Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences identical to potential, IgE – binding linear epitopes of allergen...

por Kleter, Gijs A, Peijnenburg, Ad ACM
Publicado 2002

Cyclosporin A induced toxicity in mouse liver slices is only slightly aggravated by Fxr-deficiency and co-occurs with upregulation of pro-inflammatory genes and downregulation of g...

por Szalowska, Ewa, Pronk, Tessa E., Peijnenburg, Ad ACM
Publicado 2015

Development of a Web-Based Toolbox to Support Quantitative In-Vitro-to-In-Vivo Extrapolations (QIVIVE) within Nonanimal Testing Strategies

por Punt, Ans, Pinckaers, Nicole, Peijnenburg, Ad, Louisse, Jochem
Publicado 2020

Health Considerations Regarding Horizontal Transfer of Microbial Transgenes Present in Genetically Modified Crops

por Kleter, Gijs A., Peijnenburg, Ad A. C. M., Aarts, Henk J. M.
Publicado 2005

Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes

por Szalowska, Ewa, Stoopen, Geert, Groot, Maria J, Hendriksen, Peter JM, Peijnenburg, Ad ACM
Publicado 2013

An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin

por Ruiz-Aracama, Ainhoa, Peijnenburg, Ad, Kleinjans, Jos, Jennen, Danyel, van Delft, Joost, Hellfrisch, Caroline, Lommen, Arjen
Publicado 2011

Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells

por Jennen, Danyel, Ruiz-Aracama, Ainhoa, Magkoufopoulou, Christina, Peijnenburg, Ad, Lommen, Arjen, van Delft, Joost, Kleinjans, Jos
Publicado 2011

Identification of Cisplatin-Regulated Metabolic Pathways in Pluripotent Stem Cells

por von Stechow, Louise, Ruiz-Aracama, Ainhoa, van de Water, Bob, Peijnenburg, Ad, Danen, Erik, Lommen, Arjen
Publicado 2013

Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in...

por Louisse, Jochem, Rijkers, Deborah, Stoopen, Geert, Janssen, Aafke, Staats, Martijn, Hoogenboom, Ron, Kersten, Sander, Peijnenburg, Ad
Publicado 2020

Model Steatogenic Compounds (Amiodarone, Valproic Acid, and Tetracycline) Alter Lipid Metabolism by Different Mechanisms in Mouse Liver Slices

por Szalowska, Ewa, van der Burg, Bart, Man, Hai-Yen, Hendriksen, Peter J. M., Peijnenburg, Ad A. C. M.
Publicado 2014

Allermatch™, a webtool for the prediction of potential allergenicity according to current FAO/WHO Codex alimentarius guidelines

por Fiers, Mark WEJ, Kleter, Gijs A, Nijland, Herman, Peijnenburg, Ad ACM, Nap, Jan Peter, van Ham, Roeland CHJ
Publicado 2004

New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs

por Fragki, Styliani, Louisse, Jochem, Bokkers, Bas, Luijten, Mirjam, Peijnenburg, Ad, Rijkers, Deborah, Piersma, Aldert H., Zeilmaker, Marco J.
Publicado 2023

Feasibility of a liver transcriptomics approach to assess bovine treatment with the prohormone dehydroepiandrosterone (DHEA)

por Rijk, Jeroen CW, Peijnenburg, Ad ACM, Hendriksen, Peter JM, Van Hende, Johan M, Groot, Maria J, Nielen, Michel WF
Publicado 2010

The impact of PPARα activation on whole genome gene expression in human precision cut liver slices

por Janssen, Aafke W.F., Betzel, Bark, Stoopen, Geert, Berends, Frits J., Janssen, Ignace M., Peijnenburg, Ad A., Kersten, Sander
Publicado 2015

Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells...

por Janssen, Aafke W. F., Duivenvoorde, Loes P. M., Rijkers, Deborah, Nijssen, Rosalie, Peijnenburg, Ad A. C. M., van der Zande, Meike, Louisse, Jochem
Publicado 2020

Bioassay-directed analysis-based identification of relevant pyrrolizidine alkaloids

por Louisse, Jochem, Mulder, Patrick P. J., Gerssen, Arjen, Stoopen, Geert, Rijkers, Deborah, van de Schans, Milou G. M., Peijnenburg, Ad A. C. M.
Publicado 2022

Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells

por Janssen, Aafke W. F., Louisse, Jochem, Rijkers, Deborah, Pinckaers, Nicole E. T., Hoekstra, Sjoerdtje A., Hoogenboom, Ron L. A. P., Peijnenburg, Ad A. C. M., Beekmann, Karsten
Publicado 2022

Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells

por Louisse, Jochem, Fragki, Styliani, Rijkers, Deborah, Janssen, Aafke, van Dijk, Bas, Leenders, Liz, Staats, Martijn, Bokkers, Bas, Zeilmaker, Marco, Piersma, Aldert, Luijten, Mirjam, Hoogenboom, Ron, Peijnenburg, Ad
Publicado 2023

Polyphenol Composition, Antioxidant Activity and Cytotoxicity of Seeds from Two Underexploited Wild Licania Species: L. rigida and L. tomentosa

por Parra Pessoa, Igor, Lopes Neto, José Joaquim, Silva de Almeida, Thiago, Felipe Farias, Davi, Vieira, Leonardo Rogério, Lima de Medeiros, Jackeline, Augusti Boligon, Aline, Peijnenburg, Ad, Castelar, Ivan, Fontenele Urano Carvalho, Ana
Publicado 2016

Current Insights into Monitoring, Bioaccumulation, and Potential Health Effects of Microplastics Present in the Food Chain

por van Raamsdonk, Leonard W. D., van der Zande, Meike, Koelmans, Albert A., Hoogenboom, Ron L. A. P., Peters, Ruud J. B., Groot, Maria J., Peijnenburg, Ad A. C. M., Weesepoel, Yannick J. A.
Publicado 2020