Update on Lynch syndrome genomics

por Peltomäki, Päivi
Publicado 2016

Mutations Associated with HNPCC Predisposition — Update of ICG-HNPCC/INSiGHT Mutation Database

por Peltomäki, Päivi, Vasen, Hans
Publicado 2004

LINE-1 hypomethylation in familial and sporadic cancer

por Pavicic, Walter, Joensuu, Emmi I., Nieminen, Taina, Peltomäki, Päivi
Publicado 2012

From APC to the genetics of hereditary and familial colon cancer syndromes

por Olkinuora, Alisa P, Peltomäki, Päivi T, Aaltonen, Lauri A, Rajamäki, Kristiina
Publicado 2021

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells

por Nair, Vidhya A, Valo, Satu, Peltomäki, Päivi, Bajbouj, Khuloud, Abdel-Rahman, Wael M.
Publicado 2020

Pseudoexons provide a mechanism for allele-specific expression of APC in familial adenomatous polyposis

por Nieminen, Taina T., Pavicic, Walter, Porkka, Noora, Kankainen, Matti, Järvinen, Heikki J., Lepistö, Anna, Peltomäki, Päivi
Publicado 2016

Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations

por Porkka, Noora, Valo, Satu, Nieminen, Taina T., Olkinuora, Alisa, Mäki-Nevala, Satu, Eldfors, Samuli, Peltomäki, Päivi
Publicado 2017

Identification of subgroup-specific miRNA patterns by epigenetic profiling of sporadic and Lynch syndrome-associated colorectal and endometrial carcinoma

por Kaur, Sippy, Lotsari, Johanna E, Al-Sohaily, Sam, Warusavitarne, Janindra, Kohonen-Corish, Maija RJ, Peltomäki, Päivi
Publicado 2015

DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

por Valo, Satu, Kaur, Sippy, Ristimäki, Ari, Renkonen-Sinisalo, Laura, Järvinen, Heikki, Mecklin, Jukka-Pekka, Nyström, Minna, Peltomäki, Päivi
Publicado 2015

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas

por Porkka, Noora K., Olkinuora, Alisa, Kuopio, Teijo, Ahtiainen, Maarit, Eldfors, Samuli, Almusa, Henrikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2020

Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

por Olkinuora, Alisa, Gylling, Annette, Almusa, Henrikki, Eldfors, Samuli, Lepistö, Anna, Mecklin, Jukka-Pekka, Nieminen, Taina Tuulikki, Peltomäki, Päivi
Publicado 2020

Testing for Lynch Syndrome in Endometrial Carcinoma: From Universal to Age-Selective MLH1 Methylation Analysis

por Pasanen, Annukka, Loukovaara, Mikko, Kaikkonen, Elina, Olkinuora, Alisa, Pylvänäinen, Kirsi, Alhopuro, Pia, Peltomäki, Päivi, Mecklin, Jukka-Pekka, Bützow, Ralf
Publicado 2022

Body Weight, Physical Activity, and Risk of Cancer in Lynch Syndrome

por Sievänen, Tero, Törmäkangas, Timo, Laakkonen, Eija K., Mecklin, Jukka-Pekka, Pylvänäinen, Kirsi, Seppälä, Toni T., Peltomäki, Päivi, Sipilä, Sarianna, Sillanpää, Elina
Publicado 2021

Cancer-Predicting Gene Expression Changes in Colonic Mucosa of Western Diet Fed Mlh1 (+/-) Mice

por Pussila, Marjaana, Sarantaus, Laura, Dermadi Bebek, Denis, Valo, Satu, Reyhani, Nima, Ollila, Saara, Päivärinta, Essi, Peltomäki, Päivi, Mutanen, Marja, Nyström, Minna
Publicado 2013

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

por Niskakoski, Anni, Kaur, Sippy, Staff, Synnöve, Renkonen-Sinisalo, Laura, Lassus, Heini, Järvinen, Heikki J, Mecklin, Jukka-Pekka, Bützow, Ralf, Peltomäki, Päivi
Publicado 2015

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription

por Abdel-Rahman, Wael M., Lotsari-Salomaa, Johanna E., Kaur, Sippy, Niskakoski, Anni, Knuutila, Sakari, Järvinen, Heikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2016

Biallelic germline nonsense variant of MLH3 underlies polyposis predisposition

por Olkinuora, Alisa, Nieminen, Taina T., Mårtensson, Emma, Rohlin, Anna, Ristimäki, Ari, Koskenvuo, Laura, Lepistö, Anna, Gebre-Medhin, Samuel, Nordling, Margareta, Peltomäki, Päivi
Publicado 2018

Immunoprofiles and DNA Methylation of Inflammatory Marker Genes in Ulcerative Colitis-Associated Colorectal Tumorigenesis

por Mäki-Nevala, Satu, Ukwattage, Sanjeevi, Wirta, Erkki-Ville, Ahtiainen, Maarit, Ristimäki, Ari, Seppälä, Toni T., Lepistö, Anna, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Publicado 2021

Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers

por Ukkola, Iiris, Nummela, Pirjo, Kero, Mia, Tammio, Hanna, Tuominen, Jenni, Kairisto, Veli, Kallajoki, Markku, Haglund, Caj, Peltomäki, Päivi, Kytölä, Soili, Ristimäki, Ari
Publicado 2022

Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer

por Pussila, Marjaana, Törönen, Petri, Einarsdottir, Elisabet, Katayama, Shintaro, Krjutškov, Kaarel, Holm, Liisa, Kere, Juha, Peltomäki, Päivi, Mäkinen, Markus J, Linden, Jere, Nyström, Minna
Publicado 2018