Exquisitely Specific anti-KRAS Biodegraders Inform on the Cellular Prevalence of Nucleotide-Loaded States

por Lim, Shuhui, Khoo, Regina, Juang, Yu-Chi, Gopal, Pooja, Zhang, Huibin, Yeo, Constance, Peh, Khong Ming, Teo, Jinkai, Ng, Simon, Henry, Brian, Partridge, Anthony W.
Publicado 2020

Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling

por Lim, Shuhui, Boyer, Nicolas, Boo, Nicole, Huang, Chunhui, Venkatachalam, Gireedhar, Angela Juang, Yu-Chi, Garrigou, Michael, Kaan, Hung Yi Kristal, Duggal, Ruchia, Peh, Khong Ming, Sadruddin, Ahmad, Gopal, Pooja, Yuen, Tsz Ying, Ng, Simon, Kannan, Srinivasaraghavan, Brown, Christopher J., Verma, Chandra S., Orth, Peter, Peier, Andrea, Ge, Lan, Yu, Xiang, Bhatt, Bhavana, Chen, Feifei, Wang, Erjia, Li, Nianyu Jason, Gonzales, Raymond J., Stoeck, Alexander, Henry, Brian, Sawyer, Tomi K., Lane, David P., Johannes, Charles W., Biswas, Kaustav, Partridge, Anthony W.
Publicado 2021