3253 Identification of Immune Cell Profiles and Molecular Pathways in Inflammatory Bowel Disease Driving Non-Response to Biologic Therapy

por Penrose, Harrison Michael, Nakhoul, Hani, Ungerleider, Nathan, Flemington, Erik, Savkovic, Suzana
Publicado 2019

STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells

por Penrose, Harrison M, Katsurada, Akemi, Miyata, Kayoko, Urushihara, Maki, Satou, Ryousuke
Publicado 2020

FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis

por Ghimire, Jenisha, Iftikhar, Rida, Penrose, Harrison M., Snarski, Patricia, Ruiz, Emmanuelle, Savkovic, Suzana D.
Publicado 2023

A comparison of linaclotide and lubiprostone dosing regimens on ion transport responses in human colonic mucosa

por Kang, Sang Bum, Marchelletta, Ronald R, Penrose, Harrison, Docherty, Michael J, McCole, Declan F
Publicado 2015

Trends in the Incidence of Early-Onset Colorectal Adenocarcinoma Among Black and White US Residents Aged 40 to 49 Years, 2000-2017

por Montminy, Eric M., Zhou, Meijiao, Maniscalco, Lauren, Penrose, Harrison, Yen, Timothy, Patel, Swati G., Wu, Xiao-Cheng, Karlitz, Jordan J.
Publicado 2021

FOXO3 Expression in Macrophages Is Lowered by a High-Fat Diet and Regulates Colonic Inflammation and Tumorigenesis

por Iftikhar, Rida, Penrose, Harrison M., King, Angelle N., Kim, Yunah, Ruiz, Emmanuelle, Kandil, Emad, Machado, Heather L., Savkovic, Suzana D.
Publicado 2022

In colonic ρ(0) (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer

por Penrose, Harrison M., Heller, Sandra, Cable, Chloe, Nakhoul, Hani, Ungerleider, Nate, Baddoo, Melody, Pursell, Zachary F., Flemington, Erik K., Crawford, Susan E., Savkovic, Suzana D.
Publicado 2017

Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

por Penrose, Harrison M., Iftikhar, Rida, Collins, Morgan E., Toraih, Eman, Ruiz, Emmanuelle, Ungerleider, Nathan, Nakhoul, Hani, Flemington, Erik F., Kandil, Emad, Shah, Shamita B., Savkovic, Suzana D.
Publicado 2021

The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn’s Disease but Not Ulcerative Colitis Patients

por Park, Young Su, Kang, Sang Bum, Marchelletta, Ronald R., Penrose, Harrison M., Ruiter-Visser, Roos, Jung, Barbara, Docherty, Michael J., Boland, Brigid S., Sandborn, William J., McCole, Declan F.
Publicado 2023

Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets

por Penrose, Harrison M., Cable, Chloe, Heller, Sandra, Ungerleider, Nathan, Nakhoul, Hani, Baddoo, Melody, Hartono, Alifiani B., Lee, Sean B., Burow, Matthew E., Flemington, Erik F., Crawford, Susan E., Savkovic, Suzana D.
Publicado 2018

Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

por Iftikhar, Rida, Penrose, Harrison M., King, Angelle N., Samudre, Joshua S., Collins, Morgan E., Hartono, Alifiani B., Lee, Sean B., Lau, Frank, Baddoo, Melody, Flemington, Erik F., Crawford, Susan E., Savkovic, Suzana D.
Publicado 2021

Correction: Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity

por Iftikhar, Rida, Penrose, Harrison M., King, Angelle N., Samudre, Joshua S., Collins, Morgan E., Hartono, Alifiani B., Lee, Sean B., Lau, Frank, Baddoo, Melody, Flemington, Erik F., Crawford, Susan E., Savkovic, Suzana D.
Publicado 2022