Structural Perspective on Revealing and Altering Molecular Functions of Genetic Variants Linked with Diseases

por Peng, Yunhui, Alexov, Emil, Basu, Sankar
Publicado 2019

Revealing the Effects of Missense Mutations Causing Snyder-Robinson Syndrome on the Stability and Dimerization of Spermine Synthase

por Peng, Yunhui, Norris, Joy, Schwartz, Charles, Alexov, Emil
Publicado 2016

Computational Investigation of the Missense Mutations in DHCR7 Gene Associated with Smith-Lemli-Opitz Syndrome

por Peng, Yunhui, Myers, Rebecca, Zhang, Wenxing, Alexov, Emil
Publicado 2018

Novel Genetic Markers for Early Detection of Elevated Breast Cancer Risk in Women

por Wu, Bohua, Peng, Yunhui, Eggert, Julia, Alexov, Emil
Publicado 2019

E-hooks provide guidance and a soft landing for the microtubule binding domain of dynein

por Tajielyato, Nayere, Li, Lin, Peng, Yunhui, Alper, Joshua, Alexov, Emil
Publicado 2018

Data sets on human histone interaction networks

por Peng, Yunhui, Markov, Yaroslav, Goncearenco, Alexander, Landsman, David, Panchenko, Anna R.
Publicado 2020

Binding of regulatory proteins to nucleosomes is modulated by dynamic histone tails

por Peng, Yunhui, Li, Shuxiang, Onufriev, Alexey, Landsman, David, Panchenko, Anna R.
Publicado 2021

Gaussian-Based Smooth Dielectric Function: A Surface-Free Approach for Modeling Macromolecular Binding in Solvents

por Chakravorty, Arghya, Jia, Zhe, Peng, Yunhui, Tajielyato, Nayere, Wang, Lisi, Alexov, Emil
Publicado 2018

DFMD: Fast and Effective DelPhiForce Steered Molecular Dynamics Approach to Model Ligand Approach Toward a Receptor: Application to Spermine Synthase Enzyme

por Peng, Yunhui, Yang, Ye, Li, Lin, Jia, Zhe, Cao, Weiguo, Alexov, Emil
Publicado 2019

Mutations in the KDM5C ARID Domain and Their Plausible Association with Syndromic Claes-Jensen-Type Disease

por Peng, Yunhui, Suryadi, Jimmy, Yang, Ye, Kucukkal, Tugba G., Cao, Weiguo, Alexov, Emil
Publicado 2015

Forces and Disease: Electrostatic force differences caused by mutations in kinesin motor domains can distinguish between disease-causing and non-disease-causing mutations

por Li, Lin, Jia, Zhe, Peng, Yunhui, Godar, Subash, Getov, Ivan, Teng, Shaolei, Alper, Joshua, Alexov, Emil
Publicado 2017

Aberrant DNA methylation and expression of EYA4 in gastric cardia intestinal metaplasia

por Li, Chenxi, Liu, Zhaohui, Xu, Guohua, Wu, Shibin, Peng, Yunhui, Wu, Ruinuan, Zhao, Shukun, Liao, Xiaoqi, Lin, Runhua
Publicado 2022

Rare missense variant p.Ala505Ser in the ZAK protein observed in a patient with split-hand/foot malformation from a non-consanguineous pedigree

por Funk, Christopher Ronald, Huey, Elizabeth S., May, Melanie M., Peng, Yunhui, Michonova, Ekaterina, Best, Robert G., Schwartz, Charles E., Blenda, Anna V.
Publicado 2020

DelPhi Suite: New Developments and Review of Functionalities

por Li, Chuan, Jia, Zhe, Chakravorty, Arghya, Pahari, Swagata, Peng, Yunhui, Basu, Sankar, Koirala, Mahesh, Panday, Shailesh Kumar, Petukh, Marharyta, Li, Lin, Alexov, Emil
Publicado 2019

Computational Analysis of Chemical Space of Natural Compounds Interacting with Sulfotransferases

por Lessigiarska, Iglika, Peng, Yunhui, Tsakovska, Ivanka, Alov, Petko, Lagarde, Nathalie, Jereva, Dessislava, Villoutreix, Bruno O., Nicot, Arnaud B., Pajeva, Ilza, Pencheva, Tania, Miteva, Maria A.
Publicado 2021

Increased p53 signaling impairs neural differentiation in HUWE1-promoted intellectual disabilities

por Aprigliano, Rossana, Aksu, Merdane Ezgi, Bradamante, Stefano, Mihaljevic, Boris, Wang, Wei, Rian, Kristin, Montaldo, Nicola P., Grooms, Kayla Mae, Fordyce Martin, Sarah L., Bordin, Diana L., Bosshard, Matthias, Peng, Yunhui, Alexov, Emil, Skinner, Cindy, Liabakk, Nina-Beate, Sullivan, Gareth J., Bjørås, Magnar, Schwartz, Charles E., van Loon, Barbara
Publicado 2021

Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy

por Lee, Yu-Ri, Khan, Kamal, Armfield-Uhas, Kim, Srikanth, Sujata, Thompson, Nicola A., Pardo, Mercedes, Yu, Lu, Norris, Joy W., Peng, Yunhui, Gripp, Karen W., Aleck, Kirk A., Li, Chumei, Spence, Ed, Choi, Tae-Ik, Kwon, Soo Jeong, Park, Hee-Moon, Yu, Daseuli, Heo, Won Do, Mooney, Marie R., Baig, Shahid M., Wentzensen, Ingrid M., Telegrafi, Aida, McWalter, Kirsty, Moreland, Trevor, Roadhouse, Chelsea, Ramsey, Keri, Lyons, Michael J., Skinner, Cindy, Alexov, Emil, Katsanis, Nicholas, Stevenson, Roger E., Choudhary, Jyoti S., Adams, David J., Kim, Cheol-Hee, Davis, Erica E., Schwartz, Charles E.
Publicado 2020