Poly(ADP-ribose) polymerase inhibition with HYDAMTIQ reduces allergen-induced asthma-like reaction, bronchial hyper-reactivity and airway remodelling

por Lucarini, Laura, Pini, Alessandro, Gerace, Elisabetta, Pellicciari, Roberto, Masini, Emanuela, Moroni, Flavio
Publicado 2014

Synthesis and Quantitative Structure-Property Relationships of Side Chain-Modified Hyodeoxycholic Acid Derivatives

por Sabbatini, Paola, Filipponi, Paolo, Sardella, Roccaldo, Natalini, Benedetto, Nuti, Roberto, Macchiarulo, Antonio, Pellicciari, Roberto, Gioiello, Antimo
Publicado 2013

Structural Basis of Human Dimeric α-Amino-β-Carboxymuconate-ε-Semialdehyde Decarboxylase Inhibition With TES-1025

por Cianci, Michele, Giacchè, Nicola, Cialabrini, Lucia, Carotti, Andrea, Liscio, Paride, Rosatelli, Emiliano, De Franco, Francesca, Gasparrini, Massimiliano, Robertson, Janet, Amici, Adolfo, Raffaelli, Nadia, Pellicciari, Roberto
Publicado 2022

The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression

por Bijsmans, Ingrid T. G. W., Guercini, Chiara, Ramos Pittol, José M., Omta, Wienand, Milona, Alexandra, Lelieveld, Daphne, Egan, David A., Pellicciari, Roberto, Gioiello, Antimo, van Mil, Saskia W. C.
Publicado 2015

Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists

por Pérez-Gordillo, Felipe Luis, Serrano-Morillas, Natalia, Acosta-García, Luz Marina, Aranda, María Teresa, Passeri, Daniela, Pellicciari, Roberto, Pérez de Vega, María Jesús, González-Muñiz, Rosario, Alvarez de la Rosa, Diego, Martín-Martínez, Mercedes
Publicado 2023

Central anorexigenic actions of bile acids are mediated by TGR5

por Perino, Alessia, Velázquez-Villegas, Laura. A., Bresciani, Nadia, Sun, Yu, Huang, Qingyao, Fénelon, Valérie S., Castellanos-Jankiewicz, Ashley, Zizzari, Philippe, Bruschetta, Giuseppe, Jin, Sungho, Baleisyte, Aiste, Gioiello, Antimo, Pellicciari, Roberto, Ivanisevic, Julijana, Schneider, Bernard L., Diano, Sabrina, Cota, Daniela, Schoonjans, Kristina
Publicado 2021

Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib

por Bagnolini, Greta, Milano, Domenico, Manerba, Marcella, Schipani, Fabrizio, Ortega, Jose Antonio, Gioia, Dario, Falchi, Federico, Balboni, Andrea, Farabegoli, Fulvia, De Franco, Francesca, Robertson, Janet, Pellicciari, Roberto, Pallavicini, Isabella, Peri, Sebastiano, Minucci, Saverio, Girotto, Stefania, Di Stefano, Giuseppina, Roberti, Marinella, Cavalli, Andrea
Publicado 2020

De novo NAD(+) synthesis enhances mitochondrial function and improves health

por Katsyuba, Elena, Mottis, Adrienne, Zietak, Marika, De Franco, Francesca, van der Velpen, Vera, Gariani, Karim, Ryu, Dongryeol, Cialabrini, Lucia, Matilainen, Olli, Liscio, Paride, Giacchè, Nicola, Stokar-Regenscheit, Nadine, Legouis, David, de Seigneux, Sophie, Ivanisevic, Julijana, Raffaelli, Nadia, Schoonjans, Kristina, Pellicciari, Roberto, Auwerx, Johan
Publicado 2018

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

por Bartolini, Desirée, De Franco, Francesca, Torquato, Pierangelo, Marinelli, Rita, Cerra, Bruno, Ronchetti, Riccardo, Schon, Arne, Fallarino, Francesca, De Luca, Antonella, Bellezza, Guido, Ferri, Ivana, Sidoni, Angelo, Walton, William G., Pellock, Samuel J., Redinbo, Matthew R., Mani, Sridhar, Pellicciari, Roberto, Gioiello, Antimo, Galli, Francesco
Publicado 2020

Ablation of liver Fxr results in an increased colonic mucus barrier in mice

por Ijssennagger, Noortje, van Rooijen, Kristel S., Magnúsdóttir, Stefanía, Ramos Pittol, José M., Willemsen, Ellen C.L., de Zoete, Marcel R., Baars, Matthijs J.D., Stege, Paul B., Colliva, Carolina, Pellicciari, Roberto, Youssef, Sameh A., de Bruin, Alain, Vercoulen, Yvonne, Kuipers, Folkert, van Mil, Saskia W.C.
Publicado 2021

First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53

por Nowak, Radosław P., Tumber, Anthony, Hendrix, Eline, Ansari, Mohammad Salik Zeya, Sabatino, Manuela, Antonini, Lorenzo, Andrijes, Regina, Salah, Eidarus, Mautone, Nicola, Pellegrini, Francesca Romana, Simelis, Klemensas, Kawamura, Akane, Johansson, Catrine, Passeri, Daniela, Pellicciari, Roberto, Ciogli, Alessia, Del Bufalo, Donatella, Ragno, Rino, Coleman, Mathew L., Trisciuoglio, Daniela, Mai, Antonello, Oppermann, Udo, Schofield, Christopher J., Rotili, Dante
Publicado 2021

Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication

por Gargaro, Marco, Scalisi, Giulia, Manni, Giorgia, Briseño, Carlos G., Bagadia, Prachi, Durai, Vivek, Theisen, Derek J., Kim, Sunkyung, Castelli, Marilena, Xu, Chenling A., zu Hörste, Gerd Meyer, Servillo, Giuseppe, Della Fazia, Maria A., Mencarelli, Giulia, Ricciuti, Doriana, Padiglioni, Eleonora, Giacchè, Nicola, Colliva, Carolina, Pellicciari, Roberto, Calvitti, Mario, Zelante, Teresa, Fuchs, Dietmar, Orabona, Ciriana, Boon, Louis, Bessede, Alban, Colonna, Marco, Puccetti, Paolo, Murphy, Theresa L., Murphy, Kenneth M., Fallarino, Francesca
Publicado 2022