Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wld(s))

por Wishart, Thomas M, Pemberton, Helen N, James, Sally R, McCabe, Chris J, Gillingwater, Thomas H
Publicado 2008

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

por Kanu, Nnennaya, Zhang, Tianyi, Burrell, Rebecca A., Chakraborty, Atanu, Cronshaw, Janet, Da Costa, Clive, Grönroos, Eva, Pemberton, Helen N., Anderton, Emma, Gonzalez, Laure, Sabbioneda, Simone, Ulrich, Helle D., Swanton, Charles, Behrens, Axel
Publicado 2015

A Flexible, Pooled CRISPR Library for Drug Development Screens

por Blanck, Maximilian, Budnik-Zawilska, Milka B., Lenger, Steven R., McGonigle, John E., Martin, Glynn R.A., le Sage, Carlos, Lawo, Steffen, Pemberton, Helen N., Tiwana, Gaganpreet S., Sorrell, David A., Cross, Benedict C.S.
Publicado 2020

Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells

por Nikkilä, Jenni, Kumar, Rahul, Campbell, James, Brandsma, Inger, Pemberton, Helen N, Wallberg, Fredrik, Nagy, Kinga, Scheer, Ildikó, Vertessy, Beata G, Serebrenik, Artur A, Monni, Valentina, Harris, Reuben S, Pettitt, Stephen J, Ashworth, Alan, Lord, Christopher J
Publicado 2017

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

por Williamson, Chris T., Miller, Rowan, Pemberton, Helen N., Jones, Samuel E., Campbell, James, Konde, Asha, Badham, Nicholas, Rafiq, Rumana, Brough, Rachel, Gulati, Aditi, Ryan, Colm J., Francis, Jeff, Vermulen, Peter B., Reynolds, Andrew R., Reaper, Philip M., Pollard, John R., Ashworth, Alan, Lord, Christopher J.
Publicado 2016

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells

por Pettitt, Stephen J., Krastev, Dragomir B., Pemberton, Helen N., Fontebasso, Yari, Frankum, Jessica, Rehman, Farah L., Brough, Rachel, Song, Feifei, Bajrami, Ilirjana, Rafiq, Rumana, Wallberg, Fredrik, Kozarewa, Iwanka, Fenwick, Kerry, Armisen-Garrido, Javier, Swain, Amanda, Gulati, Aditi, Campbell, James, Ashworth, Alan, Lord, Christopher J.
Publicado 2017

MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation

por O'Loghlen, Ana, Muñoz-Cabello, Ana M., Gaspar-Maia, Alexandre, Wu, Hsan-Au, Banito, Ana, Kunowska, Natalia, Racek, Tomas, Pemberton, Helen N., Beolchi, Patrizia, Lavial, Fabrice, Masui, Osamu, Vermeulen, Michiel, Carroll, Thomas, Graumann, Johannes, Heard, Edith, Dillon, Niall, Azuara, Veronique, Snijders, Ambrosius P., Peters, Gordon, Bernstein, Emily, Gil, Jesus
Publicado 2012

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

por Pettitt, Stephen J., Krastev, Dragomir B., Brandsma, Inger, Dréan, Amy, Song, Feifei, Aleksandrov, Radoslav, Harrell, Maria I., Menon, Malini, Brough, Rachel, Campbell, James, Frankum, Jessica, Ranes, Michael, Pemberton, Helen N., Rafiq, Rumana, Fenwick, Kerry, Swain, Amanda, Guettler, Sebastian, Lee, Jung-Min, Swisher, Elizabeth M., Stoynov, Stoyno, Yusa, Kosuke, Ashworth, Alan, Lord, Christopher J.
Publicado 2018

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

por Campbell, James, Ryan, Colm J., Brough, Rachel, Bajrami, Ilirjana, Pemberton, Helen N., Chong, Irene Y., Costa-Cabral, Sara, Frankum, Jessica, Gulati, Aditi, Holme, Harriet, Miller, Rowan, Postel-Vinay, Sophie, Rafiq, Rumana, Wei, Wenbin, Williamson, Chris T., Quigley, David A., Tym, Joe, Al-Lazikani, Bissan, Fenton, Timothy, Natrajan, Rachael, Strauss, Sandra J., Ashworth, Alan, Lord, Christopher J.
Publicado 2016

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

por Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D. G., Bajrami, Ilirjana, Campbell, James, Chong, Irene Y., Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim, Frankum, Jessica, Jones, Samuel E., Menon, Malini, Miller, Rowan, Pemberton, Helen N., Postel-Vinay, Sophie, Rafiq, Rumana, Selfe, Joanna L., von Kriegsheim, Alex, Munoz, Amaya Garcia, Rodriguez, Javier, Shipley, Janet, van der Graaf, Winette T. A., Williamson, Chris T., Ryan, Colm J., Pettitt, Stephen, Ashworth, Alan, Strauss, Sandra J., Lord, Christopher J.
Publicado 2018

Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

por Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D. G., Bajrami, Ilirjana, Campbell, James, Chong, Irene Y., Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim, Frankum, Jessica, Jones, Samuel E., Menon, Malini, Miller, Rowan, Pemberton, Helen N., Postel-Vinay, Sophie, Rafiq, Rumana, Selfe, Joanna L., von Kriegsheim, Alex, Munoz, Amaya Garcia, Rodriguez, Javier, Shipley, Janet, van der Graaf, Winette T. A., Williamson, Chris T., Ryan, Colm J., Pettitt, Stephen, Ashworth, Alan, Strauss, Sandra J., Lord, Christopher J.
Publicado 2018

SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response

por Bland, Philip, Saville, Harry, Wai, Patty T., Curnow, Lucinda, Muirhead, Gareth, Nieminuszczy, Jadwiga, Ravindran, Nivedita, John, Marie Beatrix, Hedayat, Somaieh, Barker, Holly E., Wright, James, Yu, Lu, Mavrommati, Ioanna, Read, Abigail, Peck, Barrie, Allen, Mark, Gazinska, Patrycja, Pemberton, Helen N., Gulati, Aditi, Nash, Sarah, Noor, Farzana, Guppy, Naomi, Roxanis, Ioannis, Pratt, Guy, Oldreive, Ceri, Stankovic, Tatjana, Barlow, Samantha, Kalirai, Helen, Coupland, Sarah E., Broderick, Ronan, Alsafadi, Samar, Houy, Alexandre, Stern, Marc-Henri, Pettit, Stephen, Choudhary, Jyoti S., Haider, Syed, Niedzwiedz, Wojciech, Lord, Christopher J., Natrajan, Rachael
Publicado 2023