgsman, Oscar
Publicado 2015

Integrative epigenetic taxonomy of primary prostate cancer

por Stelloo, Suzan, Nevedomskaya, Ekaterina, Kim, Yongsoo, Schuurman, Karianne, Valle-Encinas, Eider, Lobo, João, Krijgsman, Oscar, Peeper, Daniel Simon, Chang, Seiwon Laura, Feng, Felix Yi-Chung, Wessels, Lodewyk Frederik Ary, Henrique, Rui, Jerónimo, Carmen, Bergman, Andries Marinus, Zwart, Wilbert
Publicado 2018

High-Throughput Assessment of Kinome-wide Activation States

por Schmidlin, Thierry, Debets, Donna O., van Gelder, Charlotte A.G.H., Stecker, Kelly E., Rontogianni, Stamatia, van den Eshof, Bart L., Kemper, Kristel, Lips, Esther H., van den Biggelaar, Maartje, Peeper, Daniel S., Heck, Albert J.R., Altelaar, Maarten
Publicado 2019