CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis

por Pender, Michael P.
Publicado 2012

The Essential Role of Epstein-Barr Virus in the Pathogenesis of Multiple Sclerosis

por Pender, Michael P.
Publicado 2011

Hypothesis: bipolar disorder is an Epstein–Barr virus‐driven chronic autoimmune disease – implications for immunotherapy

por Pender, Michael P
Publicado 2020

Epstein–Barr virus and multiple sclerosis: potential opportunities for immunotherapy

por Pender, Michael P, Burrows, Scott R
Publicado 2014

Reactivity to Novel Autoantigens in Patients with Coexisting Central Nervous System Demyelinating Disease and Autoimmune Thyroid Disease

por Greer, Judith M., Broadley, Simon, Pender, Michael P.
Publicado 2017

Correlation Between Anti-Myelin Proteolipid Protein (PLP) Antibodies and Disease Severity in Multiple Sclerosis Patients With PLP Response-Permissive HLA Types

por Greer, Judith M., Trifilieff, Elisabeth, Pender, Michael P.
Publicado 2020

Decreased CD8(+ )T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes

por Pender, Michael P, Csurhes, Peter A, Pfluger, Casey MM, Burrows, Scott R
Publicado 2011

Deficiency of CD8(+) effector memory T cells is an early and persistent feature of multiple sclerosis

por Pender, Michael P, Csurhes, Peter A, Pfluger, Casey MM, Burrows, Scott R
Publicado 2014

Defective T-cell control of Epstein–Barr virus infection in multiple sclerosis

por Pender, Michael P, Csurhes, Peter A, Burrows, Jacqueline M, Burrows, Scott R
Publicado 2017

Defective T-cell control of Epstein–Barr virus infection in multiple sclerosis

por Pender, Michael P, Csurhes, Peter A, Burrows, Jacqueline M, Burrows, Scott R
Publicado 2017

Reduced IκB-α Protein Levels in Peripheral Blood Cells of Patients with Multiple Sclerosis—A Possible Cause of Constitutive NF-κB Activation

por Yan, Jun, McCombe, Pamela A., Pender, Michael P., Greer, Judith M.
Publicado 2020

CD8 T cell deficiency impairs control of Epstein–Barr virus and worsens with age in multiple sclerosis

por Pender, Michael P, Csurhes, Peter A, Pfluger, Casey M M, Burrows, Scott R
Publicado 2011

PLP1 Mutations in Patients with Multiple Sclerosis: Identification of a New Mutation and Potential Pathogenicity of the Mutations

por Cloake, Nancy C., Yan, Jun, Aminian, Atefeh, Pender, Michael P., Greer, Judith M.
Publicado 2018

Correlations between macrophage/microglial activation marker sTREM-2 and measures of T-cell activation, neuroaxonal damage and disease severity in multiple sclerosis

por Ioannides, Zara A, Csurhes, Peter A, Swayne, Andrew, Foubert, Philippe, Aftab, Blake T, Pender, Michael P
Publicado 2021

Interleukin-6 Gene Promoter-572 C Allele may Play a Role in Rate of Disease Progression in Multiple Sclerosis

por Yan, Jun, Liu, Jia, Lin, Clement Yihao, Csurhes, Peter A., Pender, Michael P., McCombe, Pamela A., Greer, Judith M.
Publicado 2012

Epstein–Barr virus-specific adoptive immunotherapy for progressive multiple sclerosis

por Pender, Michael P, Csurhes, Peter A, Smith, Corey, Beagley, Leone, Hooper, Kaye D, Raj, Meenakshi, Coulthard, Alan, Burrows, Scott R, Khanna, Rajiv
Publicado 2014

Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies

por Bar-Or, Amit, Pender, Michael P., Khanna, Rajiv, Steinman, Lawrence, Hartung, Hans-Peter, Maniar, Tap, Croze, Ed, Aftab, Blake T., Giovannoni, Gavin, Joshi, Manher A.
Publicado 2020

Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies: (Trends in Molecular Medicine, 26:3 p:296-310, 2020)

por Bar-Or, Amit, Pender, Michael P., Khanna, Rajiv, Steinman, Lawrence, Hartung, Hans-Peter, Maniar, Tap, Croze, Ed, Aftab, Blake T., Giovannoni, Gavin, Joshi, Manher A.
Publicado 2021

Sustained Clinical Improvement in a Subset of Patients With Progressive Multiple Sclerosis Treated With Epstein–Barr Virus-Specific T Cell Therapy

por Ioannides, Zara A., Csurhes, Peter A., Douglas, Nanette L., Mackenroth, Gem, Swayne, Andrew, Thompson, Kate M., Hopkins, Tracey J., Green, Kerryn A., Blum, Stefan, Hooper, Kaye D., Wyssusek, Kerstin H., Coulthard, Alan, Pender, Michael P.
Publicado 2021

Epstein-Barr virus–specific T cell therapy for progressive multiple sclerosis

por Pender, Michael P., Csurhes, Peter A., Smith, Corey, Douglas, Nanette L., Neller, Michelle A., Matthews, Katherine K., Beagley, Leone, Rehan, Sweera, Crooks, Pauline, Hopkins, Tracey J., Blum, Stefan, Green, Kerryn A., Ioannides, Zara A., Swayne, Andrew, Aftab, Blake T., Hooper, Kaye D., Burrows, Scott R., Thompson, Kate M., Coulthard, Alan, Khanna, Rajiv
Publicado 2020