Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3

by Zhang, Jiazhen, Macartney, Thomas, Peggie, Mark, Cohen, Philip
Published 2017

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

by Zhang, Jiazhen, Clark, Kristopher, Lawrence, Toby, Peggie, Mark W., Cohen, Philip
Published 2014

The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser(358) in adipocytes

by Henriksson, Emma, Jones, Helena A., Patel, Kashyap, Peggie, Mark, Morrice, Nicholas, Sakamoto, Kei, Göransson, Olga
Published 2012

DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA

by Ordureau, Alban, Enesa, Karine, Nanda, Sambit, Le Francois, Brice, Peggie, Mark, Prescott, Alan, Albert, Paul R., Cohen, Philip
Published 2013

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

by Inesta-Vaquera, Francisco, Chaugule, Viduth K, Galloway, Alison, Chandler, Laurel, Rojas-Fernandez, Alejandro, Weidlich, Simone, Peggie, Mark, Cowling, Victoria H
Published 2018

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

by Shehata, Saifeldin N., Hunter, Roger W., Ohta, Eriko, Peggie, Mark W., Lou, Hua Jane, Sicheri, Frank, Zeqiraj, Elton, Turk, Benjamin E., Sakamoto, Kei
Published 2012

mRNA Cap Methylation in Pluripotency and Differentiation

by Grasso, Laura, Suska, Olga, Davidson, Lindsay, Gonatopoulos-Pournatzis, Thomas, Williamson, Ritchie, Wasmus, Lize, Wiedlich, Simone, Peggie, Mark, Stavridis, Marios P., Cowling, Victoria H.
Published 2016

Protein phosphatase 4 is phosphorylated and inactivated by Cdk in response to spindle toxins and interacts with γ-tubulin

by Voss, Martin, Campbell, Kathryn, Saranzewa, Nastja, Campbell, David G, Hastie, C James, Peggie, Mark W, Martin-Granados, Cristina, Prescott, Alan R, Cohen, Patricia TW
Published 2013

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

by Hunter, Roger W., Hughey, Curtis C., Lantier, Louise, Sundelin, Elias I., Peggie, Mark, Zeqiraj, Elton, Sicheri, Frank, Jessen, Niels, Wasserman, David H., Sakamoto, Kei
Published 2018

Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations

by Kumar, Atul, Tamjar, Jevgenia, Waddell, Andrew D, Woodroof, Helen I, Raimi, Olawale G, Shaw, Andrew M, Peggie, Mark, Muqit, Miratul MK, van Aalten, Daan MF
Published 2017

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

by Varshney, Dhaval, Petit, Alain-Pierre, Bueren-Calabuig, Juan A., Jansen, Chimed, Fletcher, Dan A., Peggie, Mark, Weidlich, Simone, Scullion, Paul, Pisliakov, Andrei V., Cowling, Victoria H.
Published 2016

Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity

by Kazlauskaite, Agne, Kelly, Van, Johnson, Clare, Baillie, Carla, Hastie, C. James, Peggie, Mark, Macartney, Thomas, Woodroof, Helen I., Alessi, Dario R., Pedrioli, Patrick G. A., Muqit, Miratul M. K.
Published 2014

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

by Lai, Yu‐Chiang, Kondapalli, Chandana, Lehneck, Ronny, Procter, James B, Dill, Brian D, Woodroof, Helen I, Gourlay, Robert, Peggie, Mark, Macartney, Thomas J, Corti, Olga, Corvol, Jean‐Christophe, Campbell, David G, Itzen, Aymelt, Trost, Matthias, Muqit, Miratul MK
Published 2015

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

by Patel, Kashyap, Foretz, Marc, Marion, Allison, Campbell, David G., Gourlay, Robert, Boudaba, Nadia, Tournier, Emilie, Titchenell, Paul, Peggie, Mark, Deak, Maria, Wan, Min, Kaestner, Klaus H., Göransson, Olga, Viollet, Benoit, Gray, Nathanael S., Birnbaum, Morris J., Sutherland, Calum, Sakamoto, Kei
Published 2014

Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis

by von Wilamowitz-Moellendorff, Alexander, Hunter, Roger W., García-Rocha, Mar, Kang, Li, López-Soldado, Iliana, Lantier, Louise, Patel, Kashyap, Peggie, Mark W., Martínez-Pons, Carlos, Voss, Martin, Calbó, Joaquim, Cohen, Patricia T.W., Wasserman, David H., Guinovart, Joan J., Sakamoto, Kei
Published 2013

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

by Kazlauskaite, Agne, Martínez-Torres, R Julio, Wilkie, Scott, Kumar, Atul, Peltier, Julien, Gonzalez, Alba, Johnson, Clare, Zhang, Jinwei, Hope, Anthony G, Peggie, Mark, Trost, Matthias, van Aalten, Daan MF, Alessi, Dario R, Prescott, Alan R, Knebel, Axel, Walden, Helen, Muqit, Miratul MK
Published 2015