Calpain-Mediated Mitochondrial Damage: An Emerging Mechanism Contributing to Cardiac Disease

por Zhang, Mengxiao, Wang, Grace, Peng, Tianqing
Publicado 2021

Protective role of endothelial calpain knockout in lipopolysaccharide-induced acute kidney injury via attenuation of the p38-iNOS pathway and NO/ROS production

por Liu, Zhifeng, Ji, Jingjing, Zheng, Dong, Su, Lei, Peng, Tianqing, Tang, Jing
Publicado 2020

Deficiency of Rac1 Blocks NADPH Oxidase Activation, Inhibits Endoplasmic Reticulum Stress, and Reduces Myocardial Remodeling in a Mouse Model of Type 1 Diabetes

por Li, Jianmin, Zhu, Huaqing, Shen, E, Wan, Li, Arnold, J. Malcolm O., Peng, Tianqing
Publicado 2010

Administration of losartan preserves cardiomyocyte size and prevents myocardial dysfunction in tail-suspended mice by inhibiting p47(phox) phosphorylation, NADPH oxidase activation...

por Liang, Liwen, Yuan, Wenyi, Qu, Lina, Li, Huili, Zhang, Lulu, Fan, Guo-Chang, Peng, Tianqing
Publicado 2019

Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice

por Zhang, Mengxiao, Zhong, Huiting, Cao, Ting, Huang, Yifan, Ji, Xiaoyun, Fan, Guo-Chang, Peng, Tianqing
Publicado 2022

Tsg101 Is Involved in the Sorting and Re-Distribution of Glucose Transporter-4 to the Sarcolemma Membrane of Cardiac Myocytes

por Essandoh, Kobina, Deng, Shan, Wang, Xiaohong, Li, Yutian, Li, Qianqian, Mu, Xingjiang, Peng, Tianqing, Fan, Guo-Chang
Publicado 2020

Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

por Shen, E., Li, Yanwen, Li, Ying, Shan, Limei, Zhu, Huaqing, Feng, Qingping, Arnold, J. Malcolm O., Peng, Tianqing
Publicado 2009

Hsp20 Functions as a Novel Cardiokine in Promoting Angiogenesis via Activation of VEGFR2

por Zhang, Xiaowei, Wang, Xiaohong, Zhu, Hongyan, Kranias, Evangelia G., Tang, Yaoliang, Peng, Tianqing, Chang, Jiang, Fan, Guo-Chang
Publicado 2012

Myeloid cell-specific deletion of Capns1 prevents macrophage polarization toward the M1 phenotype and reduces interstitial lung disease in the bleomycin model of systemic sclerosis

por Zhang, Li, Zheng, Dong, Yan, Yuemei, Yu, Yong, Chen, Ruizhen, Li, Zheng, Greer, Peter A., Peng, Tianqing, Wang, Qiang
Publicado 2022

Enhancing Specific-Antibody Production to the ragB Vaccine with GITRL That Expand Tfh, IFN-γ(+) T Cells and Attenuates Porphyromonas gingivalis Infection in Mice

por Zheng, Dong, Sun, Qiang, Su, Zhaoliang, Kong, Fanzhi, Shi, Xiaoju, Tong, Jia, Shen, Pei, Peng, Tianqing, Wang, Shengjun, Xu, Huaxi
Publicado 2013

In Vivo Delivery of Adenoviral Vector Containing Interleukin-17 Receptor A Reduces Cardiac Remodeling and Improves Myocardial Function in Viral Myocarditis Leading to Dilated Cardi...

por Xie, Yuquan, Li, Minghui, Wang, Xinggang, Zhang, Xian, Peng, Tianqing, Yang, Yingzhen, Zou, Yunzeng, Ge, Junbo, Chen, Haozhu, Chen, Ruizhen
Publicado 2013

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

por Li, Ying, Ma, Jian, Zhu, Huaqing, Singh, Manpreet, Hill, David, Greer, Peter A., Arnold, J. Malcolm, Abel, E. Dale, Peng, Tianqing
Publicado 2011

Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes

por Chen, Bainian, Zhao, Qing, Ni, Rui, Tang, Futian, Shan, Limei, Cepinskas, Inga, Cepinskas, Gediminas, Wang, Wang, Schiller, Peter W, Peng, Tianqing
Publicado 2014

Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy

por Wang, Jinxi, Ciampa, Grace, Zheng, Dong, Shi, Qian, Chen, Biyi, Abel, E. Dale, Peng, Tianqing, Hall, Duane D., Song, Long-Sheng
Publicado 2021

MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetes

por Cao, Ting, Ni, Rui, Ding, Weimin, Ji, Xiaoyun, Li, Lan, Liao, Guangneng, Lu, Yanrong, Fan, Guo-Chang, Zhang, Zhuxu, Peng, Tianqing
Publicado 2022

Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation via Jagged...

por Chen, Rong, Zhang, Shiqing, Liu, Fang, Xia, Lin, Wang, Chong, Sandoghchian Shotorbani, Siamak, Xu, Huaxi, Chakrabarti, Subrata, Peng, Tianqing, Su, Zhaoliang
Publicado 2023

Calpain activation mediates microgravity-induced myocardial abnormalities in mice via p38 and ERK1/2 MAPK pathways

por Liang, Liwen, Li, Huili, Cao, Ting, Qu, Lina, Zhang, Lulu, Fan, Guo-Chang, Greer, Peter A., Li, Jianmin, Jones, Douglas L., Peng, Tianqing
Publicado 2021

Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages

por Li, Qianqian, Li, Yutian, Huang, Wei, Wang, Xiaohong, Liu, Zhenling, Chen, Jing, Fan, Yanbo, Peng, Tianqing, Sadayappan, Sakthivel, Wang, Yigang, Fan, Guo-Chang
Publicado 2022

Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial Sepsis

por Wang, Xiaohong, Gu, Haitao, Qin, Dongze, Yang, Liwang, Huang, Wei, Essandoh, Kobina, Wang, Yigang, Caldwell, Charles C., Peng, Tianqing, Zingarelli, Basilia, Fan, Guo-Chang
Publicado 2015

GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype

por Wang, Lu, Li, Yutian, Wang, Xiaohong, Wang, Peng, Essandoh, Kobina, Cui, Shunan, Huang, Wei, Mu, Xingjiang, Liu, Zhenling, Wang, Yigang, Peng, Tianqing, Fan, Guo-Chang
Publicado 2020